ω3 fatty acid desaturases from microorganisms: structure, function, evolution, and biotechnological use

Reconstitution of EPA and DHA biosynthesis in Arabidopsis: Iterative metabolic engineering for the synthesis of n−3 LC-PUFAs in transgenic plants

(2013) Noemi Ruiz-Lopez et al.   METABOLIC ENGINEERING

Expression and Purification of Integral Membrane Fatty Acid Desaturases

(2013) Haiqin Chen et al.   PLoS One

Identification and evaluation of ω-3 fatty acid desaturase genes for hyperfortifying α-linolenic acid in transgenic rice seed

(2012) Hua Liang Liu et al.   JOURNAL OF EXPERIMENTAL BOTANY

Metabolic Engineering Plant Seeds with Fish Oil-Like Levels of DHA

(2012) James R. Petrie et al.   PLoS One

Mechanistic and Structural Insights into the Regioselectivity of an Acyl-CoA Fatty Acid Desaturase via Directed Molecular Evolution

(2011) Thomas Vanhercke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Front-end Desaturase: Structure, Function, Evolution and Biotechnological Use

(2011) Dauenpen Meesapyodsuk et al.   LIPIDS

Comparative genomic analysis of the thermophilic biomass-degrading fungi Myceliophthora thermophila and Thielavia terrestris

(2011) Randy M Berka et al.   NATURE BIOTECHNOLOGY

Genome Characterization of the Oleaginous Fungus Mortierella alpina

(2011) Lei Wang et al.   PLoS One

A Novel Omega-3 Fatty Acid Desaturase Involved in Acclimation Processes of Polar Condition from Antarctic Ice Algae Chlamydomonas sp. ICE-L

(2010) Pengying Zhang et al.   MARINE BIOTECHNOLOGY

Establishment of Agrobacterium tumefaciens-Mediated Transformation of an Oleaginous Fungus, Mortierella alpina 1S-4, and Its Application for Eicosapentaenoic Acid Producer Breeding

(2009) A. Ando et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Structural Control of Chemoselectivity, Stereoselectivity, and Substrate Specificity in Membrane-Bound Fatty Acid Acetylenases and Desaturases

(2009) Steve J. Gagné et al.   BIOCHEMISTRY

Desaturases: Emerging Models for Understanding Functional Diversification of Diiron-containing Enzymes

(2009) John Shanklin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of mutation sites on ω3 desaturase genes from Mortierella alpina 1S-4 mutants

(2009) Eiji Sakuradani et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Substrate Specificity and Regioselectivity of Δ12 and ω3 Fatty Acid Desaturases fromSaccharomyces kluyveri

(2008) Takahiro OURA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Reduced Colitis-Associated Colon Cancer in Fat-1 (n-3 Fatty Acid Desaturase) Transgenic Mice

(2008) Q. Jia et al.   CANCER RESEARCH

Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3β phosphorylation

(2008) Yi Lu et al.   MOLECULAR CANCER THERAPEUTICS

Identification and characterization of a novel yeast ω3-fatty acid desaturase acting on long-chain n-6 fatty acid substrates fromPichia pastoris

(2007) Xinxin Zhang et al.   YEAST

X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv

(2005) David H. Dyer et al.   PROTEIN SCIENCE