Quantitative pharmacological analysis of antagonist binding kinetics at CRF1 receptors in vitro and in vivo

Pharmacodynamic-Pharmacokinetic Integration as a Guide to Medicinal Chemistry

(2011) Johan Gabrielsson et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Estimation of binding rate constants using a simultaneous mixed-effects method: application to monoamine transporter reuptake inhibitor reboxetine

(2010) Neil Benson et al.   BRITISH JOURNAL OF PHARMACOLOGY

Methodological Comparison of In Vitro Binding Parameter Estimation: Sequential vs. Simultaneous Non-linear Regression

(2010) C. Steven Ernest et al.   PHARMACEUTICAL RESEARCH

Optimising in vivo pharmacology studies—Practical PKPD considerations

(2010) Johan Gabrielsson et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Pharmacokinetic–pharmacodynamic reasoning in drug discovery and early development

(2009) Piet H Van Der Graaf et al.   Future Medicinal Chemistry

Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: Application to (R)-dimethindene occupancy of central histamine H1receptors

(2009) Siobhan Malany et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Target site occupancy: Emerging generalizations from clinical and preclinical studies

(2009) Sarah Grimwood et al.   PHARMACOLOGY & THERAPEUTICS

Residence Time of Receptor−Ligand Complexes and Its Effect on Biological Function

(2008) Peter J. Tummino et al.   BIOCHEMISTRY

Guide to Receptors and Channels (GRAC), 3rd edition

(2008) S P H Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Allosteric Ligands for the Corticotropin Releasing Factor Type 1 Receptor Modulate Conformational States Involved in Receptor Activation

(2008) S. R. J. Hoare et al.   MOLECULAR PHARMACOLOGY

Quantifying the association and dissociation rates of unlabelled antagonists at the muscarinic M3 receptor

(2006) Mark R Dowling et al.   BRITISH JOURNAL OF PHARMACOLOGY