Rapid Access to β-Trifluoromethyl-Substituted Ketones: Harnessing Inductive Effects in Wacker-Type Oxidations of Internal Alkenes

Catalyst-Controlled Wacker-Type Oxidation: Facile Access to Functionalized Aldehydes

(2014) Zachary K. Wickens et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A density functional study of chiral phosphoric acid-catalyzed direct arylation of trifluoromethyl ketone and diarylation of methyl ketone: reaction mechanism and the important role of the CF3 group

(2014) Aiping Fu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium-Catalyzed Selective Anti-Markovnikov Oxidation of Allylic Esters

(2013) Jia Jia Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Practical and General Palladium-Catalyzed Synthesis of Ketones from Internal Olefins

(2013) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective Wacker Oxidation of Internal Alkenes: Rapid Access to Functionalized Ketones Facilitated by Cross-Metathesis

(2013) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aldehyde-Selective Wacker-Type Oxidation of Unbiased Alkenes Enabled by a Nitrite Co-Catalyst

(2013) Zachary K. Wickens et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Atom-Efficient Oxidation of Electron-Deficient Internal Olefins to Ketones Using a Palladium Catalyst

(2013) Takato Mitsudome et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Wacker-Type Oxidation of Internal Alkenes using Pd(Quinox) and TBHP

(2013) Ryan J. DeLuca et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Hydrotrifluoromethylation of Unactivated Alkenes

(2013) Satoshi Mizuta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Anti-Markovnikov Hydroalkylation of Homoallylic Alcohols Bearing β-Fluorines

(2013) Xiaowei Lin et al.   ORGANIC LETTERS

Simple and clean synthesis of ketones from internal olefins using PdCl2/N,N-dimethylacetamide catalyst system

(2013) Takato Mitsudome et al.   TETRAHEDRON LETTERS

Overcoming the “Oxidant Problem”: Strategies to Use O2 as the Oxidant in Organometallic C–H Oxidation Reactions Catalyzed by Pd (and Cu)

(2012) Alison N. Campbell et al.   ACCOUNTS OF CHEMICAL RESEARCH

A “Renaissance” in Radical Trifluoromethylation

(2012) Armido Studer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Synthesis of Trifluoromethyl-substituted Diarylpyrrolines: Enantioselective Conjugate Cyanation of β-Aryl-β-trifluoromethyl-disubstituted Enones

(2012) Hiroyuki Kawai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trifluoromethylation of α-Haloketones

(2012) Petr Novák et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient and Highly Aldehyde Selective Wacker Oxidation

(2012) Peili Teo et al.   ORGANIC LETTERS

Copper-Catalyzed Oxidative Trifluoromethylation of Terminal Alkenes Using Nucleophilic CF3SiMe3: Efficient C(sp3)–CF3 Bond Formation

(2012) Lingling Chu et al.   ORGANIC LETTERS

Copper-Catalyzed Trifluoromethylation of Unactivated Olefins

(2011) Andrew T. Parsons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Broadly Applicable Copper Reagent for Trifluoromethylations and Perfluoroalkylations of Aryl Iodides and Bromides

(2011) Hiroyuki Morimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

Palladium(II)-Catalyzed Alkene Functionalization via Nucleopalladation: Stereochemical Pathways and Enantioselective Catalytic Applications

(2011) Richard I. McDonald et al.   CHEMICAL REVIEWS

Organic fluorine compounds: a great opportunity for enhanced materials properties

(2011) Ricarda Berger et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Friedel−Crafts Alkylation of Indoles with Trifluoroethylidene Malonates by Copper−Bis(oxazoline) Complexes: Construction of Trifluoromethyl-Substituted Stereogenic Tertiary Carbon Center

(2011) Lele Wen et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Trifluoromethylation of Terminal Alkenes through Allylic C–H Bond Activation

(2011) Jun Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed C(sp3)–C(sp3) Bond Formation Using a Hypervalent Iodine Reagent: An Efficient Allylic Trifluoromethylation

(2011) Xi Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

A [Pd]-mediated ω-alkynone cycloisomerization approach for the central tetrahydropyran unit and the synthesis of C(31)–C(48) fragment of aflastatin A

(2011) Sachin B. Narute et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Primary Alcohols from Terminal Olefins: Formal Anti-Markovnikov Hydration via Triple Relay Catalysis

(2011) G. Dong et al.   SCIENCE

Synthesis of β-Trifluoromethylated Δ1-Pyrrolines

(2010) Olivier Marrec et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalyst-Controlled Wacker-Type Oxidation of Protected Allylic Amines

(2010) Brian W. Michel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Functionalized Indoles with a Trifluoromethyl-Substituted Stereogenic Tertiary Carbon Atom Through an Enantioselective Friedel-Crafts Alkylation with β-Trifluoromethyl-α,β-enones

(2010) Gonzalo Blay et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Productive Merger of Iodonium Salts and Organocatalysis: A Non-photolytic Approach to the Enantioselective α-Trifluoromethylation of Aldehydes

(2010) Anna E. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzedortho-Trifluoromethylation of Arenes Using TFA as a Promoter

(2010) Xisheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Friedel−Crafts Reaction of β-Trifluoromethylated Acrylates with Pyrroles and Its Application to the Synthesis of Trifluorinated Heliotridane

(2010) Yiyong Huang et al.   ORGANIC LETTERS

Copper-Mediated Oxidative Trifluoromethylation of Boronic Acids

(2010) Lingling Chu et al.   ORGANIC LETTERS

The Mechanism of the Wacker Reaction: A Tale of Two Hydroxypalladations

(2009) John���A. Keith et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A perfect double role of CF3 groups in activating substrates and stabilizing adducts: the chiral Brønsted acid-catalyzed direct arylation of trifluoromethyl ketones

(2009) Jing Nie et al.   CHEMICAL COMMUNICATIONS

Recent advancements and challenges of palladiumII-catalyzed oxidation reactions with molecular oxygen as the sole oxidant

(2009) Keith M. Gligorich et al.   CHEMICAL COMMUNICATIONS

Aldehyde Selective Wacker Oxidations of Phthalimide Protected Allylic Amines: A New Catalytic Route to β3-Amino Acids

(2009) Barbara Weiner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A General and Efficient Catalyst System for a Wacker-Type Oxidation Using TBHP as the Terminal Oxidant: Application to Classically Challenging Substrates

(2009) Brian W. Michel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleophilic trifluoromethylation of arylidene Meldrum’s acids

(2009) Artem A. Zemtsov et al.   TETRAHEDRON LETTERS

Recent advances in enantioselective trifluoromethylation reactions

(2009) Norio Shibata et al.   TETRAHEDRON-ASYMMETRY

The Chemistry of Propargylic and Allylic Fluorides

(2008) M. Carmen Pacheco et al.   CHEMICAL REVIEWS

A first high enantiocontrol of an asymmetric tertiary carbon center attached with a fluoroalkyl group via Rh(I)-catalyzed conjugate addition reaction

(2008) Tsutomu Konno et al.   TETRAHEDRON LETTERS

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS