Multiscale Systems Biology and Physics of Thrombosis Under Flow

Blood Clot Formation under Flow: The Importance of Factor XI Depends Strongly on Platelet Count

(2012) Aaron L. Fogelson et al.   BIOPHYSICAL JOURNAL

Multiscale prediction of patient-specific platelet function under flow

(2012) M. H. Flamm et al.   BLOOD

Dissociation of Bimolecular αIIbβ3-Fibrinogen Complex under a Constant Tensile Force

(2011) Rustem I. Litvinov et al.   BIOPHYSICAL JOURNAL

Polymer-Based Catch-Bonds

(2011) Hsieh Chen et al.   BIOPHYSICAL JOURNAL

Multivalent Binding of Nanocarrier to Endothelial Cells under Shear Flow

(2011) Jin Liu et al.   BIOPHYSICAL JOURNAL

Dilutional Control of Prothrombin Activation at Physiologically Relevant Shear Rates

(2011) Laura M. Haynes et al.   BIOPHYSICAL JOURNAL

PlateletWeb: a systems biologic analysis of signaling networks in human platelets

(2011) D. Boyanova et al.   BLOOD

Membrane Binding Events in the Initiation and Propagation Phases of Tissue Factor-initiated Zymogen Activation under Flow

(2011) Laura M. Haynes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Simulation of aggregating particles in complex flows by the lattice kinetic Monte Carlo method

(2011) Matthew H. Flamm et al.   JOURNAL OF CHEMICAL PHYSICS

Mathematical model of PAR1-mediated activation of human platelets

(2011) Leonardo Lenoci et al.   Molecular BioSystems

Shear-induced platelet margination in a microchannel

(2011) Hong Zhao et al.   PHYSICAL REVIEW E

Predicting human blood viscosity in silico

(2011) D. A. Fedosov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Morphology of Platelet Aggregates Formed on Collagen Under Laminar Blood Flow

(2010) T. Colace et al.   ANNALS OF BIOMEDICAL ENGINEERING

Signaling During Platelet Adhesion and Activation

(2010) Zhenyu Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Multiscale Red Blood Cell Model with Accurate Mechanics, Rheology, and Dynamics

(2010) Dmitry A. Fedosov et al.   BIOPHYSICAL JOURNAL

A Multiscale Model of Venous Thrombus Formation with Surface-Mediated Control of Blood Coagulation Cascade

(2010) Zhiliang Xu et al.   BIOPHYSICAL JOURNAL

P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions

(2010) S. F. Maloney et al.   Integrative Biology

Grow with the flow: a spatial-temporal model of platelet deposition and blood coagulation under flow

(2010) K. Leiderman et al.   MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA

A mechanically stabilized receptor–ligand flex-bond important in the vasculature

(2010) Jongseong Kim et al.   NATURE

Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuli

(2010) Manash S Chatterjee et al.   NATURE BIOTECHNOLOGY

Systems Biology of Coagulation Initiation: Kinetics of Thrombin Generation in Resting and Activated Human Blood

(2010) Manash S. Chatterjee et al.   PLoS Computational Biology

Computational model of whole blood exhibiting lateral platelet motion induced by red blood cells

(2009) Lindsay M. Crowl et al.   International Journal for Numerical Methods in Biomedical Engineering

Lattice kinetic Monte Carlo simulations of convective-diffusive systems

(2009) Matthew H. Flamm et al.   JOURNAL OF CHEMICAL PHYSICS

A shear gradient–dependent platelet aggregation mechanism drives thrombus formation

(2009) Warwick S Nesbitt et al.   NATURE MEDICINE

Three-dimensional computational modeling of multiple deformable cells flowing in microvessels

(2009) Sai K. Doddi et al.   PHYSICAL REVIEW E

An extended convection diffusion model for red blood cell-enhanced transport of thrombocytes and leukocytes

(2009) S J Hund et al.   PHYSICS IN MEDICINE AND BIOLOGY

Steady-State Kinetic Modeling Constrains Cellular Resting States and Dynamic Behavior

(2009) Jeremy E. Purvis et al.   PLoS Computational Biology

Blood Flow in End-to-Side Anastomoses

(2008) Francis Loth et al.   Annual Review of Fluid Mechanics

Relaxation of ultralarge VWF bundles in a microfluidic–AFM hybrid reactor

(2008) D.M. Steppich et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Platelet Adhesive Dynamics. Part I: Characterization of Platelet Hydrodynamic Collisions and Wall Effects

(2008) Nipa A. Mody et al.   BIOPHYSICAL JOURNAL

A molecular signaling model of platelet phosphoinositide and calcium regulation during homeostasis and P2Y1 activation

(2008) J. E. Purvis et al.   BLOOD

Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow

(2008) U. M. Okorie et al.   BLOOD

Study of blood flow impact on growth of thrombi using a multiscale model

(2008) Zhiliang Xu et al.   Soft Matter

Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress

(2007) K. Shim et al.   BLOOD

A multiscale model of thrombus development

(2007) Z. Xu et al.   Journal of the Royal Society Interface