The Triggering Receptor Expressed on Myeloid Cells 2: “TREM-ming” the Inflammatory Component Associated with Alzheimer's Disease

2012 Alzheimer’s disease facts and figures

(2012)   Alzheimers & Dementia

Is the Amyloid Hypothesis of Alzheimer's disease therapeutically relevant?

(2012) Andrew F. Teich et al.   BIOCHEMICAL JOURNAL

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Using Exome Sequencing to Reveal Mutations in TREM2 Presenting as a Frontotemporal Dementia–like Syndrome Without Bone Involvement

(2012) Rita João Guerreiro et al.   JAMA Neurology

Genetics: Finding risk factors

(2011) Michael Eisenstein   NATURE

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

(2011) Sergio T. Ferreira et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Oxidative Stress and β-Amyloid Protein in Alzheimer’s Disease

(2011) Zhiyou Cai et al.   NEUROMOLECULAR MEDICINE

Dual Induction of TREM2 and Tolerance-Related Transcript, Tmem176b, in Amyloid Transgenic Mice: Implications for Vaccine-Based Therapies for Alzheimer's Disease

(2010) Benoit Melchior et al.   ASN Neuro

The role of microglia in amyloid clearance from the AD brain

(2010) C. Y. Daniel Lee et al.   JOURNAL OF NEURAL TRANSMISSION

Alzheimer's failure raises questions about disease-modifying strategies

(2010) Andy Extance   NATURE REVIEWS DRUG DISCOVERY

Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain

(2010) Troy T. Rohn et al.   NEUROBIOLOGY OF DISEASE

The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?

(2010) Kerensa Broersen et al.   Alzheimers Research & Therapy

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice

(2008) Stefanie Frank et al.   GLIA

In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons

(2008) T. L. Spires-Jones et al.   JOURNAL OF NEUROSCIENCE