Respiratory Syncytial Virus Infection: Mechanisms of Redox Control and Novel Therapeutic Opportunities

In VitroAntiviral Activity of Resveratrol Against Respiratory Viruses

(2014) L. Drago et al.   JOURNAL OF CHEMOTHERAPY

Dual Role of NOX2 in Respiratory Syncytial Virus- and Sendai Virus-Induced Activation of NF- B in Airway Epithelial Cells

(2014) K. Fink et al.   JOURNAL OF IMMUNOLOGY

Functional Haplotypes in the Promoter Region of Transcription FactorNrf2in Chronic Obstructive Pulmonary Disease

(2013) Chung-Ching Hua et al.   DISEASE MARKERS

Viral-mediated Inhibition of Antioxidant Enzymes Contributes to the Pathogenesis of Severe Respiratory Syncytial Virus Bronchiolitis

(2011) Yashoda M. Hosakote et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

N-acetyl-l-cysteine (NAC) inhibit mucin synthesis and pro-inflammatory mediators in alveolar type II epithelial cells infected with influenza virus A and B and with respiratory syncytial virus (RSV)

(2011) Manuel Mata et al.   BIOCHEMICAL PHARMACOLOGY

Nrf2 expression modifies influenza A entry and replication in nasal epithelial cells

(2011) Matthew J. Kesic et al.   FREE RADICAL BIOLOGY AND MEDICINE

Respiratory Syncytial Virus Load, Viral Dynamics, and Disease Severity in Previously Healthy Naturally Infected Children

(2011) Chadi M. El Saleeby et al.   JOURNAL OF INFECTIOUS DISEASES

Confirmation of an association between single nucleotide polymorphisms in the VDR gene with respiratory syncytial virus related disease in South African Children

(2011) T.L. Kresfelder et al.   JOURNAL OF MEDICAL VIROLOGY

New Synthetic Triterpenoids: Potent Agents for Prevention and Treatment of Tissue Injury Caused by Inflammatory and Oxidative Stress

(2011) Michael B. Sporn et al.   JOURNAL OF NATURAL PRODUCTS

Differential Pathogenesis of Respiratory Syncytial Virus Clinical Isolates in BALB/c Mice

(2011) K. L. Stokes et al.   JOURNAL OF VIROLOGY

Resveratrol-Mediated Gamma Interferon Reduction Prevents Airway Inflammation and Airway Hyperresponsiveness in Respiratory Syncytial Virus-Infected Immunocompromised Mice

(2011) N. Zang et al.   JOURNAL OF VIROLOGY

Rhinovirus-Induced Barrier Dysfunction in Polarized Airway Epithelial Cells Is Mediated by NADPH Oxidase 1

(2011) A. T. Comstock et al.   JOURNAL OF VIROLOGY

Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment

(2011) Purusotam Basnet et al.   MOLECULES

Antioxidant Therapy as a Potential Approach to Severe Influenza-Associated Complications

(2011) Noboru Uchide et al.   MOLECULES

Cord Blood Vitamin D Deficiency Is Associated With Respiratory Syncytial Virus Bronchiolitis

(2011) M. E. Belderbos et al.   PEDIATRICS

Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection

(2011) A M Fonceca et al.   THORAX

TAK1 regulates NF-ΚB and AP-1 activation in airway epithelial cells following RSV infection

(2011) Nilay Dey et al.   VIROLOGY

Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

(2011) Ross Vlahos et al.   PLoS Pathogens

Antioxidant and Anti-Inflammatory Effects of Resveratrol in Airway Disease

(2010) Lisa G. Wood et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Control of Protein–DNA Interactions: From Molecular Mechanisms to Significance in Signal Transduction, Gene Expression, and DNA Replication

(2010) Joseph Shlomai   ANTIOXIDANTS & REDOX SIGNALING

When NRF2 Talks, Who's Listening?

(2010) Nobunao Wakabayashi et al.   ANTIOXIDANTS & REDOX SIGNALING

Superoxide Dismutase Mimics: Chemistry, Pharmacology, and Therapeutic Potential

(2010) Ines Batinić-Haberle et al.   ANTIOXIDANTS & REDOX SIGNALING

Exhaled Nitric Oxide in Acute Respiratory Syncytial Virus Bronchiolitis

(2010) Tal Gadish et al.   ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE

A Small-Molecule Inducer of the Antioxidant Response Element

(2010) Wooyoung Hur et al.   CHEMISTRY & BIOLOGY

Small molecule modulators of antioxidant response pathway

(2010) Wooyoung Hur et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Pharmacotherapy of respiratory syncytial virus infection

(2010) Robert C Welliver   CURRENT OPINION IN PHARMACOLOGY

Inhibitory effect of melatonin on lung oxidative stress induced by respiratory syncytial virus infection in mice

(2010) Sheng-Hai Huang et al.   JOURNAL OF PINEAL RESEARCH

Role of Peroxiredoxin 1 and Peroxiredoxin 4 in Protection of Respiratory Syncytial Virus-Induced Cysteinyl Oxidation of Nuclear Cytoskeletal Proteins

(2010) M. Jamaluddin et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus-Mediated NF- B p65 Phosphorylation at Serine 536 Is Dependent on RIG-I, TRAF6, and IKK 

(2010) F. Yoboua et al.   JOURNAL OF VIROLOGY

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo - Studies in electrophile response element transgenic mice

(2010) Trude Rakel Balstad et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Maturation of the antioxidant system and the effects on preterm birth

(2010) Jonathan M. Davis et al.   Seminars in Fetal & Neonatal Medicine

IKKε modulates RSV-induced NF-κB-dependent gene transcription

(2010) Xiaoyong Bao et al.   VIROLOGY

Requirement of NOX2 and Reactive Oxygen Species for Efficient RIG-I-Mediated Antiviral Response through Regulation of MAVS Expression

(2010) Anton Soucy-Faulkner et al.   PLoS Pathogens

The triterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease

(2009) David P. Nichols et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Triterpenoid CDDO-Imidazolide Confers Potent Protection against Hyperoxic Acute Lung Injury in Mice

(2009) Narsa M. Reddy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Respiratory Syncytial Virus Induces Oxidative Stress by Modulating Antioxidant Enzymes

(2009) Yashoda M. Hosakote et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Oxidative Stress Enhances Toll-Like Receptor 3 Response to Double-Stranded RNA in Airway Epithelial Cells

(2009) Akira Koarai et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Nrf2:INrf2 (Keap1) signaling in oxidative stress

(2009) James W. Kaspar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Respiratory Syncytial Virus Inhibits Lung Epithelial Na+Channels by Up-regulating Inducible Nitric-oxide Synthase

(2009) Weifeng Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cerebrospinal fluid NOx (nitrite/nitrate) in RSV-infected children with CNS symptoms

(2009) Shinichiro Morichi et al.   JOURNAL OF INFECTION

Respiratory Syncytial Virus Infection Induces a Reactive Oxygen Species-MSK1-Phospho-Ser-276 RelA Pathway Required for Cytokine Expression

(2009) M. Jamaluddin et al.   JOURNAL OF VIROLOGY

The Burden of Respiratory Syncytial Virus Infection in Young Children

(2009) Caroline Breese Hall et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human milk enhances antioxidant defenses against hydroxyl radical aggression in preterm infants

(2008) Ana Ledo et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Antiviral Activity of Nrf2 in a Murine Model of Respiratory Syncytial Virus Disease

(2008) Hye-Youn Cho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhibition of Na+Transport in Lung Epithelial Cells by Respiratory Syncytial Virus Infection

(2008) Lan Chen et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[ a ]pyrene-treated mice: mechanism of its anti-initiating action

(2008) Rachana Garg et al.   CARCINOGENESIS

O2 Sensing: Only Skin Deep?

(2008) Gregg L. Semenza   CELL

Human Genetic Factors and Respiratory Syncytial Virus Disease Severity

(2008) I. Miyairi et al.   CLINICAL MICROBIOLOGY REVIEWS

Oxidants and the pathogenesis of lung diseases

(2008) Jonathan Ciencewicki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Respiratory Syncytial Virus Induces RelA Release from Cytoplasmic 100-kDa NF-κB2 Complexes via a Novel Retinoic Acid-inducible Gene-I·NF-κB-inducing Kinase Signaling Pathway

(2008) Ping Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human metapneumovirus: a new respiratory pathogen

(2008) S. Broor et al.   JOURNAL OF BIOSCIENCES

Melatonin decreases TLR3-mediated inflammatory factor expression via inhibition of NF-B activation in respiratory syncytial virus-infected RAW264.7 macrophages

(2008) Sheng-Hai Huang et al.   JOURNAL OF PINEAL RESEARCH

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

Oxygen-Independent Stabilization of Hypoxia Inducible Factor (HIF)-1 during RSV Infection

(2008) Helene A. Haeberle et al.   PLoS One

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

(2008) T. E. Sussan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of human metapneumovirus-induced gene networks in airway epithelial cells by microarray analysis

(2008) X. Bao et al.   VIROLOGY

Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells

(2007) Aruna Kode et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY