Review
Infectious Diseases
David Polo, Alberto Lema, Enia Gandara, Jesus L. Romalde
Summary: Through a systematic review and meta-analysis of 35 studies in Europe, it was found that HBoV has a moderate prevalence among European countries, with no significant differences in prevalence by country. The study also analyzed the prevalence of HBoV as a single infection or co-infection with other viruses.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Review
Critical Care Medicine
Marton Papp, Nikolett Kiss, Mate Baka, Domonkos Trasy, Laszlo Zubek, Peter Fehervari, Andrea Harnos, Caner Turan, Peter Hegyi, Zsolt Molnar
Summary: PCT-guided antibiotic therapy may reduce antibiotic use and lower 28-day mortality, but may increase the risk of infection recurrence. However, there are no significant differences in ICU and hospital length of stay. Better-designed studies are needed to further investigate the role of PCT-guided antibiotic stewardship in critically ill patients.
Review
Food Science & Technology
Maciej Halasa, Magdalena Baskiewicz-Halasa, Dominika Jamiol-Milc, Dominika Maciejewska-Markiewicz, Karolina Skonieczna-Zydecka
Summary: The study found that bovine colostrum supplementation (BCS) can effectively prevent upper respiratory tract infections (URTIs) and reduce the incidence rate. The effectiveness of BCS is somewhat dependent on the duration of supplementation, but not on the dose size, sex distribution, or physical activity lifestyle.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Review
Nutrition & Dietetics
Yihan Zhang, Yifei Lu, Shaokang Wang, Ligang Yang, Hui Xia, Guiju Sun
Summary: The study reveals that there were no additional benefits of vitamin A supplementation in preventing or recovering from acute respiratory infections in children. Excessive vitamin A supplementation might actually increase the incidence of ARTI in well-nourished children.
Review
Allergy
Berber Vlieg-Boerstra, Nicolette de Jong, Rosan Meyer, Carlo Agostoni, Valentina De Cosmi, Kate Grimshaw, Gregorio Paolo Milani, Antonella Muraro, Hanneke Oude Elberink, Isabella Pali-Scholl, Caroline Roduit, Mari Sasaki, Isabel Skypala, Milena Sokolowska, Marloes van Splunter, Eva Untersmayr, Carina Venter, Liam O'Mahony, Bright Nwaru
Summary: Nutrient supplementation for the general population appears to have limited effectiveness in preventing respiratory tract infections, with zinc supplementation showing potential protective effects in children in Asia and vitamin D supplementation reducing the incidence of RTIs in adults in North America.
Review
Pharmacology & Pharmacy
Rixiang Xu, Lang Wu, Lingyun Wu, Caiming Xu, Tingyu Mu
Summary: Clinical decision support tools effectively reduce inappropriate antibiotic use for respiratory tract infections among physicians, but interventions lasting more than 2 years do not yield significant effects.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Public, Environmental & Occupational Health
Thibault Lovey, Robin Hasler, Philippe Gautret, Patricia Schlagenhauf
Summary: This systematic review and meta-analysis aims to evaluate the prevalence of respiratory tract infections (RTIs) and symptoms among travellers, and to describe the spectrum of RTIs. The findings show a high burden of RTIs among travellers, reflecting respiratory infection outbreaks. These findings have important implications for understanding and managing RTIs among travellers.
JOURNAL OF TRAVEL MEDICINE
(2023)
Review
Urology & Nephrology
Guobin Su, Masao Iwagami, Xindong Qin, Helen McDonald, Xusheng Liu, Juan Jesus Carrero, Cecilia Stalsby Lundborg, Dorothea Nitsch
Summary: The presence of kidney disease is associated with higher mortality in patients with respiratory tract infections, especially pneumonia. Nearly all studies showed a positive association between underlying chronic kidney disease and mortality, with the risk almost doubling in patients with kidney disease.
CLINICAL KIDNEY JOURNAL
(2021)
Review
Infectious Diseases
Ashley Hammond, Alice Halliday, Hannah Thornton, Alastair D. Hay
Summary: This study identified modifiable risk factors associated with increased likelihood of acquiring respiratory tract infections in the community, including low BMI, contact with children and pets. Modification of these risk factors and increased awareness of vulnerable groups could help reduce morbidity, mortality, and antibiotic use associated with respiratory tract infections.
BMC INFECTIOUS DISEASES
(2021)
Review
Nutrition & Dietetics
Bronwyn S. Berthon, Lily M. Williams, Evan J. Williams, Lisa G. Wood
Summary: Lactoferrin supplementation may have beneficial effects on inflammation, immune function, and respiratory tract infections, but clinical studies are limited and further research is needed.
ADVANCES IN NUTRITION
(2022)
Review
Medicine, General & Internal
Ye Tian, Lie Wang, Zhongtian Wang, Lizhong Ding, Lina Wei, Lei Guo, Xiaozhou Sun, Lei Wang, Fushuang Yang, Liping Sun
Summary: Recurrent respiratory tract infections are common respiratory ailments in children that can have a significant impact on their physical and mental health. This study aims to evaluate the efficacy and safety of Tuina massage in treating RRTIs.
Review
Public, Environmental & Occupational Health
Jia Yao, Yuan Zhang, Xian-Zhe Wang, Jia Zhao, Zhao-Jun Yang, Yu-Ping Lin, Lu Sun, Qi-Yun Lu, Guan-Jie Fan
Summary: The systematic review and meta-analysis showed that flavonoids are effective and safe in treating viral acute respiratory tract infections. However, the conclusions should be confirmed in larger-scale studies due to limitations in the number and quality of the included trials.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Infectious Diseases
Mona Mustafa Hellou, Anna Gorska, Fulvia Mazzaferri, Eleonora Cremonini, Elisa Gentilotti, Pasquale De Nardo, Itamar Poran, Mariska M. Leeflang, Evelina Tacconelli, Mical Paul
Summary: This study evaluated the diagnostic test accuracy of nucleic acid amplification tests (NAATs) for coronavirus infections and found that real-time RT-PCR assays have higher sensitivity. The pooled results indicated that on average 10% of patients with coronavirus infections might be missed with PCR tests.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Review
Pediatrics
Lu Zhang, Xuqiong Wang, Dong Wang, Yinling Guo, Xinying Zhou, Haiyan Yu
Summary: This study demonstrated that adjuvant YPFG therapy can improve clinical response rate and increase serum immunoglobulin levels while decreasing TNF-alpha level in children with recurrent respiratory tract infections.
FRONTIERS IN PEDIATRICS
(2022)
Review
Virology
Rohin K. Reddy, Walton N. Charles, Alexandros Sklavounos, Atul Dutt, Paul T. Seed, Ankur Khajuria
Summary: Smoking is associated with increased risk of severe COVID-19 and worse in-hospital outcomes, as current smokers and patients with a smoking history are more susceptible to severe disease and have higher mortality rates.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Respiratory System
Feng-Jia Chen, Huai Liao, Xin-Yan Huang, Can-Mao Xie
JOURNAL OF THORACIC DISEASE
(2016)
Article
Respiratory System
Xin Zhang, Yukun Kuang, Yuan Zhang, Kai He, Noah Lechtzin, Mingying Zeng, Rex C. Yung, Canmao Xie
JOURNAL OF THORACIC DISEASE
(2016)
Article
Respiratory System
Nanshan Zhong, Jiangtao Lin, Jinping Zheng, Kefang Lai, Canmao Xie, Ke-Jing Tang, Mao Huang, Ping Chen, Changzheng Wang
THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE
(2016)
Article
Oncology
Xiaoran Liu, Yangli Liu, Xinyan Huang, Gengpeng Lin, Canmao Xie
MOLECULAR MEDICINE REPORTS
(2017)
Article
Medicine, General & Internal
Y. Zhou, N. Zhong, Xiaochen Li, S. Chen, J. Zheng, D. Zhao, W. Yao, R. Zhi, L. Wei, B. He, X. Zhang, C. Yang, Ying Li, F. Li, J. Du, J. Gui, B. Hu, C. Bai, P. Huang, G. Chen, Y. Xu, C. Wang, B. Liang, Yinhuan Li, G. Hu, H. Tan, X. Ye, X. Ma, Y. Chen, X. Hu, J. Tian, X. Zhu, Z. Shi, X. Du, M. Li, S. Liu, R. Yu, J. Zhao, Q. Ma, C. Xie, Xiongbin Li, T. Chen, Y. Lin, Lizhen Zeng, C. Ye, W. Ye, X. Luo, Lingshan Zeng, S. Yu, W. Guan, P. Ran
NEW ENGLAND JOURNAL OF MEDICINE
(2017)
Article
Respiratory System
Yu-Dong Yin, Rui Wang, Chao Zhuo, Hui Wang, Ming-Gui Wang, Can-Mao Xie, Dan-Yang She, Xin Yuan, Ren-Tao Wang, Bin Cao, You-Ning Liu
JOURNAL OF THORACIC DISEASE
(2017)
Article
Pathology
Gengpeng Lin, Hui Li, Jianyi Kuang, Kejing Tang, Yubiao Guo, Anjia Han, Canmao Xie
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
(2018)
Article
Medicine, General & Internal
Hongchun Du, Yubiao Guo, Di Ma, Kejing Tang, Decheng Cai, Yifeng Luo, Canmao Xie
Article
Oncology
Jian Zhang, Chang Zou, Chenzhi Zhou, Yifeng Luo, Qiong He, Yu Sun, Jianwen Zhou, Zunfu Ke
JOURNAL OF THORACIC ONCOLOGY
(2020)
Review
Medicine, Research & Experimental
Boxuan Huang, Rongsong Ling, Yifan Cheng, Jieqi Wen, Yarong Dai, Wenjie Huang, Siyan Zhang, Xifeng Lu, Yifeng Luo, Yi-Zhou Jiang
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT
(2020)
Article
Infectious Diseases
Yangli Liu, Weiping Tan, Haihong Chen, Ying Zhu, Li Wan, Ke Jiang, Yubiao Guo, Kejing Tang, Canmao Xie, Hui Yi, Yukun Kuang, Yifeng Luo
Summary: A sustained decrease in lymphocyte subsets, especially CD4(+) T cells and NK cells, interacting with proinflammatory cytokine storms was associated with severe disease and poor prognosis in COVID-19.
BMC INFECTIOUS DISEASES
(2021)
Article
Biochemistry & Molecular Biology
Yifeng Luo, Gang Niu, Hui Yi, Qingling Li, Zhiqiang Wu, Jing Wang, Juan Yang, Bo Li, Yuan Peng, Ying Liang, Weiwei Wang, Zhenwei Peng, Xintao Shuai, Yu Guo
Summary: miR-101?3p restores ferroptosis in tumor cells by targeting TBLR1, promoting apoptosis and inhibiting proliferation. Nanomedicine can deliver miR-101?3p to tumor cells for ferroptosis recovery, potentially serving as an effective therapy to inhibit tumor proliferation.
Article
Physiology
Yifeng Luo, Hui Yi, Xinyan Huang, Gengpeng Lin, Yukun Kuang, Yubiao Guo, Canmao Xie
Summary: MIF inhibition by gene knockdown significantly inhibits lung inflammation and fibrosis in rats with bleomycin-induced pulmonary fibrosis.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Qi Zhao, Yi-Feng Luo, Mi Tian, Yong-Long Xiao, Hou-Rong Cai, Hui Li
Summary: Pseudomonas aeruginosa induces macrophage senescence, which is regulated by the expression level of activating transcription factor 3 (ATF3). Manipulation of ATF3 expression affects macrophage senescence and phagocytic capacity, possibly through modulation of NF-kappa B translocation and inflammatory cytokine production.
MOLECULAR IMMUNOLOGY
(2021)
Article
Infectious Diseases
Jianhong Kang, Ting Chen, Honghe Luo, Yifeng Luo, Guipeng Du, Mia Jiming-Yang
Summary: A predictive model for severe COVID-19 in patients was developed using clinical data from 151 cases, with features like ALB, GLB, and BUN showing correlations with severity. The neural network model achieved good prediction performance, indicating potential risk factors for severe COVID-19 and providing significance in early clinical interventions and improving cure rates.
INFECTION GENETICS AND EVOLUTION
(2021)