Higenamine reduces HMGB1 during hypoxia-induced brain injury by induction of heme oxygenase-1 through PI3K/Akt/Nrf-2 signal pathways

Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury via PI3K/Akt pathway

(2010) Jun-Kuan Wang et al.   BRAIN RESEARCH

Metformin inhibits HMGB1 release in LPS-treated RAW 264.7 cells and increases survival rate of endotoxaemic mice

(2010) Konstantin Tsoyi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium

(2010) Shahir S. Hamdulay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuroglobin Protects Neurons against Oxidative Stress in Global Ischemia

(2010) Richard Changxun Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Minocycline attenuates both OGD-induced HMGB1 release and HMGB1-induced cell death in ischemic neuronal injury in PC12 cells

(2009) Kiyoshi Kikuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

EP2 receptor activation by prostaglandin E2 leads to induction of HO-1 via PKA and PI3K pathways in C6 cells

(2009) Min Kyu Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

(S)-1-( -Naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712) Reduces Rat Myocardial Apoptosis against Ischemia and Reperfusion Injury by Activation of Phosphatidylinositol 3-Kinase/Akt Signaling and Anti-inflammatory Action in Vivo

(2009) Y. C. Jin et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Heme-Oxygenase-1 Induction and Carbon Monoxide-Releasing Molecule Inhibit Lipopolysaccharide (LPS)-Induced High-Mobility Group Box 1 Release in Vitro and Improve Survival of Mice in LPS- and Cecal Ligation and Puncture-Induced Sepsis Model in Vivo

(2009) K. Tsoyi et al.   MOLECULAR PHARMACOLOGY

High-Mobility Group Box 1 Contributes to Lethality of Endotoxemia in Heme Oxygenase-1–Deficient Mice

(2008) Rina Takamiya et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The obligatory role of COX-2 expression for induction of HO-1 in ischemic preconditioned rat brain

(2008) Min Kyu Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heme Oxygenase: A Target Gene for Anti-Diabetic and Obesity

(2008) N. Abraham et al.   CURRENT PHARMACEUTICAL DESIGN

Induction and subcellular localization of high-mobility group box–1 (HMGB1) in the postischemic rat brain

(2007) Jung-Bin Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH