Identification of Druggable Targets for Acinetobacter baumannii Via Subtractive Genomics and Plausible Inhibitors for MurA and MurB

Subtractive Genomics Approach to Identify Putative Drug Targets and Identification of Drug-like Molecules for Beta Subunit of DNA Polymerase III in Streptococcus Species

(2012) John J. Georrge et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Reorganizing the protein space at the Universal Protein Resource (UniProt)

(2011)   NUCLEIC ACIDS RESEARCH

Bacterial cell wall assembly: still an attractive antibacterial target

(2011) Timothy D.H. Bugg et al.   TRENDS IN BIOTECHNOLOGY

Are we closing in on an "elusive enemy"? The current status of our battle withAcinetobacter baumannii

(2011) Federico Perez et al.   Virulence

The Fungal Product Terreic Acid Is a Covalent Inhibitor of the Bacterial Cell Wall Biosynthetic Enzyme UDP-N-Acetylglucosamine 1-Carboxyvinyltransferase (MurA),

(2010) Huijong Han et al.   BIOCHEMISTRY

PSORTb 3.0: improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes

(2010) Nancy Y. Yu et al.   BIOINFORMATICS

Structure–activity relationships of tulipalines, tuliposides, and related compounds as inhibitors of MurA

(2010) Thomas Mendgen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Virtual Screening of potential drug-like inhibitors against Lysine/DAP pathway of Mycobacterium tuberculosis

(2010) Aarti Garg et al.   BMC BIOINFORMATICS

KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials

(2010) Aarti Garg et al.   BMC BIOINFORMATICS

Peptidoglycan biosynthesis machinery: A rich source of drug targets

(2010) Ankur Gautam et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

In silico subtractive genomics for target identification in human bacterial pathogens

(2010) Debmalya Barh et al.   DRUG DEVELOPMENT RESEARCH

Identification of hotspot regions of MurB oxidoreductase enzyme using homology modeling, molecular dynamics and molecular docking techniques

(2010) Vivek Kumar et al.   JOURNAL OF MOLECULAR MODELING

In silico analysis of antibody triggering biofilm associated protein in Acinetobacter baumannii

(2010) Mohammad Reza Rahbar et al.   JOURNAL OF THEORETICAL BIOLOGY

Evidence of Kinetic Control of Ligand Binding and Staged Product Release in MurA (Enolpyruvyl UDP-GlcNAc Synthase)-Catalyzed Reactions,

(2009) Sean G. Jackson et al.   BIOCHEMISTRY

An oldie but a goodie – cell wall biosynthesis as antibiotic target pathway

(2009) Tanja Schneider et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

2-Aminotetralones: Novel inhibitors of MurA and MurZ

(2008) Colin J. Dunsmore et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Current control and treatment of multidrug-resistant Acinetobacter baumannii infections

(2008) Drosos E Karageorgopoulos et al.   LANCET INFECTIOUS DISEASES

DEG 5.0, a database of essential genes in both prokaryotes and eukaryotes

(2008) R. Zhang et al.   NUCLEIC ACIDS RESEARCH