Enzymatic “Click” Ligation: Selective Cysteine Modification in Polypeptides Enabled by Promiscuous Glutathione S-Transferase

Ligand-Directed Selective Protein Modification Based on Local Single-Electron-Transfer Catalysis

(2013) Shinichi Sato et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Perfluoroaryl-Cysteine SNAr Chemistry Approach to Unprotected Peptide Stapling

(2013) Alexander M. Spokoyny et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A novel approach to the site-selective dual labelling of a protein via chemoselective cysteine modification

(2013) Ramiz I. Nathani et al.   Chemical Science

Orthogonality in organic, polymer, and supramolecular chemistry: from Merrifield to click chemistry

(2012) Chun-Ho Wong et al.   CHEMICAL COMMUNICATIONS

Protein Thioester Synthesis Enabled by Sortase

(2012) Jingjing J. Ling et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes

(2012) P. S. Coelho et al.   SCIENCE

Biocatalytic Promiscuity

(2011) Maria Svedendahl Humble et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Contemporary strategies for peptide macrocyclization

(2011) Christopher J. White et al.   Nature Chemistry

Biomimetic Catalysis

(2011) Louis Marchetti et al.   ACS Catalysis

An Unexpected Example of Protein-Templated Click Chemistry

(2010) Takayoshi Suzuki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions

(2010) Manfred T. Reetz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

Multicolor Protein Labeling in Living Cells Using Mutant β-Lactamase-Tag Technology

(2010) Shuji Watanabe et al.   BIOCONJUGATE CHEMISTRY

Cu-free click cycloaddition reactions in chemical biology

(2010) John C. Jewett et al.   CHEMICAL SOCIETY REVIEWS

Protein Chemical Modification on Endogenous Amino Acids

(2010) Emmanuel Baslé et al.   CHEMISTRY & BIOLOGY

What makes an enzyme promiscuous?

(2010) Ann Babtie et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A fluorophore ligase for site-specific protein labeling inside living cells

(2010) C. Uttamapinant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Click Chemistry beyond Metal-Catalyzed Cycloaddition

(2009) C. Remzi Becer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology

(2009) Justin M. Chalker et al.   Chemistry-An Asian Journal

Clicking Pentafluorostyrene Copolymers: Synthesis, Nanoprecipitation, and Glycosylation

(2009) C. Remzi Becer et al.   MACROMOLECULES

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

Chemoselective Ligation and Modification Strategies for Peptides and Proteins

(2008) Christian P. R. Hackenberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Native Chemical Ligation at Valine: A Contribution to Peptide and Glycopeptide Synthesis

(2008) Jin Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Native Chemical Ligation at Valine

(2008) Christian Haase et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid Oxime and Hydrazone Ligations with Aromatic Aldehydes for Biomolecular Labeling

(2008) Anouk Dirksen et al.   BIOCONJUGATE CHEMISTRY

Chemoselective modification of proteins: hitting the target

(2008) Isaac S. Carrico   CHEMICAL SOCIETY REVIEWS

Facile Conversion of Cysteine and Alkyl Cysteines to Dehydroalanine on Protein Surfaces: Versatile and Switchable Access to Functionalized Proteins

(2008) Gonçalo J. L. Bernardes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Disparate proteome reactivity profiles of carbon electrophiles

(2008) Eranthie Weerapana et al.   Nature Chemical Biology

The exploration of macrocycles for drug discovery — an underexploited structural class

(2008) Edward M. Driggers et al.   NATURE REVIEWS DRUG DISCOVERY