Macrolide antibiotics in the ribosome exit tunnel: species-specific binding and action

Nascent Peptide in the Ribosome Exit Tunnel Affects Functional Properties of the A-Site of the Peptidyl Transferase Center

(2011) Haripriya Ramu et al.   MOLECULAR CELL

Role of antibiotic ligand in nascent peptide-dependent ribosome stalling

(2011) N. Vazquez-Laslop et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Picky nascent peptides do not talk to foreign ribosomes

(2011) N. Vazquez-Laslop et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding and Action of CEM-101, a New Fluoroketolide Antibiotic That Inhibits Protein Synthesis

(2010) B. Llano-Sotelo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Interplay between the Ribosomal Tunnel, Nascent Chain, and Macrolides Influences Drug Inhibition

(2010) Agata L. Starosta et al.   CHEMISTRY & BIOLOGY

Structural signatures of antibiotic binding sites on the ribosome

(2010) Hilda David-Eden et al.   NUCLEIC ACIDS RESEARCH

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

(2010) J. A. Dunkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting the structures of several antibiotics bound to the bacterial ribosome

(2010) D. Bulkley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortui

(2009) G. Gurel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

CEM-101, a novel fluoroketolide: antimicrobial activity against a diverse collection of Gram-positive and Gram-negative bacteria

(2009) Shannon D. Putnam et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Erythromycin resistance by L4/L22 mutations and resistance masking by drug efflux pump deficiency

(2009) Martin Lovmar et al.   EMBO JOURNAL

Erythromycin- and Chloramphenicol-Induced Ribosomal Assembly Defects Are Secondary Effects of Protein Synthesis Inhibition

(2008) T. Siibak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An Indigenous Posttranscriptional Modification in the Ribosomal Peptidyl Transferase Center Confers Resistance to an Array of Protein Synthesis Inhibitors

(2008) Seok-Ming Toh et al.   JOURNAL OF MOLECULAR BIOLOGY

Time-Resolved Binding of Azithromycin to Escherichia coli Ribosomes

(2008) Alexandros D. Petropoulos et al.   JOURNAL OF MOLECULAR BIOLOGY

Revisiting the mechanism of macrolide-antibiotic resistance mediated by ribosomal protein L22

(2008) S. D. Moore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA