From One-Photon to Two-Photon Probes: “Caged” Compounds, Actuators, and Photoswitches

Water-Soluble, Donor-Acceptor Biphenyl Derivatives in the 2-(o-Nitrophenyl)propyl Series: Highly Efficient Two-Photon Uncaging of the Neurotransmitter γ-Aminobutyric Acid at λ=800 nm

(2012) Loïc Donato et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Azobenzenes in a New Light-Switching In Vivo

(2012) Hermann A. Wegner   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Light-Controlled Tools

(2012) Clara Brieke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photochemical Modulation of Ras-Mediated Signal Transduction Using Caged Farnesyltransferase Inhibitors: Activation by One- and Two-Photon Excitation

(2012) Daniel Abate-Pella et al.   CHEMBIOCHEM

Increasing materials' response to two-photon NIR light via self-immolative dendritic scaffolds

(2012) Nadezda Fomina et al.   CHEMICAL COMMUNICATIONS

Computational design of improved two-photon active caging compounds based on nitrodibenzofuran

(2012) Andreas Dreuw et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

7-Amino coumarin based fluorescent phototriggers coupled with nano/bio-conjugated bonds: Synthesis, labeling and photorelease

(2012) Qiuning Lin et al.   JOURNAL OF MATERIALS CHEMISTRY

A glutamate switch controls voltage-sensitive phosphatase function

(2012) Lijun Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Optical Control of Endogenous Proteins with a Photoswitchable Conditional Subunit Reveals a Role for TREK1 in GABAB Signaling

(2012) Guillaume Sandoz et al.   NEURON

The donor–acceptor biphenyl platform: A versatile chromophore for the engineering of highly efficient two-photon sensitive photoremovable protecting groups

(2012) Alexandre Specht et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Applications of p-hydroxyphenacyl (pHP) and coumarin-4-ylmethyl photoremovable protecting groups

(2012) Richard S. Givens et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Dual Wavelength Photoactivation of cAMP- and cGMP-Dependent Protein Kinase Signaling Pathways

(2011) Melanie A. Priestman et al.   ACS Chemical Biology

Two-Photon Microscopy for Chemical Neuroscience

(2011) Graham C. R. Ellis-Davies   ACS Chemical Neuroscience

Optochemical Genetics

(2011) Timm Fehrentz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Optical switch probes and optical lock-in detection (OLID) imaging microscopy: high-contrast fluorescence imaging within living systems

(2011) Yuling Yan et al.   BIOCHEMICAL JOURNAL

The 64th Symposium of the Society for General Physiologists: optogenetics and superresolution microscopy take center stage: Figure 1.

(2011) Graham C.R. Ellis-Davies et al.   JOURNAL OF GENERAL PHYSIOLOGY

Three-dimensional holographic photostimulation of the dendritic arbor

(2011) Sunggu Yang et al.   Journal of Neural Engineering

Wavelength-Selective Caged Surfaces: How Many Functional Levels Are Possible?

(2011) Verónica San Miguel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multiphoton Reactive Surfaces Using Ruthenium(II) Photocleavable Cages

(2011) Verónica San Miguel et al.   LANGMUIR

Wavelength-Selective Uncaging of dA and dC Residues

(2011) Florian Schäfer et al.   ORGANIC LETTERS

Styryl Conjugated Coumarin Caged Alcohol: Efficient Photorelease by Either One-Photon Long Wavelength or Two-Photon NIR Excitation

(2011) Chunyan Bao et al.   ORGANIC LETTERS

Photodynamic therapy and two-photon bio-imaging applications of hydrophobic chromophores through amphiphilic polymer delivery

(2011) Thibault Gallavardin et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Synthesis and characterization of cell-permeant 6-nitrodibenzofuranyl-caged IP3

(2011) Srinivas Kantevari et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Spatial Distributions of GABA Receptors and Local Inhibition of Ca2+ Transients Studied with GABA Uncaging in the Dendrites of CA1 Pyramidal Neurons

(2011) Yuya Kanemoto et al.   PLoS One

Synthesis and photolytic evaluation of a nitroindoline-caged glycine with a side chain of high negative charge for use in neuroscience

(2011) George Papageorgiou et al.   TETRAHEDRON

Optical Control of Neuronal Activity

(2010) Stephanie Szobota et al.   Annual Review of Biophysics

Integrin-Targeting Block Copolymer Probes for Two-Photon Fluorescence Bioimaging

(2010) Sanchita Biswas et al.   BIOMACROMOLECULES

Two-photon uncaging: New prospects in neuroscience and cellular biology

(2010) D. Warther et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Two-photon microscope for multisite microphotolysis of caged neurotransmitters in acute brain slices

(2010) Bradley E. Losavio et al.   JOURNAL OF BIOMEDICAL OPTICS

1,1′-Azobis-1,2,3-triazole: A High-Nitrogen Compound with Stable N8Structure and Photochromism

(2010) Yu-Chuan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anticancer Drug Release from a Mesoporous Silica Based Nanophotocage Regulated by Either a One- or Two-Photon Process

(2010) Qiuning Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reversible Two-Photon Photoswitching and Two-Photon Imaging of Immunofunctionalized Nanoparticles Targeted to Cancer Cells

(2010) Ming-Qiang Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Probing Nitrobenzhydrol Uncaging Mechanisms Using FerriCast

(2010) Daniel P. Kennedy et al.   ORGANIC LETTERS

Improved Synthesis of the Two-Photon Caging Group 3-Nitro-2-Ethyldibenzofuran and Its Application to a Caged Thymidine Phosphoramidite

(2010) Hrvoje Lusic et al.   ORGANIC LETTERS

Recent advances in the photochemical control of protein function

(2010) Chad W. Riggsbee et al.   TRENDS IN BIOTECHNOLOGY

Illuminating the Chemistry of Life: Design, Synthesis, and Applications of “Caged” and Related Photoresponsive Compounds

(2009) Hsien-Ming Lee et al.   ACS Chemical Biology

A New Two-Photon-Sensitive Block Copolymer Nanocarrier

(2009) Jérôme Babin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two-Photon Absorption and the Design of Two-Photon Dyes

(2009) Miłosz Pawlicki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Light-mediated remote control of signaling pathways

(2009) Melanie A. Priestman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Photochemical tools to study dynamic biological processes

(2009) Alexandre Specht et al.   HFSP Journal

Laser photolysis of caged compounds at 405nm: Photochemical advantages, localisation, phototoxicity and methods for calibration

(2009) Federico F. Trigo et al.   JOURNAL OF NEUROSCIENCE METHODS

Laser photolysis of DPNI-GABA, a tool for investigating the properties and distribution of GABA receptors and for silencing neurons in situ

(2009) Federico F. Trigo et al.   JOURNAL OF NEUROSCIENCE METHODS

Substituent Effects on the Sensitivity of a Quinoline Photoremovable Protecting Group to One- and Two-Photon Excitation

(2009) M. Jarrett Davis et al.   JOURNAL OF ORGANIC CHEMISTRY

Resonance Raman Characterization of Different Forms of Ground-State 8-Bromo-7-hydroxyquinoline Caged Acetate in Aqueous Solutions

(2009) Hui-Ying An et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Caged Progesterone: A New Tool for Studying Rapid Nongenomic Actions of Progesterone

(2009) Funda Kilic et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Caged Progesterone: A New Tool for Studying Rapid Nongenomic Actions of Progesterone

(2009) Funda Kilic et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoinduced Nitric Oxide Release from a Hindered Nitrobenzene Derivative by Two-Photon Excitation

(2009) Kazuhiro Hishikawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Two-color, two-photon uncaging of glutamate and GABA

(2009) Srinivas Kantevari et al.   NATURE METHODS

RuBi-Glutamate: Two-photon and visible-light photoactivation of neurons and dendritic spines

(2009) Elodie Fino   Frontiers in Neural Circuits

A Caged Retinoic Acid for One- and Two-Photon Excitation in Zebrafish Embryos

(2008) Pierre Neveu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Engineering of Photoremovable Protecting Groups for Two-Photon Uncaging

(2008) Sylvestre Gug et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development of novel water-soluble photocleavable protective group and its application for design of photoresponsive paclitaxel prodrugs

(2008) Mayo Noguchi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Photolabile Glutamate Protecting Group with High One- and Two-Photon Uncaging Efficiencies

(2008) Sylvestre Gug et al.   CHEMBIOCHEM

Neurobiology with Caged Calcium

(2008) Graham C. R. Ellis-Davies   CHEMICAL REVIEWS

Multiphoton Absorbing Materials:  Molecular Designs, Characterizations, and Applications

(2008) Guang S. He et al.   CHEMICAL REVIEWS

Artificial Enzyme Catalysis Controlled and Driven by Light

(2008) Günther Knör   CHEMISTRY-A EUROPEAN JOURNAL

Two-photon micropatterning of amines within an agarose hydrogel

(2008) Ryan G. Wylie et al.   JOURNAL OF MATERIALS CHEMISTRY

Three-Dimensional Mapping of Unitary Synaptic Connections by Two-Photon Macro Photolysis of Caged Glutamate

(2008) Masanori Matsuzaki et al.   JOURNAL OF NEUROPHYSIOLOGY

Water-Soluble Two-Photon Absorbing Nitrosyl Complex for Light-Activated Therapy through Nitric Oxide Release

(2008) Qingdong Zheng et al.   MOLECULAR PHARMACEUTICS

Holographic photolysis of caged neurotransmitters

(2008) Christoph Lutz et al.   NATURE METHODS

Alcohol Uncaging with Fluorescence Reporting: Evaluation ofo-Acetoxyphenyl Methyloxazolone Precursors

(2008) Nathalie Gagey et al.   ORGANIC LETTERS

Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cells

(2008) G. Marriott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SLM microscopy: scanless two-photon imaging and photostimulation using spatial light modulators

(2008) Volodymyr Nikolenko   Frontiers in Neural Circuits