The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness inCandida albicans

Regulation of Efflux Pump Expression and Drug Resistance by the Transcription Factors Mrr1, Upc2, and Cap1 in Candida albicans

(2011) Sabrina Schubert et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Role of the Npr1 Kinase in Ammonium Transport and Signaling by the Ammonium Permease Mep2 in Candida albicans

(2011) Benjamin Neuhäuser et al.   EUKARYOTIC CELL

A d-octapeptide drug efflux pump inhibitor acts synergistically with azoles in a murine oral candidiasis infection model

(2011) Kazumi Hayama et al.   FEMS MICROBIOLOGY LETTERS

Difference in virulence between fluconazole-susceptible and fluconazole-resistant Candida albicans in a mouse model

(2011) Bettina Schulz et al.   MYCOSES

Contribution of CgPDR1-Regulated Genes in Enhanced Virulence of Azole-Resistant Candida glabrata

(2011) Sélène Ferrari et al.   PLoS One

The Transcription Factor Ndt80 Does Not Contribute to Mrr1-, Tac1-, and Upc2-Mediated Fluconazole Resistance in Candida albicans

(2011) Christoph Sasse et al.   PLoS One

High-Resolution SNP/CGH Microarrays Reveal the Accumulation of Loss of Heterozygosity in Commonly Used Candida albicans Strains

(2011) Darren Abbey et al.   G3-Genes Genomes Genetics

Microarray and Molecular Analyses of the Azole Resistance Mechanism in Candida glabrata Oropharyngeal Isolates

(2010) H.-F. Tsai et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An A643V Amino Acid Substitution in Upc2p Contributes to Azole Resistance in Well-Characterized Clinical Isolates ofCandida albicans

(2010) Samantha J. Hoot et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection

(2010) D. M. MacCallum et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature

(2010) Florent Morio et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Genomewide Expression Profile Analysis of the Candida glabrata Pdr1 Regulon

(2010) Kelly E. Caudle et al.   EUKARYOTIC CELL

Loss of Heterozygosity at an Unlinked Genomic Locus Is Responsible for the Phenotype of a Candida albicans sap4 Δ sap5 Δ sap6 Δ Mutant

(2010) Nico Dunkel et al.   EUKARYOTIC CELL

Persistent Candida albicans colonization and molecular mechanisms of azole resistance in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients

(2010) E. Siikala et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

An A643T Mutation in the Transcription Factor Upc2p Causes Constitutive ERG11 Upregulation and Increased Fluconazole Resistance in Candida albicans

(2009) C. J. Heilmann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Functional Analysis ofcis- andtrans-Acting Elements of theCandida albicans CDR2Promoter with a Novel Promoter Reporter System

(2009) Alix T. Coste et al.   EUKARYOTIC CELL

Widespread occurrence of chromosomal aneuploidy following the routine production ofCandida albicansmutants

(2009) Mélanie Arbour et al.   FEMS YEAST RESEARCH

Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation

(2009) Dominique Sanglard et al.   FEMS YEAST RESEARCH

Regulation of multidrug resistance in pathogenic fungi

(2009) Joachim Morschhäuser   FUNGAL GENETICS AND BIOLOGY

Acquisition of Aneuploidy Provides Increased Fitness during the Evolution of Antifungal Drug Resistance

(2009) Anna M. Selmecki et al.   PLoS Genetics

Gain of Function Mutations in CgPDR1 of Candida glabrata Not Only Mediate Antifungal Resistance but Also Enhance Virulence

(2009) Sélène Ferrari et al.   PLoS Pathogens

Increase of Virulence and Its Phenotypic Traits in Drug-Resistant Strains of Candida albicans

(2008) L. Angiolella et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Gain-of-Function Mutations in the Transcription Factor MRR1 Are Responsible for Overexpression of the MDR1 Efflux Pump in Fluconazole-Resistant Candida dubliniensis Strains

(2008) S. Schubert et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Gain-of-Function Mutation in the Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Increased Fluconazole Resistance in a ClinicalCandida albicansIsolate

(2008) Nico Dunkel et al.   EUKARYOTIC CELL

A New Purple Fluorescent Color Marker for Genetic Studies in Saccharomyces cerevisiae and Candida albicans

(2008) S. Keppler-Ross et al.   GENETICS

Mutations in the multi-drug resistance regulatorMRR1, followed by loss of heterozygosity, are the main cause ofMDR1overexpression in fluconazole-resistantCandida albicansstrains

(2008) Nico Dunkel et al.   MOLECULAR MICROBIOLOGY

An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1

(2008) Anna Selmecki et al.   MOLECULAR MICROBIOLOGY

The ATP-binding cassette transporter–encoding gene CgSNQ2 is contributing to the CgPDR1-dependent azole resistance of Candida glabrata

(2008) Riccardo Torelli et al.   MOLECULAR MICROBIOLOGY

Environmental Induction of White–Opaque Switching in Candida albicans

(2008) Bernardo Ramírez-Zavala et al.   PLoS Pathogens