Eukaryotic elongation factor-2 kinase (eEF2K): a potential therapeutic target in cancer

Germline Quality Control: eEF2K Stands Guard to Eliminate Defective Oocytes

(2014) Hsueh-Ping Chu et al.   DEVELOPMENTAL CELL

Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons

(2014) Christopher Heise et al.   Frontiers in Cellular Neuroscience

Targeting elongation factor-2 kinase (eEF-2K) induces apoptosis in human pancreatic cancer cells

(2013) Ahmed A. Ashour et al.   APOPTOSIS

The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation

(2013) Gabriel Leprivier et al.   CELL

Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer

(2013) B Liu et al.   Cell Death & Disease

Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells

(2012) Yan Cheng et al.   Autophagy

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

(2012) Sébastien Pyr Dit Ruys et al.   BIOCHEMICAL JOURNAL

eEF-2 kinase, another meddler in the “Yin and Yang” of Akt–mediated cell fate?

(2011) Yan Cheng et al.   Autophagy

Inhibition of eEF-2 kinase sensitizes human glioma cells to TRAIL and down-regulates Bcl-xL expression

(2011) Yi Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Insights into the regulation of eukaryotic elongation factor 2 kinase and the interplay between its domains

(2011) Craig R. Pigott et al.   BIOCHEMICAL JOURNAL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) Induces Phosphorylation of Eukaryotic Elongation Factor-2 (eEF2)

(2011) Zehan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting apoptotic and autophagic pathways for cancer therapeutics

(2010) Jun-jie Liu et al.   CANCER LETTERS

Cytoprotective Effect of the Elongation Factor-2 Kinase-Mediated Autophagy in Breast Cancer Cells Subjected to Growth Factor Inhibition

(2010) Yan Cheng et al.   PLoS One

Silencing of Elongation Factor-2 Kinase Potentiates the Effect of 2-Deoxy-D-Glucose against Human Glioma Cells through Blunting of Autophagy

(2009) H. Wu et al.   CANCER RESEARCH

The role of protein synthesis in cell cycling and cancer

(2009) Shai White-Gilbertson et al.   Molecular Oncology