Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis

THU0057 Inhibition of Heat Shock Protein 90 (Hsp90) Prevents Fibrosis by Targeting Canonical TGF-B Signaling

(2014) M. Tomcik et al.   ANNALS OF THE RHEUMATIC DISEASES

Activation of pregnane X receptor inhibits experimental dermal fibrosis

(2013) Christian Beyer et al.   ANNALS OF THE RHEUMATIC DISEASES

Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis

(2013) Christian Beyer et al.   ANNALS OF THE RHEUMATIC DISEASES

Kinase CK2 Inhibition: An Update

(2013) G. Cozza et al.   CURRENT MEDICINAL CHEMISTRY

Inhibition of sumoylation prevents experimental fibrosis

(2012) Aisa Khodzhigorova et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis

(2012) Angelika Horn et al.   ANNALS OF THE RHEUMATIC DISEASES

Stimulation of soluble guanylate cyclase reduces experimental dermal fibrosis

(2012) Christian Beyer et al.   ANNALS OF THE RHEUMATIC DISEASES

Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis

(2012) Nicole Reich et al.   ANNALS OF THE RHEUMATIC DISEASES

Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1

(2012) Katrin Palumbo-Zerr et al.   ANNALS OF THE RHEUMATIC DISEASES

Pomalidomide is effective for prevention and treatment of experimental skin fibrosis

(2012) Simon Weingärtner et al.   ANNALS OF THE RHEUMATIC DISEASES

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

(2012) Christian Beyer et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis

(2012) Marlene Krämer et al.   ANNALS OF THE RHEUMATIC DISEASES

JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis

(2012) Clara Dees et al.   ARTHRITIS AND RHEUMATISM

TGF-β signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities

(2012) Rohan Samarakoon et al.   CELLULAR SIGNALLING

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

The transcription factor JunD mediates transforming growth factor  -induced fibroblast activation and fibrosis in systemic sclerosis

(2011) K. Palumbo et al.   ANNALS OF THE RHEUMATIC DISEASES

Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis

(2011) C. Dees et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis

(2011) Jérôme Avouac et al.   ARTHRITIS AND RHEUMATISM

A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway

(2011) Y. Zheng et al.   BLOOD

Platelet-derived serotonin links vascular disease and tissue fibrosis

(2011) Clara Dees et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database

(2010) A. J. Tyndall et al.   ANNALS OF THE RHEUMATIC DISEASES

Animal models of systemic sclerosis: Prospects and limitations

(2010) Christian Beyer et al.   ARTHRITIS AND RHEUMATISM

Inactivation of the transcription factor STAT-4 prevents inflammation-driven fibrosis in animal models of systemic sclerosis

(2010) Jérôme Avouac et al.   ARTHRITIS AND RHEUMATISM

CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy

(2010) A. Siddiqui-Jain et al.   CANCER RESEARCH

Cellular regulators of protein kinase CK2

(2010) Mathias Montenarh   CELL AND TISSUE RESEARCH

CK2 Modulation of NF- B, TP53, and the Malignant Phenotype in Head and Neck Cancer by Anti-CK2 Oligonucleotides In vitro or In vivo via Sub-50-nm Nanocapsules

(2010) M. S. Brown et al.   CLINICAL CANCER RESEARCH

Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis

(2009) Alfiya Akhmetshina et al.   ARTHRITIS AND RHEUMATISM

The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis

(2009) Nicole Reich et al.   ARTHRITIS AND RHEUMATISM

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts

(2008) Alfiya Akhmetshina et al.   ARTHRITIS AND RHEUMATISM

A structural insight into CK2 inhibition

(2008) Marco Mazzorana et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Too much of a good thing: The role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2

(2007) James S. Duncan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS