Screening a Repurposing Library for Inhibitors of Multidrug-Resistant Candida auris Identifies Ebselen as a Repositionable Candidate for Antifungal Drug Development

Ebselen Reversibly Inhibits Human Glutamate Dehydrogenase at the Catalytic Site

(2018) Yanhong Jin et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance

(2018) Anuradha Chowdhary et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Ebselen inhibits the activity of acetylcholinesterase globular isoform G4 in vitro and attenuates scopolamine-induced amnesia in mice

(2018) Franciele Martini et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Surface disinfection challenges for Candida auris : an in-vitro study

(2018) R. Kean et al.   JOURNAL OF HOSPITAL INFECTION

Environmental Surfaces in Healthcare Facilities are a Potential Source for Transmission of Candida auris and Other Candida Species

(2017) Christina T. Piedrahita et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Candida auris : An emerging multidrug-resistant pathogen

(2017) David Sears et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Synergistic effect of Ebselen and gamma radiation on breast cancer cells

(2017) Noura M. Thabet et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Survival, Persistence, and Isolation of the Emerging Multidrug-Resistant Pathogenic Yeast Candida auris on a Plastic Health Care Surface

(2017) Rory M. Welsh et al.   JOURNAL OF CLINICAL MICROBIOLOGY

First report of Candida auris in Oman: Clinical and microbiological description of five candidemia cases

(2017) Turkiya Al-Siyabi et al.   JOURNAL OF INFECTION

Safety and efficacy of ebselen for the prevention of noise-induced hearing loss: a randomised, double-blind, placebo-controlled, phase 2 trial

(2017) Jonathan Kil et al.   LANCET

In vitro efficacy of disinfectants utilised for skin decolonisation and environmental decontamination during a hospital outbreak with Candida auris

(2017) Alireza Abdolrasouli et al.   MYCOSES

Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally

(2017) Anuradha Chowdhary et al.   PLoS Pathogens

Current perspective on emergence, diagnosis and drug resistance in Candida auris

(2017) Smita Sarma et al.   Infection and Drug Resistance

Ebselen, a useful tool for understanding cellular redox biology and a promising drug candidate for use in human diseases

(2016) Noriko Noguchi   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Ebselen and analogs as inhibitors of Bacillus anthracis thioredoxin reductase and bactericidal antibacterials targeting Bacillus species, Staphylococcus aureus and Mycobacterium tuberculosis

(2016) Tomas N. Gustafsson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Emergence ofCandida auris: An International Call to Arms

(2016) Cornelius J. Clancy et al.   CLINICAL INFECTIOUS DISEASES

Simultaneous Emergence of Multidrug-ResistantCandida aurison 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses

(2016) Shawn R. Lockhart et al.   CLINICAL INFECTIOUS DISEASES

Ebselen Is a Potential Anti-Osteoporosis Agent by Suppressing Receptor Activator of Nuclear Factor Kappa-B Ligand-Induced Osteoclast Differentiation In vitro and Lipopolysaccharide-Induced Inflammatory Bone Destruction In vivo

(2016) Jong Min Baek et al.   International Journal of Biological Sciences

First report of Candida auris in America: Clinical and microbiological aspects of 18 episodes of candidemia

(2016) Belinda Calvo et al.   JOURNAL OF INFECTION

Can you teach old drugs new tricks?

(2016) Nicola Nosengo   NATURE

Ebselen alters cellular oxidative status and induces endoplasmic reticulum stress in rat hippocampal astrocytes

(2016) Patricia Santofimia-Castaño et al.   TOXICOLOGY

Investigation of the First Seven Reported Cases ofCandida auris,a Globally Emerging Invasive, Multidrug-Resistant Fungus — United States, May 2013–August 2016

(2016) Snigdha Vallabhaneni et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Draft genome of a commonly misdiagnosed multidrug resistant pathogen Candida auris

(2015) Sharanya Chatterjee et al.   BMC GENOMICS

Effect of the Putative Lithium Mimetic Ebselen on Brain Myo-Inositol, Sleep and Emotional Processing in Humans

(2015) Nisha Singh et al.   NEUROPSYCHOPHARMACOLOGY

Repurposing Clinical Molecule Ebselen to Combat Drug Resistant Pathogens

(2015) Shankar Thangamani et al.   PLoS One

Repurposing ebselen for treatment of multidrug-resistant staphylococcal infections

(2015) Shankar Thangamani et al.   Scientific Reports

A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing

(2014) Christopher G Pierce et al.   Nature Protocols

Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target

(2014) Gajendra Kumar Azad et al.   FEBS Open Bio

High-Throughput Screening of a Collection of Known Pharmacologically Active Small Compounds for Identification of Candida albicans Biofilm Inhibitors

(2013) Samuel A. Siles et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antifungal therapy with an emphasis on biofilms

(2013) Christopher G Pierce et al.   CURRENT OPINION IN PHARMACOLOGY

Essential Oils in Combination and Their Antimicrobial Properties

(2012) Imaël Henri Nestor Bassolé et al.   MOLECULES

Antifungal Drug Discovery: Something Old and Something New

(2012) Arielle Butts et al.   PLoS Pathogens

First Three Reported Cases of Nosocomial Fungemia Caused by Candida auris

(2011) Wee Gyo Lee et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Microtiter Dish Biofilm Formation Assay

(2011) George A. O'Toole   Jove-Journal of Visualized Experiments

Candida aurissp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital

(2009) Kazuo Satoh et al.   MICROBIOLOGY AND IMMUNOLOGY

Ciclopirox for the treatment of superficial fungal infections: a review

(2003) Aditya K. Gupta et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY