Rapid and Efficient Trifluoromethylation of Aromatic and Heteroaromatic Compounds Using Potassium Trifluoroacetate Enabled by a Flow System

Mild and Rapid Pd-Catalyzed Cross-Coupling with Hydrazine in Continuous Flow: Application to the Synthesis of Functionalized Heterocycles

(2013) Andrew DeAngelis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sandmeyer Trifluoromethylation of Arenediazonium Tetrafluoroborates

(2013) Grégory Danoun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Continuous-Flow Synthesis of 1-Substituted Benzotriazoles from Chloronitrobenzenes and Amines in a CN Bond Formation/Hydrogenation/Diazotization/Cyclization Sequence

(2013) Mao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Promoted Sandmeyer Trifluoromethylation Reaction

(2013) Jian-Jun Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluoroform-Derived CuCF3for Low-Cost, Simple, Efficient, and Safe Trifluoromethylation of Aryl Boronic Acids in Air

(2012) Petr Novák et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Continuous Synthesis and Purification by Direct Coupling of a Flow Reactor with Simulated Moving-Bed Chromatography

(2012) Alexander G. O'Brien et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

On Being Green: Can Flow Chemistry Help?

(2012) Steven V. Ley   CHEMICAL RECORD

Recent Developments on the Trifluoromethylation of (Hetero)Arenes

(2012) Xiao-Feng Wu et al.   Chemistry-An Asian Journal

Flash Flow Pyrolysis: Mimicking Flash Vacuum Pyrolysis in a High-Temperature/High-Pressure Liquid-Phase Microreactor Environment

(2012) David Cantillo et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd(II)-Catalyzed Ortho Trifluoromethylation of Arenes and Insights into the Coordination Mode of Acidic Amide Directing Groups

(2012) Xing-Guo Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Continuous-Flow Synthesis of Monoarylated Acetaldehydes Using Aryldiazonium Salts

(2012) Natalia Chernyak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Merging Visible-Light Photocatalysis and Transition-Metal Catalysis in the Copper-Catalyzed Trifluoromethylation of Boronic Acids with CF3I

(2012) Yingda Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Towards a Practical and Efficient Copper-Catalyzed Trifluoromethylation of Aryl Halides

(2012) Thomas Schareina et al.   TOPICS IN CATALYSIS

Highly Selective Trifluoromethylation of 1,3-Disubstituted Arenes through Iridium-Catalyzed Arene Borylation

(2011) Tianfei Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Traceless Solid-Phase Synthesis of Trifluoromethylarenes

(2011) Marion Döbele et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Broadly Applicable Copper Reagent for Trifluoromethylations and Perfluoroalkylations of Aryl Iodides and Bromides

(2011) Hiroyuki Morimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Mediated Trifluoromethylation of Heteroaromatic Compounds by Trifluoromethyl Sulfonium Salts

(2011) Cheng-Pan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ten key issues in modern flow chemistry

(2011) Jens Wegner et al.   CHEMICAL COMMUNICATIONS

Recent advances in micro reaction technology

(2011) Charlotte Wiles et al.   CHEMICAL COMMUNICATIONS

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

Copper-Catalyzed Trifluoromethylation of Aryl Iodides with Potassium (Trifluoromethyl)trimethoxyborate

(2011) Thomas Knauber et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mechanistic and Computational Studies of Oxidatively-Induced Aryl−CF3Bond-Formation at Pd: Rational Design of Room Temperature Aryl Trifluoromethylation

(2011) Nicholas D. Ball et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Cupration of Fluoroform

(2011) Alessandro Zanardi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Direct C–H Oxidative Trifluoromethylation of Heteroarenes

(2011) Lingling Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis

(2011) David A. Nagib et al.   NATURE

Cooperative Effect of Silver in Copper-Catalyzed Trifluoromethylation of Aryl Iodides Using Me3SiCF3

(2011) Zhiqiang Weng et al.   ORGANOMETALLICS

Innate C-H trifluoromethylation of heterocycles

(2011) Y. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Ligand-Free Copper-Catalyzed Decarboxylative Trifluoromethylation of Aryliodides with Sodium Trifluoroacetate Using Ag2O as a Promoter

(2011) Yaming Li et al.   SYNLETT

Trifluoromethylation of aryl and heteroaryl halides

(2011) Sudipta Roy et al.   TETRAHEDRON

Accessing Stereochemically Rich Sultams via Microwave-assisted, Continuous-flow Organic Synthesis (MACOS) Scale-out

(2011) Michael G. Organ et al.   Journal of Flow Chemistry

Investigation of Indium Phosphide Nanocrystal Synthesis Using a High-Temperature and High-Pressure Continuous Flow Microreactor

(2010) Jinyoung Baek et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Real-Time Product Switching Using a Twin Catalyst System for the Hydrogenation of Furfural in Supercritical CO2

(2010) James G. Stevens et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of 5-Substituted 1H-Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High-Temperature Microreactor Approach

(2010) Bernhard Gutmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Catalyzed Trifluoromethylation of Aryl Halides

(2010) Rylan J. Lundgren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Continuous Flow Coupling and Decarboxylation Reactions Promoted by Copper Tubing

(2010) Yun Zhang et al.   ORGANIC LETTERS

Kinetic and Scale-Up Investigations of Epoxide Aminolysis in Microreactors at High Temperatures and Pressures

(2010) Nikolay Zaborenko et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides

(2010) E. J. Cho et al.   SCIENCE

Aromatic trifluoromethylation catalytic in copper

(2009) Masahiro Oishi et al.   CHEMICAL COMMUNICATIONS

An efficient and transition metal free protocol for the transfer hydrogenation of ketones as a continuous flow process

(2009) Jörg Sedelmeier et al.   GREEN CHEMISTRY

The solid complex Zn(CF3)Br·2DMF as an alternative reagent for the preparation of both, trifluoromethyl and pentafluoroethyl copper, CuCF3 and CuC2F5

(2009) Mikhail M. Kremlev et al.   JOURNAL OF FLUORINE CHEMISTRY

Flash Chemistry: Fast Chemical Synthesis by Using Microreactors

(2008) Jun-ichi Yoshida et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Advances in Electrophilic CF3-Transfer Using Hypervalent Iodine(III) Reagents

(2008) Iris Kieltsch et al.   CHIMIA

Active Trifluoromethylating Agents from Well-Defined Copper(I)−CF3Complexes

(2008) Galyna G. Dubinina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Studies on the Copper-CatalyzedN-Arylation of Amides

(2008) Eric R. Strieter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS