Prediction of a Ligand-Binding Niche within a Human Olfactory Receptor by Combining Site-Directed Mutagenesis with Dynamic Homology Modeling

Subunit Contributions to Insect Olfactory Receptor Function: Channel Block and Odorant Recognition

(2011) Andrew S. Nichols et al.   CHEMICAL SENSES

Modeling GPCR active state conformations: The β2-adrenergic receptor

(2011) Lisa M. Simpson et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The Mouse Eugenol Odorant Receptor: Structural and Functional Plasticity of a Broadly Tuned Odorant Binding Pocket

(2010) Olivia Baud et al.   BIOCHEMISTRY

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

(2010) B. Wu et al.   SCIENCE

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

(2010) E. Y. T. Chien et al.   SCIENCE

Activation of an Olfactory Receptor Inhibits Proliferation of Prostate Cancer Cells

(2009) Eva M. Neuhaus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GPCR 3D homology models for ligand screening: Lessons learned from blind predictions of adenosine A2a receptor complex

(2009) Vsevolod Katritch et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Activation of Pheromone-Sensitive Neurons Is Mediated by Conformational Activation of Pheromone-Binding Protein

(2008) John D. Laughlin et al.   CELL

Relationships Between Molecular Structure and Perceived Odor Quality of Ligands for a Human Olfactory Receptor

(2008) Guenhaël Sanz et al.   CHEMICAL SENSES

The Importance of Odorant Conformation to the Binding and Activation of a Representative Olfactory Receptor

(2008) Zita Peterlin et al.   CHEMISTRY & BIOLOGY

Simulations of a G protein-coupled receptor homology model predict dynamic features and a ligand binding site

(2008) Steffen Wolf et al.   FEBS LETTERS

Discovery of Novel Chemotypes to a G-Protein-Coupled Receptor through Ligand-Steered Homology Modeling and Structure-Based Virtual Screening

(2008) Claudio N. Cavasotto et al.   JOURNAL OF MEDICINAL CHEMISTRY

RosettaLigand Docking with Full Ligand and Receptor Flexibility

(2008) Ian W. Davis et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of a β1-adrenergic G-protein-coupled receptor

(2008) Tony Warne et al.   NATURE

Crystal structure of squid rhodopsin

(2008) Midori Murakami et al.   NATURE

Crystal structure of the ligand-free G-protein-coupled receptor opsin

(2008) Jung Hee Park et al.   NATURE

High-Potency Olfactory Receptor Agonists Discovered by Virtual High-Throughput Screening: Molecular Probes for Receptor Structure and Olfactory Function

(2008) Nicolas Triballeau et al.   NEURON

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE