BRAFV600E-mutation is invariably present and associated to oncogene-induced senescence in Erdheim-Chester disease

The multifaceted clinical presentations and manifestations of Erdheim–Chester disease: comprehensive review of the literature and of 10 new cases

(2013) Giulio Cavalli et al.   ANNALS OF THE RHEUMATIC DISEASES

Detection of an NRAS mutation in Erdheim-Chester disease

(2013) E. L. Diamond et al.   BLOOD

Pulmonary Langerhans Cell Histiocytosis

(2013) Samuel A. Yousem et al.   CHEST

Which drug, and when, for patients with BRAF-mutant melanoma?

(2013) Sekwon Jang et al.   LANCET ONCOLOGY

T-helper-1-cell cytokines drive cancer into senescence

(2013) Heidi Braumüller et al.   NATURE

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

(2013) Jan R. Dörr et al.   NATURE

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

(2013) Juan Carlos Acosta et al.   NATURE CELL BIOLOGY

Selumetinib-Enhanced Radioiodine Uptake in Advanced Thyroid Cancer

(2013) Alan L. Ho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Erdheim-Chester Disease

(2013) Julien Haroche et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation

(2012) J. Haroche et al.   BLOOD

High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses

(2012) J. Haroche et al.   BLOOD

BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis

(2012) F. Sahm et al.   BLOOD

Immune surveillance of senescent cells--biological significance in cancer- and non-cancer pathologies

(2012) L. Hoenicke et al.   CARCINOGENESIS

Tumor Necrosis Factor α As a Master Regulator of Inflammation in Erdheim-Chester Disease: Rationale for the Treatment of Patients With Infliximab

(2012) Lorenzo Dagna et al.   JOURNAL OF CLINICAL ONCOLOGY

Erdheim-Chester Disease Harboring the BRAF V600E Mutation

(2012) Piers Blombery et al.   JOURNAL OF CLINICAL ONCOLOGY

BRAF Mutations in Erdheim-Chester Disease

(2012) Jean-François Emile et al.   JOURNAL OF CLINICAL ONCOLOGY

Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations

(2012) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma

(2012) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

B-RAF Mutant Alleles Associated with Langerhans Cell Histiocytosis, a Granulomatous Pediatric Disease

(2012) Takeshi Satoh et al.   PLoS One

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody

(2011) David Capper et al.   ACTA NEUROPATHOLOGICA

CNS involvement and treatment with interferon-  are independent prognostic factors in Erdheim-Chester disease: a multicenter survival analysis of 53 patients

(2011) L. Arnaud et al.   BLOOD

Systemic perturbation of cytokine and chemokine networks in Erdheim-Chester disease: a single-center series of 37 patients

(2011) L. Arnaud et al.   BLOOD

Genetic Aberrations Leading to MAPK Pathway Activation Mediate Oncogene-Induced Senescence in Sporadic Pilocytic Astrocytomas

(2011) K. Jacob et al.   CLINICAL CANCER RESEARCH

Erdheim-Chester Disease

(2011) Emanuel Della Torre et al.   CLINICAL NUCLEAR MEDICINE

Erdheim–Chester disease

(2011) Julien Haroche et al.   CURRENT OPINION IN RHEUMATOLOGY

Detection of KRAS and BRAF Mutations in Colorectal Carcinoma

(2011) Maria Arcila et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Up and downregulation of p16Ink4a expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer

(2011) Lydia Kriegl et al.   MODERN PATHOLOGY

BRAFMutations in Hairy-Cell Leukemia

(2011) Enrico Tiacci et al.   NEW ENGLAND JOURNAL OF MEDICINE

BRAF as therapeutic target in melanoma

(2010) Claudia Wellbrock et al.   BIOCHEMICAL PHARMACOLOGY

Rationale and efficacy of interleukin-1 targeting in Erdheim-Chester disease

(2010) A. Aouba et al.   BLOOD

Recurrent BRAF mutations in Langerhans cell histiocytosis

(2010) G. Badalian-Very et al.   BLOOD

Erdheim-Chester disease: report on a case and new insights on its immunopathogenesis

(2010) L. Dagna et al.   RHEUMATOLOGY

Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

(2008) Thomas Kuilman et al.   CELL

Selective Amplification of Rare Mutations Using Locked Nucleic Acid Oligonucleotides that Competitively Inhibit Primer Binding to Wild-Type DNA

(2007) Reid P. Oldenburg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY