Total Synthesis of the Tiacumicin B (Lipiarmycin A3/Fidaxomicin) Aglycone

Application of Cross Metathesis in Diene and Polyene Synthesis

(2013) Agnieszka Wojtkielewicz   CURRENT ORGANIC SYNTHESIS

Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA

(2013) Ruben C Hartkoorn et al.   Nature Chemical Biology

Total Synthesis of the Bacterial RNA Polymerase Inhibitor Ripostatin B

(2012) Florian Glaus et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereodivergent Synthesis of Trisubstituted Alkenes through Protodeboronation of Allylic Boronic Esters: Application to the Synthesis of the Californian Red Scale Beetle Pheromone

(2012) Matthew J. Hesse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antimicrobial Activities of Fidaxomicin

(2012) Ellie J. C. Goldstein et al.   CLINICAL INFECTIOUS DISEASES

Fidaxomicin Is an Inhibitor of the Initiation of Bacterial RNA Synthesis

(2012) Irina Artsimovitch et al.   CLINICAL INFECTIOUS DISEASES

Fidaxomicin Attains High Fecal Concentrations With Minimal Plasma Concentrations Following Oral Administration in Patients With Clostridium difficile Infection

(2012) P. Sears et al.   CLINICAL INFECTIOUS DISEASES

Regiocontrolled CuI-Catalyzed Borylation of Propargylic-Functionalized Internal Alkynes

(2012) Abraham L. Moure et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From natural product to marketed drug: the tiacumicin odyssey

(2012) William Erb et al.   NATURAL PRODUCT REPORTS

Synthesis and Antimycobacterial Activity of 2,1′-Dihydropyridomycins

(2012) Oliver P. Horlacher et al.   ACS Medicinal Chemistry Letters

Characterization of a Sugar-O-methyltransferase TiaS5 Affords New Tiacumicin Analogues with Improved Antibacterial Properties and Reveals Substrate Promiscuity

(2011) Siwen Niu et al.   CHEMBIOCHEM

A More Comprehensive and Highly Practical Solution to Enantioselective Aldehyde Crotylation

(2011) Hyunwoo Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of Tiacumicin B Biosynthetic Gene Cluster Affording Diversified Tiacumicin Analogues and Revealing a Tailoring Dihalogenase

(2010) Yi Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

European Society of Clinical Microbiology and Infectious Diseases (ESCMID): Data review and recommendations for diagnosing Clostridium difficile-infection (CDI)

(2009) M.J.T. Crobach et al.   CLINICAL MICROBIOLOGY AND INFECTION

Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis

(2008) M. Kurabachew et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY