Genome engineering in actinomycetes using site-specific recombinases

Site-Specific Recombination Strategies for Engineering Actinomycete Genomes

(2012) Simone Herrmann et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Manipulating the regulatory genes for teicoplanin production in Actinoplanes teichomyceticus

(2012) Lilia Horbal et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Site-specific genome integration in alphaproteobacteria mediated by TG1 integrase

(2011) Kentaro Morita et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Analysis of the Site-Specific Integration System of the Streptomyces aureofaciens Phage μ1/6

(2011) Jarmila Farkašovská et al.   CURRENT MICROBIOLOGY

In vivo and in vitro characterization of site-specific recombination of actinophage R4 integrase

(2011) Takamasa Miura et al.   JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY

Streptomyces temperate bacteriophage integration systems for stable genetic engineering of actinomycetes (and other organisms)

(2011) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Over-expression of UDP-glucose pyrophosphorylase increases validamycin A but decreases validoxylamine A production in Streptomyces hygroscopicus var. jinggangensis 5008

(2011) Xiang Zhou et al.   METABOLIC ENGINEERING

Tandem assembly of the epothilone biosynthetic gene cluster by in vitro site-specific recombination

(2011) Lin Zhang et al.   Scientific Reports

Enhancement of the Diversity of Polyoxins by a Thymine-7-Hydroxylase Homolog outside the Polyoxin Biosynthesis Gene Cluster

(2010) C. Zhao et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Development of a Genetic System for Combinatorial Biosynthesis of Lipopeptides in Streptomyces fradiae and Heterologous Expression of the A54145 Biosynthesis Gene Cluster

(2010) D. C. Alexander et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Use of an inducible promoter for antibiotic production in a heterologous host

(2010) Volker Dangel et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Heterologous expression of the biosynthetic gene clusters of coumermycin A1, clorobiocin and caprazamycins in genetically modified Streptomyces coelicolor strains

(2010) Katrin Flinspach et al.   BIOPOLYMERS

Update on designing and building minimal cells

(2010) Michael C Jewett et al.   CURRENT OPINION IN BIOTECHNOLOGY

Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production

(2010) Guojian Liao et al.   Microbial Cell Factories

The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239

(2010) R. Novakova et al.   MICROBIOLOGY-SGM

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

(2010) M. Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Cleavage is Independent of Synapsis during Streptomyces Phage φBT1 Integrase-Mediated Site-Specific Recombination

(2010) Lin Zhang et al.   Journal of Molecular Cell Biology

Cleavage of Phosphorothioated DNA and Methylated DNA by the Type IV Restriction Endonuclease ScoMcrA

(2010) Guang Liu et al.   PLoS Genetics

Genome Mining inStreptomyces avermitilis: A Biochemical Baeyer−Villiger Reaction and Discovery of a New Branch of the Pentalenolactone Family Tree

(2009) Jiaoyang Jiang et al.   BIOCHEMISTRY

Domains involved in thein vivofunction and oligomerization of apical growth determinant DivIVA inStreptomyces coelicolor

(2009) Sheng-Bing Wang et al.   FEMS MICROBIOLOGY LETTERS

The site-specific recombination system of actinophage TG1

(2009) Kentaro Morita et al.   FEMS MICROBIOLOGY LETTERS

A gene cloning system for the siomycin producer Streptomyces sioyaensis NRRL-B5408

(2009) M. Myronovskyy et al.   FOLIA MICROBIOLOGICA

Use of the native flp gene to generate in-frame unmarked mutations in Streptomyces spp.

(2009) Nathan Zelyas et al.   GENE

Rapid Cloning and Heterologous Expression of the Meridamycin Biosynthetic Gene Cluster Using a VersatileEscherichia coli−StreptomycesArtificial Chromosome Vector, pSBAC⊥

(2009) Hongbo Liu et al.   JOURNAL OF NATURAL PRODUCTS

Challenging a Paradigm: the Role of DNA Homology in Tyrosine Recombinase Reactions

(2009) L. Rajeev et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

In vitro characterization of the site-specific recombination system based on actinophage TG1 integrase

(2009) Kentaro Morita et al.   MOLECULAR GENETICS AND GENOMICS

Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids

(2009) Bohdan Ostash et al.   PLASMID

Functional expression of the Cre recombinase in actinomycetes

(2008) Marta Fedoryshyn et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Application of conjugation using ϕC31 att/int system for Actinoplanes teichomyceticus, a producer of teicoplanin

(2008) Heon-Su Ha et al.   BIOTECHNOLOGY LETTERS

Marker removal from actinomycetes genome using Flp recombinase

(2008) Marta Fedoryshyn et al.   GENE

Highly Efficient In Vitro Site-Specific Recombination System Based on Streptomyces Phage  BT1 Integrase

(2008) L. Zhang et al.   JOURNAL OF BACTERIOLOGY

In VivoManipulation of the Bleomycin Biosynthetic Gene Cluster inStreptomyces verticillusATCC15003 Revealing New Insights into Its Biosynthetic Pathway

(2008) Ute Galm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Site-Specific Transgene Integration in the Human Genome Catalyzed by φBT1 Phage Integrase

(2007) Li Chen et al.   HUMAN GENE THERAPY