Constrained Peptides with Target-Adapted Cross-Links as Inhibitors of a Pathogenic Protein-Protein Interaction

Inhibition of α-helix-mediated protein–protein interactions using designed molecules

(2013) Valeria Azzarito et al.   Nature Chemistry

Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy

(2013) Yong S. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bicyclic Peptide Inhibitor Reveals Large Contact Interface with a Protease Target

(2012) Alessandro Angelini et al.   ACS Chemical Biology

Small-Molecule Stabilization of Protein-Protein Interactions: An Underestimated Concept in Drug Discovery?

(2012) Philipp Thiel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multivalent glycoconjugates as anti-pathogenic agents

(2012) Anna Bernardi et al.   CHEMICAL SOCIETY REVIEWS

Minimalist and universal peptidomimetics

(2011) Eunhwa Ko et al.   CHEMICAL SOCIETY REVIEWS

Structure of the Stapled p53 Peptide Bound to Mdm2

(2011) Sohee Baek et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design and Structure of Stapled Peptides Binding to Estrogen Receptors

(2011) Chris Phillips et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Contemporary strategies for peptide macrocyclization

(2011) Christopher J. White et al.   Nature Chemistry

Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis

(2011) Young-Woo Kim et al.   Nature Protocols

Electrostatic interactions play a minor role in the binding of ExoS to 14-3-3 proteins

(2010) Lubna Yasmin et al.   BIOCHEMICAL JOURNAL

The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer

(2010) Michelle L Stewart et al.   Nature Chemical Biology

Solid-phase synthesis of short α-helices stabilized by the hydrogen bond surrogate approach

(2010) Anupam Patgiri et al.   Nature Protocols

Can self-inhibitory peptides be derived from the interfaces of globular protein-protein interactions?

(2010) Nir London et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

(2010) N. Srinivas et al.   SCIENCE

Inhibition of protein–protein interactions using designed molecules

(2009) Andrew J. Wilson   CHEMICAL SOCIETY REVIEWS

β-Hairpin Peptidomimetics: Design, Structures and Biological Activities

(2008) John A. Robinson   ACCOUNTS OF CHEMICAL RESEARCH