Local Transient Unfolding of Native State PAI-1 Associated with Serpin Metastability

Dissecting the Effect of RNA Aptamer Binding on the Dynamics of Plasminogen Activator Inhibitor 1 Using Hydrogen/Deuterium Exchange Mass Spectrometry

(2013) Morten B. Trelle et al.   ACS Chemical Biology

Hydrogen/Deuterium Exchange Mass Spectrometry Reveals Specific Changes in the Local Flexibility of Plasminogen Activator Inhibitor 1 upon Binding to the Somatomedin B Domain of Vitronectin

(2012) Morten Beck Trelle et al.   BIOCHEMISTRY

How the Serpin α1-Proteinase Inhibitor Folds

(2012) Klavs Dolmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Folding mechanism of the metastable serpin  1-antitrypsin

(2012) Y. Tsutsui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of Plasminogen Activator Inhibitor-1 in an Active Conformation with Normal Thermodynamic Stability

(2011) Jan K. Jensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serpin structure, function and dysfunction

(2011) J. A. HUNTINGTON   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Dynamic local unfolding in the serpin α-1 antitrypsin provides a mechanism for loop insertion and polymerization

(2011) Beena Krishnan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Plasminogen activator inhibitor-1 is an aggregate response factor with pleiotropic effects on cell signaling in vascular disease and the tumor microenvironment

(2010) Mark W. Gramling et al.   THROMBOSIS RESEARCH

Protein Hydrogen Exchange Measured at Single-Residue Resolution by Electron Transfer Dissociation Mass Spectrometry

(2009) Kasper D. Rand et al.   ANALYTICAL CHEMISTRY

Conformational Pathology of the Serpins: Themes, Variations, and Therapeutic Strategies

(2009) Bibek Gooptu et al.   Annual Review of Biochemistry

Biochemical properties of plasminogen activator inhibitor-1

(2009) Daniel Miotto Dupont   Frontiers in Bioscience-Landmark

Functional Unfolding of α1-Antitrypsin Probed by Hydrogen-Deuterium Exchange Coupled with Mass Spectrometry

(2009) Je-Hyun Baek et al.   MOLECULAR & CELLULAR PROTEOMICS

Protein structure and dynamics studied by mass spectrometry: H/D exchange, hydroxyl radical labeling, and related approaches

(2008) Lars Konermann et al.   JOURNAL OF MASS SPECTROMETRY