Pro-inflammatory obesity in aged cannabinoid-2 receptor-deficient mice

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

A decade of progress in adipose tissue macrophage biology

(2014) Andrea A. Hill et al.   IMMUNOLOGICAL REVIEWS

Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress

(2014) Georgia E. Hodes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-Inducible Factor 1 Regulates Heat and Cold Pain Sensitivity and Persistence

(2013) Maike Kanngiesser et al.   ANTIOXIDANTS & REDOX SIGNALING

The Origins and Drivers of Insulin Resistance

(2013) Andrew M.F. Johnson et al.   CELL

Changes in Adipose Tissue Macrophages and T Cells During Aging

(2013) Sanjay K. Garg et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Anandamide deficiency and heightened neuropathic pain in aged mice

(2013) Philipp Bishay et al.   NEUROPHARMACOLOGY

Ghrelin-Induced Orexigenic Effect in Rats Depends on the Metabolic Status and Is Counteracted by Peripheral CB1 Receptor Antagonism

(2013) Francisco Alen et al.   PLoS One

Simultaneous and sensitive LC–MS/MS determination of tetrahydrocannabinol and metabolites in human plasma

(2012) N. Ferreirós et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Role of interleukin-6 in stress, sleep, and fatigue

(2012) Nicolas Rohleder et al.   Annals of the New York Academy of Sciences

Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice

(2012) Pierre Cardinal et al.   ENDOCRINOLOGY

Anti-obesity effects of the combined administration of CB1 receptor antagonist rimonabant and melanin-concentrating hormone antagonist SNAP-94847 in diet-induced obese mice

(2012) A N A Verty et al.   INTERNATIONAL JOURNAL OF OBESITY

CB1 blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans

(2012) R Bergholm et al.   INTERNATIONAL JOURNAL OF OBESITY

Overexpression of Cannabinoid CB2 Receptor in the Brain Induces Hyperglycaemia and a Lean Phenotype in Adult Mice

(2012) S. Y. Romero-Zerbo et al.   JOURNAL OF NEUROENDOCRINOLOGY

Targeted estrogen delivery reverses the metabolic syndrome

(2012) Brian Finan et al.   NATURE MEDICINE

Estrogen Receptors and the Metabolic Network

(2011) Rodrigo P.A. Barros et al.   Cell Metabolism

Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice

(2011) K S Bell-Anderson et al.   INTERNATIONAL JOURNAL OF OBESITY

Myeloid-specific estrogen receptor   deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development

(2011) V. Ribas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10−/− mice by attenuating the activation of T cells and promoting their apoptosis

(2011) Udai P. Singh et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype

(2010) Galina Burdyga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Pro-Inflammatory CD11c+CD206+ Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity

(2010) J. M. Wentworth et al.   DIABETES

Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age

(2010) J. Agudo et al.   DIABETOLOGIA

Bimodal control of stimulated food intake by the endocannabinoid system

(2010) Luigi Bellocchio et al.   NATURE NEUROSCIENCE

R-Flurbiprofen Reduces Neuropathic Pain in Rodents by Restoring Endogenous Cannabinoids

(2010) Philipp Bishay et al.   PLoS One

The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis

(2009) Alfiya Akhmetshina et al.   ARTHRITIS AND RHEUMATISM

Depletion of Liver Kupffer Cells Prevents the Development of Diet-Induced Hepatic Steatosis and Insulin Resistance

(2009) W. Huang et al.   DIABETES

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

(2009) S. Fujisaka et al.   DIABETES

The cannabinoid receptor type 2 promotes cardiac myocyte and fibroblast survival and protects against ischemia/reperfusion-induced cardiomyopathy

(2009) Nicole Defer et al.   FASEB JOURNAL

Cannabinoid CB2receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington's disease

(2009) Onintza Sagredo et al.   GLIA

Metabolic responses to long-term pharmacological inhibition of CB1-receptor activity in mice in relation to dietary fat composition

(2009) A H Koolman et al.   INTERNATIONAL JOURNAL OF OBESITY

Peripherally acting CB1-receptor antagonist: the relative importance of central and peripheral CB1 receptors in adiposity control

(2009) M-H Son et al.   INTERNATIONAL JOURNAL OF OBESITY

CANnabinoid Receptor Type 2 Activation Induces a Microglial Anti-Inflammatory Phenotype and Reduces Migration via MKP Induction and ERK Dephosphorylation

(2009) Edgar Alfonso Romero-Sandoval et al.   Molecular Pain

CB1 antagonists for obesity—what lessons have we learned from rimonabant?

(2009) Vincenzo Di Marzo et al.   Nature Reviews Endocrinology

Food Intake-independent Effects of CB1 Antagonism on Glucose and Lipid Metabolism

(2009) Daniela Cota et al.   Obesity

Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis

(2009) Vanessa Deveaux et al.   PLoS One

The Lipid Messenger OEA Links Dietary Fat Intake to Satiety

(2008) Gary J. Schwartz et al.   Cell Metabolism

Small-fibre involvement in diabetic patients with neuropathic foot pain

(2008) E. Vlckova-Moravcova et al.   DIABETIC MEDICINE

Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors

(2008) V. Di Marzo et al.   DIABETOLOGIA

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice

(2008) Douglas Osei-Hyiaman et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of cannabinoid CB2 receptor negatively regulates IL-12p40 production in murine macrophages: role of IL-10 and ERK1/2 kinase signaling

(2005) Fernando Correa et al.   BRITISH JOURNAL OF PHARMACOLOGY