Experimental autoimmune encephalomyelitis - achievements and prospective advances

Host T Cells Are the Main Producers of IL-17 within the Central Nervous System during Initiation of Experimental Autoimmune Encephalomyelitis Induced by Adoptive Transfer of Th1 Cell Lines

(2014) J. R. Lees et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Th1 Cells Facilitate the Entry of Th17 Cells to the Central Nervous System during Experimental Autoimmune Encephalomyelitis

(2014) R. A. O'Connor et al.   JOURNAL OF IMMUNOLOGY

The role of antibodies in multiple sclerosis

(2010) Martin S. Weber et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Detection of Epstein–Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look

(2010) Francesca Aloisi et al.   BRAIN

IL-17 family member cytokines: Regulation and function in innate immunity

(2010) Joseph M. Reynolds et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Genetic proof for the transient nature of the Th17 phenotype

(2010) Florian C. Kurschus et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

EAE mediated by a non-IFN-γ/non-IL-17 pathway

(2010) Mark A. Kroenke et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Epigenetic Instability of Cytokine and Transcription Factor Gene Loci Underlies Plasticity of the T Helper 17 Cell Lineage

(2010) Ryuta Mukasa et al.   IMMUNITY

Identification of a novel subset of human circulating memory CD4+ T cells that produce both IL-17A and IL-4

(2010) Lorenzo Cosmi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Vitamin D and multiple sclerosis

(2010) Alberto Ascherio et al.   LANCET NEUROLOGY

Effector T cell plasticity: flexibility in the face of changing circumstances

(2010) Kenneth M Murphy et al.   NATURE IMMUNOLOGY

Absence of Epstein-Barr virus in the brain and CSF of patients with multiple sclerosis

(2010) S. A. Sargsyan et al.   NEUROLOGY

Functional and Pathogenic Differences of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

(2010) Helena S. Domingues et al.   PLoS One

The cuprizone animal model: new insights into an old story

(2009) Markus Kipp et al.   ACTA NEUROPATHOLOGICA

Epstein Barr virus is not a characteristic feature in the central nervous system in established multiple sclerosis

(2009) Laura A. N. Peferoen et al.   BRAIN

Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain

(2009) Simon N. Willis et al.   BRAIN

Upregulation of Immunoglobulin-related Genes in Cortical Sections from Multiple Sclerosis Patients

(2009) Øivind Torkildsen et al.   BRAIN PATHOLOGY

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells

(2009) Natalia Martin-Orozco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

Transforming growth factor β is dispensable for the molecular orchestration of Th17 cell differentiation

(2009) Jyoti Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells

(2009) Bernadette Pöllinger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes

(2009) A. Jager et al.   JOURNAL OF IMMUNOLOGY

TGF-  Promotes Th17 Cell Development through Inhibition of SOCS3

(2009) H. Qin et al.   JOURNAL OF IMMUNOLOGY

Experimental Autoimmune Encephalomyelitis in the Common Marmoset, a Bridge Between Rodent EAE and Multiple Sclerosis for Immunotherapy Development

(2009) Yolanda S. Kap et al.   Journal of Neuroimmune Pharmacology

Neuropathogenesis of Theiler’s Murine Encephalomyelitis Virus Infection, An Animal Model for Multiple Sclerosis

(2009) Ikuo Tsunoda et al.   Journal of Neuroimmune Pharmacology

Encephalitogenic T cells that stably express both T-bet and RORγt consistently produce IFNγ but have a spectrum of IL-17 profiles

(2009) Sara Abromson-Leeman et al.   JOURNAL OF NEUROIMMUNOLOGY

Clinical, Pathological, and Immunologic Aspects of the Multiple Sclerosis Model in Common Marmosets (Callithrix jacchus)

(2009) Bert A. 't Hart et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Meningeal Inflammation is not Associated With Cortical Demyelination in Chronic Multiple Sclerosis

(2009) Evert-Jan Kooi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Fundamental differences in the dynamics of CNS lesion development and composition in MP4- and MOG peptide 35–55-induced experimental autoimmune encephalomyelitis

(2008) Stefanie Kuerten et al.   CLINICAL IMMUNOLOGY

Impact of myelin-specific antigen presenting B cells on T cell activation in multiple sclerosis

(2008) Christopher T. Harp et al.   CLINICAL IMMUNOLOGY

The role of B cells in multiple sclerosis: rationale for B-cell-targeted therapies

(2008) Michael K Racke   CURRENT OPINION IN NEUROLOGY

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

Autoantibodies and neurodegeneration in multiple sclerosis

(2008) Tamara Vyshkina et al.   LABORATORY INVESTIGATION

B cells and multiple sclerosis

(2008) Diego Franciotta et al.   LANCET NEUROLOGY

Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

(2008) Ingunn M Stromnes et al.   NATURE MEDICINE

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

(2007) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY