Exploring an Orbitrap Analyzer for the Characterization of Intact Antibodies by Native Mass Spectrometry

Automatic Disulfide Bond Assignment Using a1Ion Screening by Mass Spectrometry for Structural Characterization of Protein Pharmaceuticals

(2012) Sheng-Yu Huang et al.   ANALYTICAL CHEMISTRY

Qualitative and Semiquantitative Analysis of Composite Mixtures of Antibodies by Native Mass Spectrometry

(2012) Sara Rosati et al.   ANALYTICAL CHEMISTRY

Biosimilar, Biobetter, and Next Generation Antibody Characterization by Mass Spectrometry

(2012) Alain Beck et al.   ANALYTICAL CHEMISTRY

Native Intact Mass Determination of Antibodies Conjugated with Monomethyl Auristatin E and F at Interchain Cysteine Residues

(2012) John F. Valliere-Douglass et al.   ANALYTICAL CHEMISTRY

An innovative approach for the characterization of the isoforms of a monoclonal antibody product

(2012) Shanmuuga Sundaram et al.   mAbs

High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies

(2012) Rebecca J Rose et al.   NATURE METHODS

Unit Mass Baseline Resolution for an Intact 148 kDa Therapeutic Monoclonal Antibody by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

(2011) Santosh G. Valeja et al.   ANALYTICAL CHEMISTRY

Antibody-based therapeutics to watch in 2011

(2011) Janice M. Reichert   mAbs

Quantitative Analysis of the Interaction Strength and Dynamics of Human IgG4 Half Molecules by Native Mass Spectrometry

(2011) Rebecca J. Rose et al.   STRUCTURE

Glycan profiling of monoclonal antibodies using zwitterionic-type hydrophilic interaction chromatography coupled with electrospray ionization mass spectrometry detection

(2010) Lea Mauko et al.   ANALYTICAL BIOCHEMISTRY

Resolving Disulfide Structural Isoforms of IgG2 Monoclonal Antibodies by Ion Mobility Mass Spectrometry

(2010) Dhanashri Bagal et al.   ANALYTICAL CHEMISTRY

Generation of stable cell clones expressing mixtures of human antibodies

(2010) John de Kruif et al.   BIOTECHNOLOGY AND BIOENGINEERING

Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding

(2010) Damian Houde et al.   MOLECULAR & CELLULAR PROTEOMICS

Enhanced antibody half-life improves in vivo activity

(2010) Jonathan Zalevsky et al.   NATURE BIOTECHNOLOGY

Mass Spectrometric Analysis of Intact Human Monoclonal Antibody Aggregates Fractionated by Size-Exclusion Chromatography

(2010) Başak Kükrer et al.   PHARMACEUTICAL RESEARCH

Extending Mass Spectrometry Contribution to Therapeutic Monoclonal Antibody Lead Optimization: Characterization of Immune Complexes Using Noncovalent ESI-MS

(2009) Cédric Atmanene et al.   ANALYTICAL CHEMISTRY

Mass measurement and top-down HPLC/MS analysis of intact monoclonal antibodies on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer

(2009) Pavel V. Bondarenko et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Electrospray ionization quadrupole ion-mobility time-of-flight mass spectrometry as a tool to distinguish the lot-to-lot heterogeneity in N-glycosylation profile of the therapeutic monoclonal antibody trastuzumab

(2009) Carola W. N. Damen et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Effects of antibody affinity and antigen valence on molecular forms of immune complexes

(2009) Masayuki Oda et al.   MOLECULAR IMMUNOLOGY

Mass Spectrometric Determination of Disulfide Linkages in Recombinant Therapeutic Proteins Using Online LC−MS with Electron-Transfer Dissociation

(2008) Shiaw-Lin Wu et al.   ANALYTICAL CHEMISTRY

The way forward, enhanced characterization of therapeutic antibody glycosylation: Comparison of three level mass spectrometry-based strategies

(2008) Elsa Wagner-Rousset et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Mass spectrometry for structural characterization of therapeutic antibodies

(2008) Zhongqi Zhang et al.   MASS SPECTROMETRY REVIEWS

Native mass spectrometry: a bridge between interactomics and structural biology

(2008) Albert J R Heck   NATURE METHODS