Hypomyelinating leukodystrophies: Translational research progress and prospects

Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

(2014) Nicolas Snaidero et al.   CELL

Longitudinal positron emission tomography imaging for monitoring myelin repair in the spinal cord

(2013) Chunying Wu et al.   ANNALS OF NEUROLOGY

Human iPSC-Derived Oligodendrocyte Progenitor Cells Can Myelinate and Rescue a Mouse Model of Congenital Hypomyelination

(2013) Su Wang et al.   Cell Stem Cell

Neurochemistry in shiverer mouse depicted on MR spectroscopy

(2013) Jun-ichi Takanashi et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Synthesis and Characterization of a Novel Gadolinium-Based Contrast Agent for Magnetic Resonance Imaging of Myelination

(2013) Luca Frullano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Myelin water mapping by spatially regularized longitudinal relaxographic imaging at high magnetic fields

(2013) Christian Labadie et al.   MAGNETIC RESONANCE IN MEDICINE

Generation of oligodendroglial cells by direct lineage conversion

(2013) Nan Yang et al.   NATURE BIOTECHNOLOGY

Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

(2013) Fadi J Najm et al.   NATURE BIOTECHNOLOGY

A rapid and reproducible assay for modeling myelination by oligodendrocytes using engineered nanofibers

(2013) Seonok Lee et al.   Nature Protocols

PET imaging of demyelination and remyelination in the cuprizone mouse model for multiple sclerosis: A comparison between [11C]CIC and [11C]MeDAS

(2013) Daniele de Paula Faria et al.   NEUROIMAGE

Evolving Concepts of Gliogenesis: A Look Way Back and Ahead to the Next 25 Years

(2013) Marc R. Freeman et al.   NEURON

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Oligodendroglia: metabolic supporters of axons

(2013) Brett M. Morrison et al.   TRENDS IN CELL BIOLOGY

Assessment of myelination in hypomyelinating disorders by quantitative MRI

(2012) Steffi F. Dreha-Kulaczewski et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

The Energetics of CNS White Matter

(2012) J. J. Harris et al.   JOURNAL OF NEUROSCIENCE

On the inherent precision of mcDESPOT

(2012) Christopher L. Lankford et al.   MAGNETIC RESONANCE IN MEDICINE

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Quantitative MR imaging of two-pool magnetization transfer model parameters in myelin mutant shaking pup

(2012) Alexey Samsonov et al.   NEUROIMAGE

Rapid whole cerebrum myelin water imaging using a 3D GRASE sequence

(2012) Thomas Prasloski et al.   NEUROIMAGE

Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time mapping

(2012) Sean C.L. Deoni et al.   NEUROIMAGE

Direct magnetic resonance detection of myelin and prospects for quantitative imaging of myelin density

(2012) M. J. Wilhelm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glial Progenitor Cell-Based Treatment and Modeling of Neurological Disease

(2012) S. A. Goldman et al.   SCIENCE

Human Neural Stem Cells Induce Functional Myelination in Mice with Severe Dysmyelination

(2012) N. Uchida et al.   Science Translational Medicine

Neural Stem Cell Engraftment and Myelination in the Human Brain

(2012) N. Gupta et al.   Science Translational Medicine

Biogenesis and Significance of Central Nervous System Myelin

(2012) M. Soldán et al.   SEMINARS IN NEUROLOGY

Mutations of POLR3A Encoding a Catalytic Subunit of RNA Polymerase Pol III Cause a Recessive Hypomyelinating Leukodystrophy

(2011) Geneviève Bernard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Recessive Mutations in POLR3B, Encoding the Second Largest Subunit of Pol III, Cause a Rare Hypomyelinating Leukodystrophy

(2011) Martine Tétreault et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Neurodegenerative Disorder Related to AIMP1/p43 Mutation Is Not a PMLD

(2011) Odile Boespflug-Tanguy et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Myelin Regeneration: A Recapitulation of Development?

(2011) Stephen P.J. Fancy et al.   Annual Review of Neuroscience

Increased N-acetylaspartate in model mouse of pelizaeus-merzbacher disease

(2011) Jun-ichi Takanashi et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Is the magnetization transfer ratio a marker for myelin in multiple sclerosis?

(2011) Irene M. Vavasour et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Regulation of Oligodendrocyte Development and Myelination by Glucose and Lactate

(2011) J. E. Rinholm et al.   JOURNAL OF NEUROSCIENCE

Misalignment of PLP/DM20 Transmembrane Domains Determines Protein Misfolding in Pelizaeus-Merzbacher Disease

(2011) A. S. Dhaunchak et al.   JOURNAL OF NEUROSCIENCE

Genetic engineering of human pluripotent cells using TALE nucleases

(2011) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

High b-value and diffusion tensor imaging in a canine model of dysmyelination and brain maturation

(2011) Yu-Chien Wu et al.   NEUROIMAGE

Deficient MWF mapping in multiple sclerosis using 3D whole-brain multi-component relaxation MRI

(2011) Hagen H. Kitzler et al.   NEUROIMAGE

Myelin water imaging reflects clinical variability in multiple sclerosis

(2011) Shannon Kolind et al.   NEUROIMAGE

High-resolution diffusion tensor imaging of fixed brain in a mouse model of Pelizaeus-Merzbacher disease: comparison with quantitative measures of white matter pathology

(2011) Torsten Ruest et al.   NMR IN BIOMEDICINE

Induced pluripotent stem cells: opportunities and challenges

(2011) K. Okita et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Pelizaeus-Merzbacher-like Disease Caused by AIMP1/p43 Homozygous Mutation

(2010) Miora Feinstein et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Magnetic resonance imaging of a unique mutation in a family with Pelizaeus-Merzbacher disease

(2010) Elka Miller et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A novel PET marker for in vivo quantification of myelination

(2010) Chunying Wu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Magnetic resonance imaging pattern recognition in hypomyelinating disorders

(2010) Marjan E. Steenweg et al.   BRAIN

Pathological basis of diffusely abnormal white matter: insights from magnetic resonance imaging and histology

(2010) Cornelia Laule et al.   Multiple Sclerosis Journal

Tremor–ataxia with central hypomyelination (TACH) leukodystrophy maps to chromosome 10q22.3–10q23.31

(2010) Geneviève Bernard et al.   NEUROGENETICS

Fast bound pool fraction imaging of the in vivo rat brain: Association with myelin content and validation in the C6 glioma model

(2010) Hunter R. Underhill et al.   NEUROIMAGE

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

On the biogenesis of myelin membranes: Sorting, trafficking and cell polarity

(2009) Wia Baron et al.   FEBS LETTERS

Characterizing healthy and diseased white matter using quantitative magnetization transfer and multicomponentT2relaxometry: A unified view via a four-pool model

(2009) Ives R. Levesque et al.   MAGNETIC RESONANCE IN MEDICINE

Quantitative magnetization transfer measured pool-size ratio reflects optic nerve myelin content in ex vivo mice

(2009) Xiawei Ou et al.   MAGNETIC RESONANCE IN MEDICINE

Differentiation of human oligodendrocytes from pluripotent stem cells

(2009) Bao-Yang Hu et al.   Nature Protocols

Invited Article: An MRI-based approach to the diagnosis of white matter disorders

(2009) R. Schiffmann et al.   NEUROLOGY

AGC1 Deficiency and Cerebral Hypomyelination

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

AGC1 Deficiency Associated with Global Cerebral Hypomyelination

(2009) Rolf Wibom et al.   NEW ENGLAND JOURNAL OF MEDICINE

The MT pool size ratio and the DTI radial diffusivity may reflect the myelination in shiverer and control mice

(2009) Xiawei Ou et al.   NMR IN BIOMEDICINE

Mitochondrial Hsp60 Chaperonopathy Causes an Autosomal-Recessive Neurodegenerative Disorder Linked to Brain Hypomyelination and Leukodystrophy

(2008) Daniella Magen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Is diffusion anisotropy an accurate monitor of myelination?

(2008) Burkhard Mädler et al.   MAGNETIC RESONANCE IMAGING

Gleaning multicomponentT1andT2information from steady-state imaging data

(2008) Sean C.L. Deoni et al.   MAGNETIC RESONANCE IN MEDICINE

Stem cell therapy in multiple sclerosis: promise and controversy

(2008) ID Duncan et al.   Multiple Sclerosis Journal

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE