Nitro-Fatty Acids: Formation, Redox Signaling, and Therapeutic Potential

Cell signalling by reactive lipid species: new concepts and molecular mechanisms

(2012) Ashlee Higdon et al.   BIOCHEMICAL JOURNAL

Electrophilic Nitro-fatty Acids Activate NRF2 by a KEAP1 Cysteine 151-independent Mechanism

(2011) Emilia Kansanen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nitroarachidonic Acid, a Novel Peroxidase Inhibitor of Prostaglandin Endoperoxide H Synthases 1 and 2

(2011) Andrés Trostchansky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nitro–Fatty Acids Reduce Atherosclerosis in Apolipoprotein E–Deficient Mice

(2010) Tanja K. Rudolph et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nitro-Oleic Acid Inhibits Angiotensin II–Induced Hypertension

(2010) Jifeng Zhang et al.   CIRCULATION RESEARCH

6-Methylnitroarachidonate: A novel esterified nitroalkene that potently inhibits platelet aggregation and exerts cGMP-mediated vascular relaxation

(2010) Fabiana Blanco et al.   FREE RADICAL BIOLOGY AND MEDICINE

Covalent Peroxisome Proliferator-activated Receptor γ Adduction by Nitro-fatty Acids

(2010) Francisco J. Schopfer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH Oxidases: Functions and Pathologies in the Vasculature

(2009) Bernard Lassègue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1

(2009) Aimee L. Eggler et al.   BIOCHEMICAL JOURNAL

Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion

(2009) Volker Rudolph et al.   CARDIOVASCULAR RESEARCH

PPARγ and its ligands: therapeutic implications in cardiovascular disease

(2009) Luis Villacorta et al.   CLINICAL SCIENCE

Detection and quantification of protein adduction by electrophilic fatty acids: mitochondrial generation of fatty acid nitroalkene derivatives

(2009) F.J. Schopfer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2-dependent and -independent Responses to Nitro-fatty Acids in Human Endothelial Cells

(2009) Emilia Kansanen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nitro-fatty Acids Occur in Human Plasma in the Picomolar Range: a Targeted Nitro-lipidomics GC–MS/MS Study

(2009) Dimitrios Tsikas et al.   LIPIDS

Nitrooleic Acid, an Endogenous Product of Nitrative Stress, Activates Nociceptive Sensory Nerves via the Direct Activation of TRPA1

(2009) T. E. Taylor-Clark et al.   MOLECULAR PHARMACOLOGY

Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate

(2008) Ana M. Ferreira et al.   BIOCHEMICAL JOURNAL

Mitochondrial nitroalkene formation and mild uncoupling in ischaemic preconditioning: implications for cardioprotection

(2008) Sergiy M. Nadtochiy et al.   CARDIOVASCULAR RESEARCH

Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

(2008) T. Yamamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular recognition of nitrated fatty acids by PPARγ

(2008) Yong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY