N-Heterocyclic Carbene Catalyzed Homoenolate-Addition Reaction of Enals and Nitroalkenes: Asymmetric Synthesis of 5-Carbon-Synthon δ-Nitroesters

Primary Amine-Thioureas with Improved Catalytic Properties for “Difficult” Michael Reactions: Efficient Organocatalytic Syntheses of (S)-Baclofen, (R)-Baclofen and (S)-Phenibut

(2012) Michail Tsakos et al.   ADVANCED SYNTHESIS & CATALYSIS

Activation of 1,2-Keto Esters with Takemoto’s Catalyst toward Michael Addition to Nitroalkenes

(2012) Wilfried Raimondi et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Intermolecular Stetter Reactions of Enolizable Aldehydes with Nitrostyrenes: Computational Study Provides Insight into the Success of the Catalyst

(2012) Daniel A. DiRocco et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polymer-Supported Enantioselective Bifunctional Catalysts for Nitro-Michael Addition of Ketones and Aldehydes

(2012) Lital Tuchman-Shukron et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Heterocyclic Carbene Catalyzed Intramolecular Hydroacylation of Activated Alkynes: Synthesis of Chromones

(2011) Seenuvasan Vedachalam et al.   ADVANCED SYNTHESIS & CATALYSIS

Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters

(2011) Daniel T. Cohen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly diastereo- and enantioselective NHC-catalyzed [3+2] annulation of enals and isatins

(2011) Li-Hui Sun et al.   CHEMICAL COMMUNICATIONS

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Organocatalyzed Michael Addition of Aldehydes to Nitro Alkenes - Generally Accepted Mechanism Revisited and Revised

(2011) Krystyna Patora-Komisarska et al.   HELVETICA CHIMICA ACTA

N-Heterocyclic Carbene-Mediated Oxidative Esterification of Aldehydes: Ester Formation and Mechanistic Studies

(2011) Biswajit Maji et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis oftrans-γ-Lactams

(2011) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Intermolecular Stetter Reaction of Enals with Nitroalkenes: Enhancement of Catalytic Efficiency through Bifunctional Additives

(2011) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of 2,6-cis- and 2,6-trans-Piperidines through Organocatalytic Aza-Michael Reactions: A Facile Synthesis of (+)-Myrtine and (−)-Epimyrtine

(2011) Yongcheng Ying et al.   ORGANIC LETTERS

NHC-Catalyzed/Titanium(IV)−Mediated Highly Diastereo- and Enantioselective Dimerization of Enals

(2011) Daniel T. Cohen et al.   ORGANIC LETTERS

N-Heterocyclic Carbene Catalyzed C-Glycosylation: A Concise Approach from Stetter Reaction

(2011) Seenuvasan Vedachalam et al.   ORGANIC LETTERS

Organocatalytic Approach to Polysubstituted Piperidines and Tetrahydropyrans

(2011) You Wang et al.   ORGANIC LETTERS

N-Heterocyclic carbene (NHC) catalyzed annulation of enals and vinyl ketones: a novel synthesis of [2H]-pyranones

(2011) Vijay Nair et al.   TETRAHEDRON LETTERS

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

Prolylprolinol-Catalyzed Asymmetric Michael Addition of Aliphatic Aldehydes to Nitroalkenes

(2010) Dengfu Lu et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalyzed Conjugate Addition of Carbonyl Compounds to Nitrodienes/Nitroenynes and Synthetic Applications

(2010) Sébastien Belot et al.   ADVANCED SYNTHESIS & CATALYSIS

Pyrrolidinyl-Camphor Derivatives as a New Class of Organocatalyst for Direct Asymmetric Michael Addition of Aldehydes and Ketones to β-Nitroalkenes

(2010) Ying-Fang Ting et al.   CHEMISTRY-A EUROPEAN JOURNAL

Multiple-Organocatalyst-Promoted Cascade Reaction: A Fast and Efficient Entry into Fully Substituted Piperidines

(2010) Yao Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral Bifunctional Thiourea-Catalyzed Enantioselective Michael Addition of Ketones to Nitrodienes

(2010) Hai Ma et al.   JOURNAL OF ORGANIC CHEMISTRY

CooperativeN-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenolates

(2010) Benoit Cardinal-David et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereo- and Enantioselective Conjugate Addition of α-Ketoesters to Nitroalkenes Catalyzed by a Chiral Ni(OAc)2Complex under Mild Conditions

(2010) Ayako Nakamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to γ-lactams

(2010) Dustin E. A. Raup et al.   Nature Chemistry

A novel pseudo four component reaction involving homoenolate for the synthesis of γ-aminobutyric acid (GABA) derivatives

(2010) Vijay Nair et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

N-Heterocyclic carbene-catalyzed (NHC) three-component domino reactions: highly stereoselective synthesis of functionalized acyclic ε-ketoesters

(2010) Jianze Ma et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective and Regiodivergent Copper-Catalyzed Conjugate Addition of Trialkylaluminium Reagents to Extended Nitro-Michael Acceptors

(2010) Matthieu Tissot et al.   ORGANIC LETTERS

Enantio- and Diastereoselective Synthesis of Piperidines by Coupling of Four Components in a “One-Pot” Sequence Involving Diphenylprolinol Silyl Ether Mediated Michael Reaction

(2010) Tatsuya Urushima et al.   ORGANIC LETTERS

Highly Diastereo- and Enantioselective Organocatalytic Michael Addition of α-Ketoamides to Nitroalkenes

(2010) Olivier Baslé et al.   ORGANIC LETTERS

syn-Selective Catalytic Asymmetric 1,4-Addition of α-Ketoanilides to Nitroalkenes under Dinuclear Nickel Catalysis

(2010) Yingjie Xu et al.   ORGANIC LETTERS

Asymmetric organocatalytic synthesis of γ-nitrocarbonyl compounds through Michael and Domino reactions

(2010) David Roca-Lopez et al.   TETRAHEDRON-ASYMMETRY

Asymmetric conjugate addition of α-keto esters to nitroolefins catalyzed by chiral CuII hydroxo complexes

(2010) Ayako Nakamura et al.   TETRAHEDRON-ASYMMETRY

Organocatalytic Regio- and Stereoselective Inverse-Electron-Demand Aza-Diels-Alder Reaction of α,β-Unsaturated Aldehydes andN-Tosyl-1-aza-1,3-butadienes

(2009) Bo Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Unprecedented Scaffold Diversity

(2009) Warren R. J. D. Galloway et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tripeptides of the Type H-D-Pro-Pro-Xaa-NH2as Catalysts for Asymmetric 1,4-Addition Reactions: Structural Requirements for High Catalytic Efficiency

(2009) Markus Wiesner et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Asymmetric Intermolecular Stetter Reaction of Heterocyclic Aldehydes with Nitroalkenes: Backbone Fluorination Improves Selectivity

(2009) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel Nucleophilic Heterocyclic Carbene Mediated Stereoselective Conjugate Addition of Enals to Nitrostyrenes via Homoenolate§

(2009) Vijay Nair et al.   ORGANIC LETTERS

Nucleophilic Heterocyclic Carbene Catalyzed Annulation of Enals to Chalcones in Methanol: A Stereoselective Synthesis of Highly Functionalized Cyclopentanes§

(2009) Vijay Nair et al.   ORGANIC LETTERS

N-Heterocyclic Carbene-Catalyzed Intramolecular Aldehyde−Nitrile Cross Coupling: An Easy Access to 3- Aminochromones†

(2009) Seenuvasan Vedachalam et al.   ORGANIC LETTERS

Synthesis of Natural-Product-Like Molecules with Over Eighty Distinct Scaffolds

(2008) Daniel Morton et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in carbon–carbon bond-forming reactions involving homoenolates generated by NHC catalysis

(2008) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Cyclic Ketimines as Superior Electrophiles for NHC-Catalyzed Homoenolate Additions with Broad Scope and Low Catalyst Loadings

(2008) Michael Rommel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Amination of Homoenolates Catalyzed byN-Heterocyclic Carbenes

(2008) Audrey Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Diastereo- and Enantioselective Additions of Homoenolates to Nitrones Catalyzed byN-Heterocyclic Carbenes

(2008) Eric M. Phillips et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Organocatalytic Conjugate Addition of Aldehydes to Nitrodienes

(2008) Sébastien Belot et al.   ORGANIC LETTERS

Organocatalytic Synthesis ofN-Phenylisoxazolidin-5-ones and a One-Pot Synthesis of β-Amino Acid Esters

(2008) Jayasree Seayad et al.   ORGANIC LETTERS

Highly Efficient Catalytic System for Enantioselective Michael Addition of Aldehydes to Nitroalkenes in Water

(2007) Shaolin Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective synthesis of spirocyclopentanones viaN-heterocyclic carbene-catalyzed reactions of enals and dienones

(2007) Vijay Nair et al.   CHEMICAL COMMUNICATIONS

Enantioselective, NHC-Catalyzed Bicyclo-β-Lactam Formation via Direct Annulations of Enals and UnsaturatedN-Sulfonyl Ketimines

(2007) Ming He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY