Amplification activation loop between caspase-8 and -9 dominates artemisinin-induced apoptosis of ASTC-a-1 cells

The JNK inhibitor SP600125 enhances dihydroartemisinin-induced apoptosis by accelerating Bax translocation into mitochondria in human lung adenocarcinoma cells

(2010) Ying-Ying Lu et al.   FEBS LETTERS

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials

(2010) Amy E. Mercer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production

(2010) Anne Hamacher-Brady et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-cell analysis of dihydroartemisinin–induced apoptosis through reactive oxygen species–mediated caspase-8 activation and mitochondrial pathway in ASTC-a-1 cells using fluorescence imaging techniques

(2010) Ying-Ying Lu et al.   JOURNAL OF BIOMEDICAL OPTICS

Dihydroartemisinin Induces Apoptosis by a Bak-Dependent Intrinsic Pathway

(2010) R. Handrick et al.   MOLECULAR CANCER THERAPEUTICS

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines

(2009) Martin Michaelis et al.   BIOCHEMICAL PHARMACOLOGY

Autocrine amplification loop in statin-induced apoptosis of human melanoma cells

(2009) C Minichsdorfer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

(2009) Hyungjin Kim et al.   MOLECULAR CELL

Etoposide Induces Protein Kinase C - and Caspase-3-Dependent Apoptosis in Neuroblastoma Cancer Cells

(2009) T. W. Day et al.   MOLECULAR PHARMACOLOGY

Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells

(2008) S. N. Sundar et al.   CARCINOGENESIS

Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax

(2008) Jonathan F. Lovell et al.   CELL

Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation

(2008) Sanjeev Shukla et al.   FREE RADICAL BIOLOGY AND MEDICINE

Leptospira interrogans Induces Apoptosis in Macrophages via Caspase-8- and Caspase-3-Dependent Pathways

(2008) D. Jin et al.   INFECTION AND IMMUNITY

ADP-Ribosylation of Actin by the Clostridium botulinum C2 Toxin in Mammalian Cells Results in Delayed Caspase-Dependent Apoptotic Cell Death

(2008) K. Heine et al.   INFECTION AND IMMUNITY

Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expression

(2008) Jamin A. Willoughby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Murine Caspase-9 by the Protein Kinase Casein Kinase 2 Regulates Its Cleavage by Caspase-8

(2008) Maureen A. McDonnell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy

(2008) Tao Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE