Hematopoietic stem cells are regulated by Cripto, as an intermediary of HIF-1α in the hypoxic bone marrow niche

Cripto/GRP78 modulation of the TGF-β pathway in development and oncogenesis

(2012) Peter C. Gray et al.   FEBS LETTERS

Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling

(2011) S. Wey et al.   BLOOD

Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

(2011) Satoshi Yamazaki et al.   CELL

Potential for Cripto-1 in defining stem cell-like characteristics in human malignant melanoma

(2011) Luigi Strizzi et al.   CELL CYCLE

Cripto Regulates Hematopoietic Stem Cells as a Hypoxic-Niche-Related Factor through Cell Surface Receptor GRP78

(2011) Kenichi Miharada et al.   Cell Stem Cell

The role of Smad signaling in hematopoiesis and translational hematology

(2011) U Blank et al.   LEUKEMIA

Role of Cripto-1 in Stem Cell Maintenance and Malignant Progression

(2010) Caterina Bianco et al.   AMERICAN JOURNAL OF PATHOLOGY

Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential

(2010) J. Grassinger et al.   BLOOD

Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells

(2010) Y. Nakamura et al.   BLOOD

Distinct Hematopoietic Stem Cell Subtypes Are Differentially Regulated by TGF-β1

(2010) Grant A. Challen et al.   Cell Stem Cell

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

(2010) Tugba Simsek et al.   Cell Stem Cell

Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells

(2010) Keiyo Takubo et al.   Cell Stem Cell

Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

(2010) Yohei Morita et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peptide-binding heat shock protein GRP78 protects cardiomyocytes from hypoxia-induced apoptosis

(2010) Britta Hardy et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Coexistence of Quiescent and Active Adult Stem Cells in Mammals

(2010) L. Li et al.   SCIENCE

Cripto-1 Is a Cell Surface Marker for a Tumorigenic, Undifferentiated Subpopulation in Human Embryonal Carcinoma Cells

(2010) Kazuhide Watanabe et al.   STEM CELLS

Cripto-1 Is Required for Hypoxia to Induce Cardiac Differentiation of Mouse Embryonic Stem Cells

(2009) Caterina Bianco et al.   AMERICAN JOURNAL OF PATHOLOGY

GRP78: A Multifunctional Receptor on the Cell Surface

(2009) Mario Gonzalez–Gronow et al.   ANTIOXIDANTS & REDOX SIGNALING

Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential

(2009) D. G. Kent et al.   BLOOD

Enhancement of Notch receptor maturation and signaling sensitivity by Cripto-1

(2009) Kazuhide Watanabe et al.   JOURNAL OF CELL BIOLOGY

Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways

(2009) J A Kelber et al.   ONCOGENE

A Continuum of Cell States Spans Pluripotency and Lineage Commitment in Human Embryonic Stem Cells

(2009) Shelley R. Hough et al.   PLoS One

Proteomics reveals lowering oxygen alters cytoskeletal and endoplasmatic stress proteins in human endothelial cells

(2009) Louise Østergaard et al.   PROTEOMICS

TGF-  as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation

(2008) S. Yamazaki et al.   BLOOD

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

(2008) Sean J. Morrison et al.   CELL

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

N-Cadherin Expression Level Distinguishes Reserved versus Primed States of Hematopoietic Stem Cells

(2008) Jeffrey S. Haug et al.   Cell Stem Cell

The role of oxygen availability in embryonic development and stem cell function

(2008) M. Celeste Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche

(2007) Yoshiaki Kubota et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS