Intracellular Trafficking Considerations in the Development of Natural Ligand-Drug Molecular Conjugates for Cancer

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Intratumoral Therapy of Glioblastoma Multiforme Using Genetically Engineered Transferrin for Drug Delivery

(2010) Dennis J. Yoon et al.   CANCER RESEARCH

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

(2010) Mark T. Howes et al.   JOURNAL OF CELL BIOLOGY

Folate-Targeted Therapies for Cancer

(2010) Wei Xia et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma

(2010) S. Kunwar et al.   NEURO-ONCOLOGY

Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics

(2010) M. Candolfi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Folate-targeted therapeutic and imaging agents for cancer

(2009) Philip Stewart Low et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

IL-13 receptor-α2: a novel target for cancer therapy

(2009) Bharat H Joshi et al.   Immunotherapy

In Vivo Structural Activity and Optimization Studies of Folate−Tubulysin Conjugates

(2009) Joseph A. Reddy et al.   MOLECULAR PHARMACEUTICS

Folate Targeting Enables Durable and Specific Antitumor Responses from a Therapeutically Null Tubulysin B Analogue

(2008) C. P. Leamon et al.   CANCER RESEARCH

Genetically designing a more potent antipancreatic cancer agent by simultaneously co-targeting human IL13 and EGF receptors in a mouse xenograft model

(2008) D. A. Vallera et al.   GUT

IL-13 cytotoxin has potent antitumor activity and synergizes with paclitaxel in a mouse model of oral squamous cell carcinoma

(2008) Mitomu Kioi et al.   INTERNATIONAL JOURNAL OF CANCER

A Role for the Proton-coupled Folate Transporter (PCFT-SLC46A1) in Folate Receptor-mediated Endocytosis

(2008) Rongbao Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The epidermal growth factor receptor ligands at a glance

(2008) Marlon R. Schneider et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Genetically engineering transferrin to improve its in vitro ability to deliver cytotoxins

(2008) Dennis J. Yoon et al.   JOURNAL OF CONTROLLED RELEASE

Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors

(2008) John H. Sampson et al.   NEURO-ONCOLOGY

Improving Therapeutic Properties of Protein Drugs through Alteration of Intracellular Trafficking Pathways

(2007) B.J. Lao et al.   BIOTECHNOLOGY PROGRESS