The benefits of being transient: isotope-based metabolic flux analysis at the short time scale

Metabolomic approaches toward understanding nitrogen metabolism in plants

(2011) M. Kusano et al.   JOURNAL OF EXPERIMENTAL BOTANY

Evaluation of Peak Picking Quality in LC−MS Metabolomics Data

(2010) Leonid Brodsky et al.   ANALYTICAL CHEMISTRY

Nontargeted Elucidation of Metabolic Pathways Using Stable-Isotope Tracers and Mass Spectrometry

(2010) Karsten Hiller et al.   ANALYTICAL CHEMISTRY

Metabolic flux distributions: genetic information, computational predictions, and experimental validation

(2010) Lars M. Blank et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Tracer-based metabolomics: Concepts and practices

(2010) W-N. Paul Lee et al.   CLINICAL BIOCHEMISTRY

From fluxes and isotope labeling patterns towards in silico cells

(2010) Michael Dauner   CURRENT OPINION IN BIOTECHNOLOGY

Metabolic flux analysis in eukaryotes

(2010) Jens Niklas et al.   CURRENT OPINION IN BIOTECHNOLOGY

Fast sampling for quantitative microbial metabolomics

(2010) Walter M van Gulik   CURRENT OPINION IN BIOTECHNOLOGY

13C metabolic flux analysis in complex systems

(2010) Nicola Zamboni   CURRENT OPINION IN BIOTECHNOLOGY

CE-MS for metabolomics: Developments and applications in the period 2008-2010

(2010) Rawi Ramautar et al.   ELECTROPHORESIS

Isotopologue Profiling ofLegionella pneumophila

(2010) Eva Eylert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

13C metabolic flux analysis for larger scale cultivation using gas chromatography-combustion-isotope ratio mass spectrometry

(2010) Yongbo Yuan et al.   METABOLIC ENGINEERING

BioMet Toolbox: genome-wide analysis of metabolism

(2010) M. Cvijovic et al.   NUCLEIC ACIDS RESEARCH

Quantitative Evaluation of Intracellular Metabolite Extraction Techniques for Yeast Metabolomics

(2009) André B. Canelas et al.   ANALYTICAL CHEMISTRY

Rapid sampling devices for metabolic engineering applications

(2009) Friederike Schädel et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Metabolic turnover analysis by a combination of in vivo13C-labelling from 13CO2 and metabolic profiling with CE-MS/MS reveals rate-limiting steps of the C3 photosynthetic pathway in Nicotiana tabacum leaves

(2009) Tomohisa Hasunuma et al.   JOURNAL OF EXPERIMENTAL BOTANY

Quantification of statin effects on hepatic cholesterol synthesis by transient 13C-flux analysis

(2009) Klaus Maier et al.   METABOLIC ENGINEERING

Improved computational performance of MFA using elementary metabolite units and flux coupling

(2009) Patrick F. Suthers et al.   METABOLIC ENGINEERING

OpenFLUX: efficient modelling software for 13C-based metabolic flux analysis

(2009) Lake-Ee Quek et al.   Microbial Cell Factories

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

(2009) Bryson D Bennett et al.   Nature Chemical Biology

13C-based metabolic flux analysis

(2009) Nicola Zamboni et al.   Nature Protocols

Metabolic flux analysis in plants: coping with complexity

(2009) DOUG K. ALLEN et al.   PLANT CELL AND ENVIRONMENT

Subcellular Flux Analysis of Central Metabolism in a Heterotrophic Arabidopsis Cell Suspension Using Steady-State Stable Isotope Labeling

(2009) S. K. Masakapalli et al.   PLANT PHYSIOLOGY

Development and application of a differential method for reliable metabolome analysis in Escherichia coli

(2008) Hilal Taymaz-Nikerel et al.   ANALYTICAL BIOCHEMISTRY

13C labeling experiments at metabolic nonstationary conditions: An exploratory study

(2008) Sebastian Wahl et al.   BMC BIOINFORMATICS

Hybrid optimization for 13C metabolic flux analysis using systems parametrized by compactification

(2008) Tae Hoon Yang et al.   BMC Systems Biology

Metabolic flux analysis as a tool in metabolic engineering of plants

(2008) Jörg Schwender   CURRENT OPINION IN BIOTECHNOLOGY

Separation and mass spectrometry in microbial metabolomics

(2008) David E Garcia et al.   CURRENT OPINION IN MICROBIOLOGY

Dynamic13C-tracer study of storage carbohydrate pools in aerobic glucose-limitedSaccharomyces cerevisiaeconfirms a rapid steady-state turnover and fast mobilization during a modest stepup in the glucose uptake rate

(2008) Fredrick O. Aboka et al.   FEMS YEAST RESEARCH

Isotopic non-stationary 13C gluconate tracer method for accurate determination of the pentose phosphate pathway split-ratio in Penicillium chrysogenum

(2008) Zheng Zhao et al.   METABOLIC ENGINEERING

Leakage of adenylates during cold methanol/glycerol quenching of Escherichia coli

(2008) Hannes Link et al.   Metabolomics

Leakage-free rapid quenching technique for yeast metabolomics

(2008) André B. Canelas et al.   Metabolomics

From biomarkers to integrated network responses

(2008) Uwe Sauer et al.   NATURE BIOTECHNOLOGY

Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

(2008) Joshua Munger et al.   NATURE BIOTECHNOLOGY

Kinetic flux profiling for quantitation of cellular metabolic fluxes

(2008) Jie Yuan et al.   Nature Protocols

An elementary metabolite unit (EMU) based method of isotopically nonstationary flux analysis

(2007) Jamey D. Young et al.   BIOTECHNOLOGY AND BIOENGINEERING

Identification of metabolic fluxes in hepatic cells from transient13C-labeling experiments: Part I. Experimental observations

(2007) Ute Hofmann et al.   BIOTECHNOLOGY AND BIOENGINEERING

Metabolic flux analysis inEscherichia coli by integrating isotopic dynamic and isotopic stationary13C labeling data

(2007) Jochen Schaub et al.   BIOTECHNOLOGY AND BIOENGINEERING

Identification of metabolic fluxes in hepatic cells from transient13C-labeling experiments: Part II. Flux estimation

(2007) Klaus Maier et al.   BIOTECHNOLOGY AND BIOENGINEERING

Depiction of metabolome changes in histidine-starvedEscherichia coliby CE-TOFMS

(2007) Yoshiaki Ohashi et al.   Molecular BioSystems