Structures of Class B G Protein-Coupled Receptors: Prospects for Drug Discovery

A Brief History of G-Protein Coupled Receptors (Nobel Lecture)

(2013) Robert J. Lefkowitz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Structural Basis of G-Protein-Coupled Receptor Signaling (Nobel Lecture)

(2013) Brian Kobilka   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Corticotropin-releasing factor 1 receptor antagonists: a patent review

(2013) John P Williams   EXPERT OPINION ON THERAPEUTIC PATENTS

Structure of class B GPCR corticotropin-releasing factor receptor 1

(2013) Kaspar Hollenstein et al.   NATURE

Structure of the human glucagon class B G-protein-coupled receptor

(2013) Fai Yiu Siu et al.   NATURE

Molecular signatures of G-protein-coupled receptors

(2013) A. J. Venkatakrishnan et al.   NATURE

The Seven Pillars of Molecular Pharmacology: GPCR Research Honored with Nobel Prize for Chemistry

(2012) Felix Hausch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure-Function of the G Protein–Coupled Receptor Superfamily

(2012) Vsevolod Katritch et al.   Annual Review of Pharmacology and Toxicology

Structural biology: Snapshot of an activated peptide receptor

(2012) Felix Hausch et al.   NATURE

Structure of the agonist-bound neurotensin receptor

(2012) Jim F. White et al.   NATURE

Quantitative pharmacological analysis of antagonist binding kinetics at CRF1 receptors in vitro and in vivo

(2011) Simeon J Ramsey et al.   BRITISH JOURNAL OF PHARMACOLOGY

Corticotropin releasing factor receptor antagonists for major depressive disorder

(2011) Marcelo Paez-Pereda et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Biomimetic Screening of Class-B G Protein-Coupled Receptors

(2011) Christian Devigny et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Progress in corticotropin-releasing factor-1 antagonist development

(2010) Eric P. Zorrilla et al.   DRUG DISCOVERY TODAY

Passing the baton in class B GPCRs: peptide hormone activation via helix induction?

(2009) Christoph Parthier et al.   TRENDS IN BIOCHEMICAL SCIENCES

Betablockers at Work: The Crystal Structure of the β2-Adrenergic Receptor

(2008) Felix Hausch   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION