Alkene-Tetrazine Ligation for Imaging Cellular DNA

An Azide-Modified Nucleoside for Metabolic Labeling of DNA

(2014) Anne B. Neef et al.   CHEMBIOCHEM

Non-Enzymatic DNA Cleavage Reaction Induced by 5-Ethynyluracil in Methylamine Aqueous Solution and Application to DNA Concatenation

(2014) Shuji Ikeda et al.   PLoS One

Two-Color Glycan Labeling of Live Cells by a Combination of Diels-Alder and Click Chemistry

(2013) Andrea Niederwieser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tracking Viral Genomes in Host Cells at Single-Molecule Resolution

(2013) I-Hsuan Wang et al.   Cell Host & Microbe

Fluorescent Live-Cell Imaging of Metabolically Incorporated Unnatural Cyclopropene-Mannosamine Derivatives

(2013) Christian M. Cole et al.   CHEMBIOCHEM

Aqueous Oxidative Heck Reaction as a Protein-Labeling Strategy

(2013) Maria Eleni Ourailidou et al.   CHEMBIOCHEM

Bioorthogonal chemistry: strategies and recent developments

(2013) Carlo P. Ramil et al.   CHEMICAL COMMUNICATIONS

EdU induces DNA damage response and cell death in mESC in culture

(2013) Fanni Kohlmeier et al.   CHROMOSOME RESEARCH

DNA damage signaling, impairment of cell cycle progression, and apoptosis triggered by 5-ethynyl-2′-deoxyuridine incorporated into DNA

(2013) Hong Zhao et al.   CYTOMETRY PART A

Adult somatic stem cells in the human parasite Schistosoma mansoni

(2013) James J. Collins III et al.   NATURE

A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-Free Click Reaction

(2012) Emine Kaya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amino Acids for Diels-Alder Reactions in Living Cells

(2012) Tilman Plass et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Specific One-Pot Dual Labeling of DNA by Orthogonal Cycloaddition Chemistry

(2012) Juliane Schoch et al.   BIOCONJUGATE CHEMISTRY

Metabolic Labeling of DNA by Purine Analogues in Vivo

(2012) Anne B. Neef et al.   CHEMBIOCHEM

Strain-Promoted Azide–Alkyne Cycloadditions of Benzocyclononynes

(2012) Jumreang Tummatorn et al.   JOURNAL OF ORGANIC CHEMISTRY

Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions

(2012) Kathrin Lang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functionalized Cyclopropenes As Bioorthogonal Chemical Reporters

(2012) David M. Patterson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

(2012) Kathrin Lang et al.   Nature Chemistry

Most Anti-BrdU Antibodies React with 2′-Deoxy-5-Ethynyluridine — The Method for the Effective Suppression of This Cross-Reactivity

(2012) Radek Liboska et al.   PLoS One

Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaks

(2012) Xiao-Jun Liu et al.   Chinese Journal of Cancer

Bioconjugation with Strained Alkenes and Alkynes

(2011) Marjoke F. Debets et al.   ACCOUNTS OF CHEMICAL RESEARCH

Photoinducible Bioorthogonal Chemistry: A Spatiotemporally Controllable Tool to Visualize and Perturb Proteins in Live Cells

(2011) Reyna K. V. Lim et al.   ACCOUNTS OF CHEMICAL RESEARCH

5-Ethynyl-2′-deoxycytidine as a new agent for DNA labeling: Detection of proliferating cells

(2011) Dezhong Qu et al.   ANALYTICAL BIOCHEMISTRY

Intracellular Detection of Cytosine Incorporation in Genomic DNA by Using 5-Ethynyl-2′-Deoxycytidine

(2011) Lirui Guan et al.   CHEMBIOCHEM

Strain-Promoted Alkyne-Azide Cycloadditions (SPAAC) Reveal New Features of Glycoconjugate Biosynthesis

(2011) Ngalle Eric Mbua et al.   CHEMBIOCHEM

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosides

(2011) A. B. Neef et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonogenic Neoblasts Are Pluripotent Adult Stem Cells That Underlie Planarian Regeneration

(2011) D. E. Wagner et al.   SCIENCE

Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three-Dimensional Imaging of Living Cells

(2010) Jan Dommerholt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Directed Spin-Labeling of DNA by the Azide-Alkyne ‘Click’ Reaction: Nanometer Distance Measurements on 7-Deaza-2′-deoxyadenosine and 2′-Deoxyuridine Nitroxide Conjugates Spatially Separated or Linked to a ‘dA-dT’ Base Pair

(2010) Ping Ding et al.   CHEMISTRY-A EUROPEAN JOURNAL

Post-Synthetic Modification of DNA by Inverse-Electron-Demand Diels−Alder Reaction

(2010) Juliane Schoch et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organization of DNA Replication

(2010) V. O. Chagin et al.   Cold Spring Harbor Perspectives in Biology

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition

(2009) Neal K. Devaraj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Click Chemistry and Bioorthogonal Reactions: Unprecedented Selectivity in the Labeling of Biological Molecules

(2009) Michael D. Best   BIOCHEMISTRY

Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloadditions

(2008) Xinghai Ning et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

(2008) Neal K. Devaraj et al.   BIOCONJUGATE CHEMISTRY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A chemical method for fast and sensitive detection of DNA synthesis in vivo

(2008) A. Salic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA