The establishment of early B cell tolerance in humans: lessons from primary immunodeficiency diseases

The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

(2011) Laurence Menard et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation-induced cytidine deaminase mediates central tolerance in B cells

(2011) M. Kuraoka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans

(2011) G. Meyers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Origins of Anti-DNA Antibodies and Their Implications for B-Cell Tolerancea

(2010) MARKO Z. RADIC et al.   Annals of the New York Academy of Sciences

Inflammation-independent defective early B cell tolerance checkpoints in rheumatoid arthritis

(2010) Laurence Menard et al.   ARTHRITIS AND RHEUMATISM

Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

(2010) I. Isnardi et al.   BLOOD

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

(2010) Bing He et al.   NATURE IMMUNOLOGY

AID constrains germinal center size by rendering B cells susceptible to apoptosis

(2009) A. Zaheen et al.   BLOOD

Activation-Induced Cytidine Deaminase Expression and Activity in the Absence of Germinal Centers: Insights into Hyper-IgM Syndrome

(2009) M. Kuraoka et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: The PTPN22 Allelic Variant Associated with Autoimmunity Impairs B Cell Signaling

(2009) A. F. Arechiga et al.   JOURNAL OF IMMUNOLOGY

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

B-cell tolerance checkpoints in health and autoimmunity

(2008) Eric Meffre et al.   CURRENT OPINION IN IMMUNOLOGY

IRAK-4- and MyD88-Dependent Pathways Are Essential for the Removal of Developing Autoreactive B Cells in Humans

(2008) Isabelle Isnardi et al.   IMMUNITY

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

(2008) You-Me Kim et al.   NATURE

B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis

(2008) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

(2007) Thomas Tiller et al.   JOURNAL OF IMMUNOLOGICAL METHODS