Contribution of Clinically Derived Mutations inERG11to Azole Resistance in Candida albicans

Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

(2014) B. C. Monk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S279 Point Mutations in Candida albicans Sterol 14-α Demethylase (CYP51) ReduceIn VitroInhibition by Fluconazole

(2012) Andrew G. S. Warrilow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Epidemiology and outcomes of candidemia in 3648 patients: data from the Prospective Antifungal Therapy (PATH Alliance®) registry, 2004–2008

(2012) Michael Pfaller et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Gain-of-Function Mutations in UPC2 Are a Frequent Cause of ERG11 Upregulation in Azole-Resistant Clinical Isolates of Candida albicans

(2012) Stephanie A. Flowers et al.   EUKARYOTIC CELL

The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness inCandida albicans

(2012) Christoph Sasse et al.   MOLECULAR MICROBIOLOGY

Optimization of a molecular mechanics force field for type-II polyoxometalates focussing on electrostatic interactions: A case study

(2011) Blandine Courcot et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Structural differences between soluble and membrane bound cytochrome P450s

(2011) I.G. Denisov et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Amino Acid Substitutions at the Major Insertion Loop of Candida albicans Sterol 14alpha-Demethylase Are Involved in Fluconazole Resistance

(2011) Nidia Alvarez-Rueda et al.   PLoS One

Azole Binding Properties of Candida albicans Sterol 14-  Demethylase (CaCYP51)

(2010) A. G. S. Warrilow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature

(2010) Florent Morio et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Wild-type MIC distributions, epidemiological cutoff values and species-specific clinical breakpoints for fluconazole and Candida: Time for harmonization of CLSI and EUCAST broth microdilution methods

(2010) M.A. Pfaller et al.   DRUG RESISTANCE UPDATES

Oropharyngeal candidiasis in the era of antiretroviral therapy

(2010) George R. Thompson et al.   ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS

The First Virally Encoded Cytochrome P450

(2009) D. C. Lamb et al.   JOURNAL OF VIROLOGY

Investigation of mutations in Erg11 gene of fluconazole resistant Candida albicans isolates from Turkish hospitals

(2009) Lerzan Manastır et al.   MYCOSES

Susceptibility of clinical isolates of Candida species to fluconazole and detection of Candida albicans ERG11 mutations

(2008) Y. Xu et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1

(2008) Anna Selmecki et al.   MOLECULAR MICROBIOLOGY