Zonulin, regulation of tight junctions, and autoimmune diseases

Haptoglobin Polymorphism as a Risk Factor for Chronic Kidney Disease: A Case-Control Study

(2011) Yi-Chun Chen et al.   AMERICAN JOURNAL OF NEPHROLOGY

Effects of haptoglobin polymorphisms and deficiency on susceptibility to inflammatory bowel disease and on severity of murine colitis

(2011) L Márquez et al.   GUT

Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease

(2011) Michael Schumann et al.   GUT

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

(2011) Alessio Fasano   PHYSIOLOGICAL REVIEWS

Haptoglobin (HP) polymorphisms and human longevity: A cross-sectional association study in a Central Italy population

(2010) Valerio Napolioni et al.   CLINICA CHIMICA ACTA

The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update

(2010) H. Okada et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat

(2010) J. T. J. Visser et al.   DIABETOLOGIA

The active Zot domain (aa 288–293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation

(2010) Simeon E. Goldblum et al.   FASEB JOURNAL

Intestinal barrier gene variants may not explain the increased levels of antigliadin antibodies, suggesting other mechanisms than altered permeability

(2010) Victorien M. Wolters et al.   HUMAN IMMUNOLOGY

Multiple facets of intestinal permeability and epithelial handling of dietary antigens

(2010) S Ménard et al.   Mucosal Immunology

Unlocking the pathogenesis of celiac disease

(2010) Robert M Plenge   NATURE GENETICS

The Type 1 Diabetes - HLA Susceptibility Interactome - Identification of HLA Genotype-Specific Disease Genes for Type 1 Diabetes

(2010) Caroline Brorsson et al.   PLoS One

Estimating the Cost of Type 1 Diabetes in the U.S.: A Propensity Score Matching Method

(2010) Betty Tao et al.   PLoS One

Mucosal expression of claudins 2, 3 and 4 in proximal and distal part of duodenum in children with coeliac disease

(2010) Dorottya Nagy Szakál et al.   VIRCHOWS ARCHIV

An exploration of Glo-3A antibody levels in children at increased risk for type 1 diabetes mellitus

(2009) M Simpson et al.   PEDIATRIC DIABETES

Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2

(2009) A. Tripathi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surprises from Celiac Disease

(2009) Alessio Fasano   SCIENTIFIC AMERICAN

Physiological, Pathological, and Therapeutic Implications of Zonulin-Mediated Intestinal Barrier Modulation

(2008) Alessio Fasano   AMERICAN JOURNAL OF PATHOLOGY

Haptoglobin Polymorphism: A Novel Genetic Risk Factor for Celiac Disease Development and Its Clinical Manifestations

(2008) M. Papp et al.   CLINICAL CHEMISTRY

Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3

(2008) Karen M. Lammers et al.   GASTROENTEROLOGY

Pharmacogenomic application of the haptoglobin genotype in the prevention of diabetic cardiovascular disease

(2008) Shany Blum et al.   PHARMACOGENOMICS

EGF receptor transactivation and MAP kinase mediate proteinase-activated receptor-2-induced chloride secretion in intestinal epithelial cells

(2007) Jacques Q. van der Merwe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY