Mechanistic Studies of an IspH-Catalyzed Reaction: Implications for Substrate Binding and Protonation in the Biosynthesis of Isoprenoids

Convergent strategies in biosynthesis

(2011) Tohru Dairi et al.   NATURAL PRODUCT REPORTS

Targeting Isoprenoid Biosynthesis for Drug Discovery: Bench to Bedside

(2010) Eric Oldfield   ACCOUNTS OF CHEMICAL RESEARCH

Reductive Dehydroxylation of Allyl Alcohols by IspH Protein

(2010) Tobias Gräwert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibition of the Fe4S4-Cluster-Containing Protein IspH (LytB): Electron Paramagnetic Resonance, Metallacycles, and Mechanisms

(2010) Ke Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Structure of Formaldehyde-Inhibited Xanthine Oxidase Determined by 35 GHz2H ENDOR Spectroscopy

(2010) Muralidharan Shanmugam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bioorganometallic mechanism of action, and inhibition, of IspH

(2010) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of Active IspH Enzyme fromEscherichia coliProvides Mechanistic Insights into Substrate Reduction

(2009) Tobias Gräwert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Revisiting the IspH Catalytic System in the Deoxyxylulose Phosphate Pathway: Achieving High Activity

(2009) Youli Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Isoprenoid Biosynthesis via the MEP Pathway:In VivoMössbauer Spectroscopy Identifies a [4Fe-4S]2+Center with Unusual Coordination Sphere in the LytB Protein

(2009) Myriam Seemann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Probing the reaction mechanism of IspH protein by x-ray structure analysis

(2009) T. Grawert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IspH Protein of the Deoxyxylulose Phosphate Pathway: Mechanistic Studies with C1-Deuterium-Labeled Substrate and Fluorinated Analogue

(2008) Youli Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic Studies of IspH in the Deoxyxylulose Phosphate Pathway:  Heterolytic C−O Bond Cleavage at C4Position

(2008) Youli Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of (E)-4-Hydroxy-3-methyl-but-2-enyl Diphosphate Reductase, the Terminal Enzyme of the Non-Mevalonate Pathway

(2008) Ingo Rekittke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY