Editorial Material
Chemistry, Multidisciplinary
Pavel A. Dub
Summary: In this study, the structure and reactivity of a long-postulated intermediate - the alkali metal amidate complex - in homogeneous hydrogenation reactions using Noyori-type catalysts and inorganic bases were reported through experimental and computational studies.
Article
Chemistry, Multidisciplinary
Gabriele Hierlmeier, Paolo Tosatti, Kurt Puentener, Paul J. J. Chirik
Summary: This study reports a new molybdenum ligand for catalyzing the hydrogenation of benzene, which is formed by the coordination of phosphino(imino)pyridine and cyclooctadiene. The experimental results indicate that the ligand can selectively generate cyclohexane catalyst in the presence of benzene, and the formation of the insertion product is a key step.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Na Li, Liang Cai, Guoping Gao, Yue Lin, Chao Wang, Hengjie Liu, Yuying Liu, Hengli Duan, Qianqian Ji, Wei Hu, Hao Tan, Zeming Qi, Lin-Wang Wang, Wensheng Yan
Summary: We report record stability and high iridium mass activity of Ca2-xIrO4 nanocrystals, with 300 h continuous operation and an activity about 62 times higher than benchmark IrO2. The Ir-rich surface layer, evolved from one-dimensional connected edge-sharing [IrO6] octahedrons, is responsible for the high activity and long-term stability. We also observe key intermediates on iridium-based oxides electrocatalysts and find that they are stable even at low voltages. Density functional theory calculations suggest that the catalytic activity of Ca2IrO4 is enhanced remarkably after surface Ca leaching, allowing for stabilization of IrOO- and Ir=O intermediates on positive charged active sites of the Ir-rich surface layer.
Article
Chemistry, Multidisciplinary
Wei Zhao, Wenji Wang, Huan Zhou, Qishan Liu, Zhiqing Ma, Haizhou Huang, Mingxin Chang
Summary: A one-pot asymmetric hydrogenation of pyridines with subsequent N-alkylation using a traceless Bronsted acid activation strategy is reported. The reaction exhibits high stereoselectivity and can be used to synthesize indolizidines and quinolizidines. Experimental and theoretical studies reveal that chloride anion and noncovalent interactions play important roles in determining the stereoselectivity of the reaction.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Chemistry, Multidisciplinary
Anja Loncar, Daniel Escalera-Lopez, Serhiy Cherevko, Nejc Hodnik
Summary: This Minireview gathers the state-of-the-art understanding of the dissolution of different iridium catalysts and its relationship with their structure, and correlates it to the different mechanisms of the oxygen evolution reaction (OER). It is of great importance for the scale-up of green hydrogen production.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Jun Hu, Ting Wang, Wen-Jun Zhang, Han Hao, Qiao Yu, Hang Gao, Nan Zhang, Yun Chen, Xing-Hua Xia, Hong-Yuan Chen, Jing-Juan Xu
Summary: A novel mass spectrometric method was developed to probe the flash chemistry of electrogenerated reactive intermediates through rapid collision mixing of electrosprayed microdroplets. This method allows for fast identification and exploration of ultrafast initial transformations in the reaction process.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Qian Xu, Thomas R. Hoye
Summary: This study reports the generation of a relatively rare reactive intermediate called alpha,3-dehydrotoluenes from isolable allenynes. The substructure motif in the allenyne substrates is distinct and complementary to other types of cycloisomerizations. The product profiles obtained under different reaction conditions provide insights into the electronic nature of the produced isomeric DHTs and reveal previously unobserved carbene-like reactivity of the DHT.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Monika Kot, Robert Wojcieszak, Ewa Janiszewska, Mariusz Pietrowski, Michal Zielinski
Summary: Commercial silica modified with NH4F or NH4Cl salts and thermally treated can generate acidic sites and alter structural properties, along with additional porosity. NH4F solution leads to decreased specific surface area, increased pore diameter, and higher total acidity. The resulting acid sites' number and strength depend on the anion in the ammonium salt and concentration of the solution. The NH4F-modified silica supported iridium catalyst exhibits higher activity in toluene hydrogenation due to the generation of adsorption centers for toluene.
Article
Chemistry, Multidisciplinary
Frederic C. Meunier, Isaac Dansette, Anaelle Paredes-Nunez, Yves Schuurman
Summary: Cu/ZrO2 is a promising catalyst for CO2 hydrogenation to methanol. Three different types of formates were observed under reaction conditions, with one bound to metallic Cu and the other two bound to ZrO2. The Cu-bound formate, representing only about 7% of surface formates, was found to be highly reactive and the sole source of methanol production. This study highlights the importance of quantitative IR analysis and transient methods in understanding the role of surface species.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Engineering, Environmental
Qicheng Zhang, Yue Song, Bin Chen, Xuewen Hu, Wenchao Peng, Yang Li, Fengbao Zhang, Xiaobin Fan
Summary: Hierarchical nanostructures of MoS2 were obtained through the introduction of saturated NaCl solution during hydrothermal synthesis, leading to significant improvements in the catalytic conversion of p-chloronitrobenzene. The intercalation of Na in MoS2 was found to downshift the d-band center of Mo, favoring the final desorption process.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Nanoscience & Nanotechnology
Hao Yang, Fabio Ribeiro Negreiros, Qintao Sun, Miao Xie, Luca Sementa, Mauro Stener, Yifan Ye, Alessandro Fortunelli, William A. Goddard, Tao Cheng
Summary: This study provides a method to validate the reactive intermediates in the CO2 electroreduction reaction by predicting the core-level shifts and carefully considering solvation effects and applied voltage. The results could guide future experiments to verify and interpret the reaction mechanism of CO2RR.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Physical
Aiping Jia, Hantao Peng, Yunshang Zhang, Tongyang Song, Yanwen Ye, Mengfei Luo, Jiqing Lu, Weixin Huang
Summary: In this study, various supported Ir/TiO2 catalysts were prepared using different Ir precursors and tested for vapor phase selective hydrogenation of crotonaldehyde. The choice of Ir precursor significantly altered the interaction between Ir and TiOx in the catalyst, thus affecting the catalyst's performance.
Article
Chemistry, Physical
Yungen Liu, Ka-Pan Shing, Vanessa Kar-Yan Lo, Chi-Ming Che
Summary: Transition-metal-catalyzed direct C-N bond formation reactions have been widely used for the synthesis of nitrogen-containing compounds. Iron catalysts are promising due to their cost-effectiveness and environmental sustainability, while ruthenium complexes provide more stability for studying the reaction mechanism. This Perspective summarizes the recent developments in iron and ruthenium complexes supported by macrocyclic or polydentate ligands for catalytic amination reactions involving metal imido/nitrene intermediates, and discusses the current limitations and potential opportunities for future research.
Article
Chemistry, Applied
Luis J. Benitez-Puebla, Marcos Flores-Alamo, Katarzyna Wrobel, Kazimierz Wrobel, Oracio Serrano, Miguel A. Vazquez
Summary: A new type of non-symmetrical trans-dichloro-Ir(III) complexes derived from NacNac-type ligands was unexpectedly obtained and characterized. The complexes exhibited high stability in solution and solid state, and their structures were confirmed by NMR, HRMS, and X-ray diffraction. Furthermore, the catalytic activity of these complexes in transfer hydrogenation reactions of ketones and imines was evaluated.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Takumi Koshikawa, Yuki Nagashima, Ken Tanaka
Summary: The study showed that a cationic gold(I)/PCy3 complex catalyzes the intramolecular cascade reaction of enediyne-carbonyls, yielding pentacyclic compounds. The cascade reaction involves [3 + 2] annulation, carbenoid transfer, and C-H insertion in one-pot.
Article
Chemistry, Multidisciplinary
Sean Preshlock, Samuel Calderwood, Stefan Verhoog, Matthew Tredwell, Mickael Huiban, Antje Hienzsch, Stefan Gruber, Thomas C. Wilson, Nicholas J. Taylor, Thomas Cailly, Michael Schedler, Thomas Lee Collier, Jan Passchier, Rene Smits, Jan Mollitor, Alexander Hoepping, Marco Mueller, Christophe Genicot, Joel Mercier, Veronique Gouverneur
CHEMICAL COMMUNICATIONS
(2016)
Article
Chemistry, Inorganic & Nuclear
Stefan Gruber
Article
Chemistry, Multidisciplinary
Stefan Gruber, Simon M. Ametamey, Roger Schibli
CHEMICAL COMMUNICATIONS
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ahmed Haider, Irina Iten, Hazem Ahmed, Adrienne Mueller Herde, Stefan Gruber, Stefanie D. Kraemer, Claudia Keller, Roger Schibli, Bernhard Wuensch, Linjing Mu, Simon M. Ametamey
JOURNAL OF NUCLEAR MEDICINE
(2019)
Article
Chemistry, Applied
Marc-Andre Muller, Stefan Gruber, Andreas Pfaltz
ADVANCED SYNTHESIS & CATALYSIS
(2018)
Article
Chemistry, Multidisciplinary
Matthew Tredwell, Sean M. Preshlock, Nicholas J. Taylor, Stefan Gruber, Mickael Huiban, Jan Passchier, Joel Mercier, Christophe Genicot, Veronique Gouverneur
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2014)
Article
Chemistry, Inorganic & Nuclear
Stefan Gruber, Markus Neuburger, Andreas Pfaltz
Article
Chemistry, Medicinal
Hazem Ahmed, Ahmed Haider, Jasmine Varisco, Maja Stankovic, Rahel Wallimann, Stefan Gruber, Irina Iten, Surya Hane, Adrienne Mueller Herde, Claudia Keller, Roger Schibli, Dirk Schepmann, Linjing Mu, Bernhard Wuensch, Simon M. Ametamey
JOURNAL OF MEDICINAL CHEMISTRY
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hazem Ahmed, Rahel Wallimann, Ahmed Haider, Vahid Hosseini, Stefan Gruber, Marvin Robledo, Thi A. N. Nguyen, Adrienne Muller Herde, Irina Iten, Claudia Keller, Viola Vogel, Roger Schibli, Bernhard Wuensch, Linjing Mu, Simon M. Ametamey
Summary: The study successfully developed a highly efficient PET probe, F-18-OF-NB1, for imaging the GluN2B subunits of the N-methyl-D-aspartate receptor. The probe has the potential for application in PET imaging studies in ALS patients and other brain disorders.
JOURNAL OF NUCLEAR MEDICINE
(2021)
Article
Chemistry, Multidisciplinary
Linjing Mu, Stefanie D. Kramer, Hazem Ahmed, Stefan Gruber, Susanne Geistlich, Roger Schibli, Simon M. Ametamey
Article
Chemistry, Organic
Stefan Gruber, Valerie Waser, Zacharias Thiel, Simon M. Ametamey
Summary: A direct synthesis of a fluorine-18-labeled prodrug of AFA233 was achieved by selectively deprotecting tert-butyl protection groups on the quinoxalinedione moiety, without affecting the tert-butyl-S-acyl-2-thioethyl protection groups on the phosphate esters. Additionally, a nonradioactive prodrug reference compound of AFA233 was prepared.
Meeting Abstract
Radiology, Nuclear Medicine & Medical Imaging
H. Ahmed, A. Haider, V. Hosseini, R. Wallimann, I. Iten, M. Robledo, T. A. N. Nguyen, A. Herde, C. Keller, S. Gruber, V. Vogel, R. Schibli, L. Mu, B. Wuensch, S. M. Ametamey
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2020)
Meeting Abstract
Biochemical Research Methods
Ahmed Haider, Hazem Ahmed, Jasmine Varisco, Maja Stankovic, Rahel Wallimann, Stefan Gruber, Irina Iten, Jose Miguel, Claudia Keller, Roger Schibli, Dirk Schepmann, Linjing Mu, Bernhard Wuensch, Simon Ametamey
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
(2019)
Meeting Abstract
Radiology, Nuclear Medicine & Medical Imaging
A. Haider, I. Iten, H. Ahmed, A. Mueller Herde, S. Gruber, S. Kraemer, C. Keller, R. Schibli, B. Wuensch, L. Mu, S. Ametamey
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2018)