Hearing Loss: Mechanisms Revealed by Genetics and Cell Biology

Candidate Gene Association Study for Noise-induced Hearing Loss in Two Independent Noise-exposed Populations

(2009) A. Konings et al.   ANNALS OF HUMAN GENETICS

The Functional Annotation of Mammalian Genomes: The Challenge of Phenotyping

(2009) Steve D.M. Brown et al.   Annual Review of Genetics

Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice

(2009) Garrett A. Soukup et al.   DEVELOPMENTAL BIOLOGY

Genetic Studies on Noise-Induced Hearing Loss: A Review

(2009) Annelies Konings et al.   EAR AND HEARING

Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments

(2009) Felipe T. Salles et al.   NATURE CELL BIOLOGY

Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss

(2009) Ángeles Mencía et al.   NATURE GENETICS

An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice

(2009) Morag A Lewis et al.   NATURE GENETICS

Functional Studies Reveal New Mechanisms for Deafness Caused by Connexin Mutations

(2009) Qing Chang et al.   OTOLOGY & NEUROTOLOGY

Deafness Genes in Israel: Implications for Diagnostics in the Clinic

(2009) Zippora Brownstein et al.   PEDIATRIC RESEARCH

Unraveling cadherin 23's role in development and mechanotransduction

(2009) J.-B. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs are essential for development and function of inner ear hair cells in vertebrates

(2009) L. M. Friedman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lineage-Specific Biology Revealed by a Finished Genome Assembly of the Mouse

(2009) Deanna M. Church et al.   PLOS BIOLOGY

A novel nonsense mutation inMYO6is associated with progressive nonsyndromic hearing loss in a DanishDFNA22family

(2008) Kirsten M. Sanggaard et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A Novel SLC26A4 (PDS) Deafness Mutation Retained in the Endoplasmic Reticulum

(2008) Zippora N. Brownstein et al.   ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

The Kinase Domain Alters the Kinetic Properties of the Myosin IIIA Motor†

(2008) Andréa C. Dosé et al.   BIOCHEMISTRY

Impacts of Usher Syndrome Type IB Mutations on Human Myosin VIIa Motor Function†

(2008) Shinya Watanabe et al.   BIOCHEMISTRY

The tectorial membrane: one slice of a complex cochlear sandwich

(2008) Guy P Richardson et al.   Current Opinion in Otolaryngology & Head and Neck Surgery

Differentiation of inner ear stem cells to functional sensory neurons

(2008) Rodrigo Martinez-Monedero et al.   Developmental Neurobiology

A splice-site mutation and overexpression of MYO6 cause a similar phenotype in two families with autosomal dominant hearing loss

(2008) Nele Hilgert et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Forty-six genes causing nonsyndromic hearing impairment: Which ones should be analyzed in DNA diagnostics?

(2008) Nele Hilgert et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer

(2008) Samuel P. Gubbels et al.   NATURE

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions

(2008) Elisabeth Verpy et al.   NATURE

Gap Junction Mediated Intercellular Metabolite Transfer in the Cochlea Is Compromised in Connexin30 Null Mice

(2008) Qing Chang et al.   PLoS One

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear

(2008) F. Anselmi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinated control of connexin 26 and connexin 30 at the regulatory and functional level in the inner ear

(2008) S. Ortolano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene Regulation by Transcription Factors and MicroRNAs

(2008) O. Hobert   SCIENCE

Dynamic length regulation of sensory stereocilia

(2008) U MANOR et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Pendred syndrome and iodide transport in the thyroid

(2008) Peter Kopp et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The impact of next-generation sequencing technology on genetics

(2008) Elaine R. Mardis   TRENDS IN GENETICS

A Myo6 Mutation Destroys Coordination between the Myosin Heads, Revealing New Functions of Myosin VI in the Stereocilia of Mammalian Inner Ear Hair Cells

(2008) Ronna Hertzano et al.   PLoS Genetics

Usher syndrome: Animal models, retinal function of Usher proteins, and prospects for gene therapy

(2007) David S. Williams   VISION RESEARCH