Recent Advances in Magnetic Tweezers

Counting proteins bound to a single DNA molecule

(2011) John S. Graham et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanical Load Induces a 100-Fold Increase in the Rate of Collagen Proteolysis by MMP-1

(2011) Arjun S. Adhikari et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Parallel Magnetic Tweezers by Targeted DNA Tethering

(2011) Iwijn De Vlaminck et al.   NANO LETTERS

Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques

(2011) J. T. Holthausen et al.   NUCLEIC ACIDS RESEARCH

Combining optical trapping, fluorescence microscopy and micro-fluidics for single molecule studies of DNA–protein interactions

(2011) Andrea Candelli et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase

(2011) H. Bai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Soft magnetic tweezers: A proof of principle

(2011) Francesco Mosconi et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

A method to track rotational motion for use in single-molecule biophysics

(2011) Jan Lipfert et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Single-Base Pair Unwinding and Asynchronous RNA Release by the Hepatitis C Virus NS3 Helicase

(2011) W. Cheng et al.   SCIENCE

Freely orbiting magnetic tweezers to directly monitor changes in the twist of nucleic acids

(2011) Jan Lipfert et al.   Nature Communications

Quantitative Guidelines for Force Calibration through Spectral Analysis of Magnetic Tweezers Data

(2010) Aartjan J.W. te Velthuis et al.   BIOPHYSICAL JOURNAL

Cellular Strategies for Regulating DNA Supercoiling: A Single-Molecule Perspective

(2010) Daniel A. Koster et al.   CELL

Magnetic torque tweezers: measuring torsional stiffness in DNA and RecA-DNA filaments

(2010) Jan Lipfert et al.   NATURE METHODS

Active and passive mechanisms of helicases

(2010) Maria Manosas et al.   NUCLEIC ACIDS RESEARCH

Modulation of HU–DNA interactions by salt concentration and applied force

(2010) Botao Xiao et al.   NUCLEIC ACIDS RESEARCH

Torsional regulation of hRPA-induced unwinding of double-stranded DNA

(2010) Iwijn De Vlaminck et al.   NUCLEIC ACIDS RESEARCH

Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA

(2010) J. S. Graham et al.   NUCLEIC ACIDS RESEARCH

Real-time particle tracking at 10,000 fps using optical fiber illumination

(2010) Oliver Otto et al.   OPTICS EXPRESS

Type III restriction enzymes cleave DNA by long-range interaction between sites in both head-to-head and tail-to-tail inverted repeat

(2010) K. van Aelst et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minute negative superhelicity is sufficient to induce the B-Z transition in the presence of low tension

(2010) M. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical Characterization of Protein L in the Low-Force Regime by Electromagnetic Tweezers/Evanescent Nanometry

(2009) Ruchuan Liu et al.   BIOPHYSICAL JOURNAL

Quantitative Modeling and Optimization of Magnetic Tweezers

(2009) Jan Lipfert et al.   BIOPHYSICAL JOURNAL

Magnetic Tweezers Measurement of Single Molecule Torque

(2009) Alfredo Celedon et al.   NANO LETTERS

Single-molecule force spectroscopy reveals a highly compliant helical folding for the 30-nm chromatin fiber

(2009) Maarten Kruithof et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamics of RecA filaments on single-stranded DNA

(2009) Marijn T. J. van Loenhout et al.   NUCLEIC ACIDS RESEARCH

A high-resolution magnetic tweezer for single-molecule measurements

(2009) Kipom Kim et al.   NUCLEIC ACIDS RESEARCH

Torsional Stiffness of Single Superparamagnetic Microspheres in an External Magnetic Field

(2009) Daniel Klaue et al.   PHYSICAL REVIEW LETTERS

Measurement of the Torque on a Single Stretched and Twisted DNA Using Magnetic Tweezers

(2009) Francesco Mosconi et al.   PHYSICAL REVIEW LETTERS

Direct observation of twisting steps during Rad51 polymerization on DNA

(2009) H. Arata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type III restriction enzymes communicate in 1D without looping between their target sites

(2009) Subramanian P. Ramanathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic position and force measurement for multiple optically trapped particles using a high-speed active pixel sensor

(2009) M. Towrie et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Recent Advances in Optical Tweezers

(2008) Jeffrey R. Moffitt et al.   Annual Review of Biochemistry

Advances in Single-Molecule Fluorescence Methods for Molecular Biology

(2008) Chirlmin Joo et al.   Annual Review of Biochemistry

Fluorescence Proteins, Live-Cell Imaging, and Mechanobiology: Seeing Is Believing

(2008) Yingxiao Wang et al.   Annual Review of Biomedical Engineering

Controlled torque on superparamagnetic beads for functional biosensors

(2008) X.J.A. Janssen et al.   BIOSENSORS & BIOELECTRONICS

Homologous Recombination in Real Time: DNA Strand Exchange by RecA

(2008) Thijn van der Heijden et al.   MOLECULAR CELL

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

(2008) Keir C Neuman et al.   NATURE METHODS

DNA torsional stress propagates through chromatin fiber and participates in transcriptional regulation

(2008) Christophe Lavelle   NATURE STRUCTURAL & MOLECULAR BIOLOGY

See me, feel me: methods to concurrently visualize and manipulate single DNA molecules and associated proteins

(2008) J. van Mameren et al.   NUCLEIC ACIDS RESEARCH

Calibration of dynamic holographic optical tweezers for force measurements on biomaterials

(2008) Astrid van der Horst et al.   OPTICS EXPRESS

Maxwell relations for single-DNA experiments: Monitoring protein binding and double-helix torque with force-extension measurements

(2008) Houyin Zhang et al.   PHYSICAL REVIEW E

Abrupt Buckling Transition Observed during the Plectoneme Formation of Individual DNA Molecules

(2008) Scott Forth et al.   PHYSICAL REVIEW LETTERS

Multiplexed single-molecule measurements with magnetic tweezers

(2008) Noah Ribeck et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Optical tweezers with 2.5 kHz bandwidth video detection for single-colloid electrophoresis

(2008) Oliver Otto et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Subpiconewton Dynamic Force Spectroscopy Using Magnetic Tweezers

(2007) M. Kruithof et al.   BIOPHYSICAL JOURNAL