Article
Biophysics
Qiong Wang, Jing Wang, Yan Huang, Yichen Du, Yi Zhang, Yunxi Cui, De-ming Kong
Summary: Molecular biomarkers are crucial for disease diagnosis and biological research, with DNA-based biosensors emerging as versatile tools for their detection. The development of highly efficient probes for biomarker detection is an attractive research field, especially in the context of urgent demands for improved biosensor performance in clinical applications. The rapid and sensitive detection methods developed in response to the COVID-19 pandemic showcase the importance of DNA-based biosensors in advancing disease diagnosis and treatment.
BIOSENSORS & BIOELECTRONICS
(2022)
Review
Health Care Sciences & Services
Laure Abensur Vuillaume, Justine Frija-Masson, Meriem Hadjiat, Thomas Riquier, Marie-Pia D'ortho, Pierrick Le Borgne, Christophe Goetz, Paul L. Voss, Abdallah Ougazzaden, Jean-Paul Salvestrini, Thierry Leichle
Summary: This article discusses the relevance of obtaining specific biomarkers in emergency situations, particularly in relation to cardiovascular disease. It highlights the potential of biosensors to meet the need for rapid biological analysis in medical settings and addresses market access issues.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Biotechnology & Applied Microbiology
Jian Shi, Xingmei Li, Maria Jose Cavagnaro, Jifeng Cai, Changquan Zhang, Na Li
Summary: The study introduces a highly efficient system for the early diagnosis of mild traumatic brain injury (mTBI) using a molecular biomarker. The system utilizes a low cytotoxic peptide-modified fluorescent nanoprobe based on carbon polymer dots, showing excellent imaging capabilities in both in vitro and in vivo tests. Additionally, the system's successful detection of the mTBI biomarker in mouse models and human blood samples suggests its potential as a sensitive, rapid, non-toxic, and reliable diagnostic tool for mTBI.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Ganganath S. Perera, Taimur Ahmed, Leah Heiss, Sumeet Walia, Madhu Bhaskaran, Sharath Sriram
Summary: Metal oxide based sensors can rapidly and accurately detect biomarkers with high selectivity and sensitivity. Through short incubation times and real-time monitoring through electrical measurements, biomarkers can be detected at concentrations lower than healthy levels, with strong selectivity for the target biomarkers.
Article
Engineering, Environmental
Meng Shien Goh, Su Datt Lam, YaFeng Yang, Mohd Naqiuddin, Siti Nor Khadijah Addis, Wilson Thau Lym Yong, Vijitra Luang-In, Christian Sonne, Nyuk Ling Ma
Summary: The use of chemical pesticides in agriculture is convenient and effective, but may pose risks to human health and the environment through residue contamination. Developing biosensors for on-site detection and promoting alternative pesticides like biopesticides and nanopesticides are recommended, though safety assessments are essential. Reversing pesticide application trends based on changing climate conditions is urgent for sustainable farming practices.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Review
Chemistry, Analytical
Azam Ahangari, Pezhman Mahmoodi, Abdolmajid Mohammadzadeh
Summary: Brucellosis is a challenging disease to detect, especially in developing countries. Traditional diagnostic methods are time-consuming, expensive, and require special equipment, thus there is a need for the development of rapid and simple detection methods. Nanotechnology offers a potential solution, with nanobiosensors being a promising tool.
MICROCHEMICAL JOURNAL
(2022)
Article
Spectroscopy
Xuhua Zhao, Xiaochun Dai, Suya Zhao, Xiaohua Cui, Tao Gong, Zhiling Song, Hongmin Meng, Xiaobing Zhang, Baofeng Yu
Summary: Aptamers, as short single-stranded RNA or DNA molecules that can recognize targets with high affinity and specificity, have unique advantages such as easy chemical synthesis, high stability, low molecular weight, and lack of immunogenicity. Utilizing aptamers in fluorescent sensors provides exciting opportunities for sensitive detection and quantification of analytes, particularly in the field of cancer biomarker detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Review
Chemistry, Multidisciplinary
Changhao Dai, Derong Kong, Chang Chen, Yunqi Liu, Dacheng Wei
Summary: Biomarkers are vital for accurate diagnosis and treatment. Graphene field-effect transistor (GFET) biosensors have demonstrated significant advantages, such as fast response time, high sensitivity, easy operation, integration capability, and label-free detection. This review summarizes the latest advancements in GFET biosensors, including device design, working principle, surface functionalization, and proof-of-concept applications. The article also discusses the ongoing research efforts and future prospects for the development of GFET sensor systems.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Biophysics
Veronika Vanova, Katerina Mitrevska, Vedran Milosavljevic, David Hynek, Lukas Richtera, Vojtech Adam
Summary: This article discusses the detection of protein biomarkers, focusing on the potential of peptides combined with electrochemical biosensors, as well as the detection methods and sensing mechanisms for different types of proteins.
BIOSENSORS & BIOELECTRONICS
(2021)
Review
Engineering, Electrical & Electronic
Fareeha Arshad, Damien W. M. Arrigan, Minhaz Uddin Ahmed
Summary: This article presents the recent advances in nanozyme based biosensors and discusses the challenges in this field. Studies have shown that synthetic enzyme-based biosensors can effectively detect various clinical biomarkers, thus having the potential to replace conventional testing methods.
IEEE SENSORS JOURNAL
(2022)
Review
Biochemical Research Methods
Yousef Rasmi, Xiaokang Li, Johra Khan, Tugba Ozer, Jane Ru Choi
Summary: The COVID-19 pandemic poses a serious global health threat and there is an urgent need for rapid and user-friendly diagnostic tools. Point-of-care biosensors, including chip-based and paper-based biosensors, offer a promising solution for remote and resource-limited settings due to their rapid, affordable, and portable nature. The review highlights the importance of early diagnosis of COVID-19 and discusses the advancements in POC biosensors categorized into chip-based, paper-based, and other biosensors, with a focus on detecting key biomarkers. The commercial POC biosensors for COVID-19 are critically evaluated, along with key challenges and future perspectives in developing these emerging technologies.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Rajendra P. Shukla, Matan Aroosh, Alon Matzafi, Hadar Ben-Yoav
Summary: This study introduces a novel sensing electrodes array modified with biopolymer chitosan and electrocatalytic carbon nanotube films for rapid analysis of neurotransmitter dopamine levels in urine. The feasibility of quantifying dopamine levels from unprocessed urine samples is demonstrated, potentially providing better tools for differentiating redox molecules in highly complex biofluids.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Review
Chemistry, Analytical
Zhi-Fang Sun, Yong Chang, Ning Xia
Summary: This review summarizes the recent development of nanomaterials-based optical and electrochemical analytical techniques for CTCs detection, aiming at amplifying the signal and enhancing the sensitivity.
Review
Chemistry, Physical
Muthusankar Eswaran, Bavatharani Chokkiah, Santosh Pandit, Shadi Rahimi, Ragupathy Dhanusuraman, Mahaboobbatcha Aleem, Ivan Mijakovic
Summary: Field effect transistor (FET)-based nanoelectronic biosensors provide a viable route for cancer biomarker detection. Researchers have made significant efforts to address issues such as sensitivity, selectivity, and operational conditions to improve the sensing performance of FETs. This review discusses the fabrication of FETs, choice of bioreceptors, operational conditions, and strategies for improving the sensing performance of FET-based diagnostic devices.
Article
Food Science & Technology
Alessia Cossettini, Jasmina Vidic, Michela Maifreni, Marilena Marino, Debora Pinamonti, Marisa Manzano
Summary: Listeria, Campylobacter, Salmonella, and Escherichia coli are common causes of foodborne disease in humans, making early and rapid detection crucial for food safety. Recently reported biosensors have shown superior performance in terms of speed, selectivity, sensitivity, and affordability compared to conventional microbiological methods for detecting these bacteria in food.
Article
Microbiology
Tomasz A. Leski, Rashid Ansumana, Chris R. Taitt, Joseph M. Lamin, Umaru Bangura, Joseph Lahai, George Mbayo, Mohamed B. Kanneh, Ben Bawo, Alfred S. Bockarie, Matt Scullion, Cynthia L. Phillips, Cynthia P. Horner, Kathryn H. Jacobsen, David A. Stenger
JOURNAL OF CLINICAL MICROBIOLOGY
(2015)
Article
Microbiology
Tomasz A. Leski, Michael G. Stockelman, Umaru Bangura, Daniel Chae, Rashid Ansumana, David A. Stenger, Gary J. Vora, Chris R. Taitt
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2016)
Article
Biophysics
Chris Rowe Taitt, George P. Anderson, Frances S. Ligler
BIOSENSORS & BIOELECTRONICS
(2016)
Article
Infectious Diseases
Tomasz A. Leski, Chris R. Taitt, Umaru Bangura, Michael G. Stockelman, Rashid Ansumana, William H. Cooper, David A. Stenger, Gary J. Vora
BMC INFECTIOUS DISEASES
(2016)
Article
Chemistry, Multidisciplinary
Lisa C. Shriver-Lake, George P. Anderson, Chris Rowe Taitt
Article
Multidisciplinary Sciences
Chris Rowe Taitt, Tomasz A. Leski, Daniel P. Erwin, Elizabeth A. Odundo, Nancy C. Kipkemoi, Janet N. Ndonye, Ronald K. Kirera, Abigael N. Ombogo, Judd L. Walson, Patricia B. Pavlinac, Christine Hulseberg, Gary J. Vora
Article
Multidisciplinary Sciences
Chenyue Wang, Janna N. Schultzhaus, Chris R. Taitt, Dagmar H. Leary, Lisa C. Shriver-Lake, Daniel Snellings, Samantha Sturiale, Stella H. North, Beatriz Orihuela, Daniel Rittschof, Kathryn J. Wahl, Christopher M. Spillmann
Article
Biochemical Research Methods
Chris R. Taitt, Tomasz A. Leski, Sophie M. Colston, Manuela Bernal, Enrique Canal, James Regeimbal, Paul Rios, Gary J. Vora
ANALYTICAL BIOCHEMISTRY
(2019)
Article
Biochemical Research Methods
Janna N. Schultzhaus, Chris R. Taitt, Beatriz Orihuela, Madeline Smerchansky, Zachary S. Schultzhaus, Daniel Rittschof, Kathryn J. Wahl, Christopher M. Spillmann
ANALYTICAL BIOCHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Chris R. Taitt, Tomasz A. Leski, Amy Chen, Kimberly L. Berk, Robert W. Dorsey, Michael J. Gregory, Shanmuga Sozhamannan, Kenneth G. Frey, Diane L. Dutt, Gary J. Vora
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Infectious Diseases
Tomasz A. Leski, Chris Rowe Taitt, Abdulai G. Swaray, Umaru Bangura, Nathanael D. Reynolds, Andrew Holtz, Chadwick Yasuda, Joseph Lahai, Joseph M. Lamin, Victoria Baio, Kathryn H. Jacobsen, Rashid Ansumana, David A. Stenger
Article
Biochemistry & Molecular Biology
Chris R. Taitt, Tomasz A. Leski, Michael G. Prouty, Gavin W. Ford, Vireak Heang, Brent L. House, Samuel Y. Levin, Jennifer A. Curry, Adel Mansour, Hanan El Mohammady, Momtaz Wasfy, Drake Hamilton Tilley, Michael J. Gregory, Matthew R. Kasper, James Regeimbal, Paul Rios, Guillermo Pimentel, Brook A. Danboise, Christine E. Hulseberg, Elizabeth A. Odundo, Abigael N. Ombogo, Erick K. Cheruiyot, Cliff O. Philip, Gary J. Vora
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Chemistry, Analytical
Shawn P. Mulvaney, Lisa A. Fitzgerald, Leila J. Hamdan, Bradley R. Ringeisen, Emily R. Petersen, Jaimee R. Compton, Nina L. McAuliff, Tomasz A. Leski, Chris R. Taitt, David A. Stenger, Christopher A. Myers, Erin Hansen, Michelle Ricketts, Chelsea Hoegberg, Kamonthip Homdayjanakul, Rashid Ansumana, Joseph M. Lamin, Umaru Bangura, Joseph Lahai, Victoria Baio, Direk Limmathurotsakul, Gumphol Wongsuvan, Viriya Hantrakun, Supaporn Wacharapluesadee, Anek Mungaomklang, Opass Putcharoen, Pratoomtong Yatoom, Kriengsak Kruthakool, Robert D. Hontz, Christopher Mores, Crystyan Siles, Amy Morrison, Mark Mayo, Bart J. Currie, Kathryn H. Jacobsen, Kathleen Quinn, Jerold Blutman, Flavia Amariei, John Hannan
SENSING AND BIO-SENSING RESEARCH
(2018)
Article
Public, Environmental & Occupational Health
Donald F. Dariano, Chris R. Taitt, Kathryn H. Jacobsen, Umaru Bangura, Alfred S. Bockarie, Moses J. Bockarie, Joseph Lahai, Joseph M. Lamin, Tomasz A. Leski, Chadwick Yasuda, David A. Stenger, Rashid Ansumana
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2017)
Article
Microbiology
Tomasz A. Leski, Chris R. Taitt, Umaru Bangura, Rashid Ansumana, David A. Stenger, Zheng Wang, Gary J. Vora
GENOME ANNOUNCEMENTS
(2016)