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Title
The Stereochemical Course and Mechanism of the IspH Reaction
Authors
Keywords
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Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 51, Issue 17, Pages 4053-4057
Publisher
Wiley
Online
2012-03-12
DOI
10.1002/anie.201201110
References
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Related references
Note: Only part of the references are listed.- Mechanistic Studies of an IspH-Catalyzed Reaction: Implications for Substrate Binding and Protonation in the Biosynthesis of Isoprenoids
- (2011) Wei-chen Chang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Biosynthesis of Isoprene Units: Mössbauer Spectroscopy of Substrate and Inhibitor Binding to the [4Fe-4S] Cluster of the LytB/IspH Enzyme
- (2011) Annegret Ahrens-Botzong et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2011) Youli Xiao et al. CHEMBIOCHEM
- Synthesis of Deuterated Mevalonolactone Isotopomers
- (2011) Jeroen S. Dickschat et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Crystal Structures of Mutant IspH Proteins Reveal a Rotation of the Substrate's Hydroxymethyl Group during Catalysis
- (2011) Ingrid Span et al. JOURNAL OF MOLECULAR BIOLOGY
- Pyridine Inhibitor Binding to the 4Fe-4S ProteinA. aeolicusIspH (LytB): A HYSCORE Investigation
- (2011) Weixue Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- An ENDOR and HYSCORE Investigation of a Reaction Intermediate in IspG (GcpE) Catalysis
- (2011) Weixue Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Isoprenoids in three-dimensional space: the stereochemistry of terpene biosynthesis
- (2011) Jeroen S. Dickschat NATURAL PRODUCT REPORTS
- Study of IspH, a Key Enzyme in the Methylerythritol Phosphate Pathway Using Fluoro-Substituted Substrate Analogues
- (2011) Youli Xiao et al. ORGANIC LETTERS
- Targeting Isoprenoid Biosynthesis for Drug Discovery: Bench to Bedside
- (2010) Eric Oldfield ACCOUNTS OF CHEMICAL RESEARCH
- Inhibition of the Fe4S4-Cluster-Containing Protein IspH (LytB): Electron Paramagnetic Resonance, Metallacycles, and Mechanisms
- (2010) Ke Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Paramagnetic Intermediates of (E)-4-Hydroxy-3-methylbut-2-enyl Diphosphate Synthase (GcpE/IspG) under Steady-State and Pre-Steady-State Conditions
- (2010) Weiya Xu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Organometallic mechanism of action and inhibition of the 4Fe-4S isoprenoid biosynthesis protein GcpE (IspG)
- (2010) W. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bioorganometallic mechanism of action, and inhibition, of IspH
- (2010) W. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of Active IspH Enzyme fromEscherichia coliProvides Mechanistic Insights into Substrate Reduction
- (2009) Tobias Gräwert et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Revisiting the IspH Catalytic System in the Deoxyxylulose Phosphate Pathway: Achieving High Activity
- (2009) Youli Xiao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Isoprenoid Biosynthesis via the MEP Pathway:In VivoMössbauer Spectroscopy Identifies a [4Fe-4S]2+Center with Unusual Coordination Sphere in the LytB Protein
- (2009) Myriam Seemann et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Probing the reaction mechanism of IspH protein by x-ray structure analysis
- (2009) T. Grawert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IspH Protein of the Deoxyxylulose Phosphate Pathway: Mechanistic Studies with C1-Deuterium-Labeled Substrate and Fluorinated Analogue
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- Mechanistic Studies of IspH in the Deoxyxylulose Phosphate Pathway: Heterolytic C−O Bond Cleavage at C4Position
- (2008) Youli Xiao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure of (E)-4-Hydroxy-3-methyl-but-2-enyl Diphosphate Reductase, the Terminal Enzyme of the Non-Mevalonate Pathway
- (2008) Ingo Rekittke et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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