Regulation of apoptosis in human melanoma and neuroblastoma cells by statins, sodium arsenite and TRAIL: a role of combined treatment versus monotherapy

Targeting BRAF in Advanced Melanoma: A First Step toward Manageable Disease

(2011) A. Vultur et al.   CLINICAL CANCER RESEARCH

Long-Term Use of Nonsteroidal Anti-inflammatory Drugs Decreases the Risk of Cutaneous Melanoma: Results of a United States Case–Control Study

(2011) Clara Curiel-Lewandrowski et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Simvastatin impairs murine melanoma growth

(2011) Giovani M Favero et al.   Lipids in Health and Disease

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential

(2010) Ananta Paine et al.   BIOCHEMICAL PHARMACOLOGY

Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710

(2010) B. L. Powell et al.   BLOOD

Mitochondrial Dysfunction Induced by Statin Contributes to Endothelial Dysfunction in Patients with Coronary Artery Disease

(2010) Yuk-Ling Dai et al.   Cardiovascular Toxicology

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Disruption of IGF-1R signaling increases TRAIL-induced apoptosis: A new potential therapy for the treatment of melanoma

(2010) Thomas B. Karasic et al.   EXPERIMENTAL CELL RESEARCH

Suppression of the proinflammatory response of metastatic melanoma cells increases TRAIL-induced apoptosis

(2010) Vladimir N. Ivanov et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

How melanomas bypass new therapy

(2010) David Solit et al.   NATURE

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

(2010) Poulikos I. Poulikakos et al.   NATURE

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

(2010) Gideon Bollag et al.   NATURE

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

(2010) Ramin Nazarian et al.   NATURE

Autocrine amplification loop in statin-induced apoptosis of human melanoma cells

(2009) C Minichsdorfer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Curcumin Potentiates the Antitumor Effects of Bacillus Calmette-Guerin against Bladder Cancer through the Downregulation of NF- B and Upregulation of TRAIL Receptors

(2009) A. M. Kamat et al.   CANCER RESEARCH

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

Targeting the Mevalonate Pathway for Improved Anticancer Therapy

(2009) G. Fritz   CURRENT CANCER DRUG TARGETS

Can statin therapy reduce the risk of melanoma? A meta-analysis of randomized controlled trials

(2009) Stefanos Bonovas et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells

(2009) Elena V. Sviderskaya et al.   FASEB JOURNAL

Induction of the Cytoprotective Enzyme Heme Oxygenase-1 by Statins Is Enhanced in Vascular Endothelium Exposed to Laminar Shear Stress and Impaired by Disturbed Flow

(2009) Faisal Ali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells

(2009) Akira Saito et al.   MELANOMA RESEARCH

SIMVASTATIN ATTENUATES MICROGLIAL CELLS AND ASTROCYTE ACTIVATION AND DECREASES INTERLEUKIN-1B LEVEL AFTER TRAUMATIC BRAIN INJURY

(2009) Bo Li et al.   NEUROSURGERY

NF- B as a Critical Link Between Inflammation and Cancer

(2009) M. Karin   Cold Spring Harbor Perspectives in Biology

Molecular Pathogenesis of Cutaneous Melanocytic Neoplasms

(2008) Nageatte Ibrahim et al.   Annual Review of Pathology-Mechanisms of Disease

The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

(2008) Sharon A Glynn et al.   BMC CANCER

Ligand-Based Targeting of Apoptosis in Cancer: The Potential of Recombinant Human Apoptosis Ligand 2/Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (rhApo2L/TRAIL)

(2008) Avi Ashkenazi et al.   JOURNAL OF CLINICAL ONCOLOGY

Apoptosome-deficient Cells Lose Cytochrome c through Proteasomal Degradation but Survive by Autophagy-dependent Glycolysis

(2008) Elisabetta Ferraro et al.   MOLECULAR BIOLOGY OF THE CELL

Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression

(2007) Vladimir N. Ivanov et al.   EXPERIMENTAL CELL RESEARCH