Article
Health Care Sciences & Services
Gizachew Beykaso, Tilahun Teklehaymanot, Mirutse Giday, Nega Berhe, Feleke Doyore, Dawit Hailu Alemayehu, Adane Mihret, Andargachew Mulu
Summary: This study revealed a high prevalence of viral transfusion-transmissible infections (TTIs) among blood donors in Hossana, Ethiopia, with an overall prevalence of 14.38%. HBV, HCV, and HIV had prevalence rates of 9.83%, 2.39%, and 4.31% respectively. Various factors were significantly associated with these viral infections. Effective donor selection and screening protocols are crucial to prevent transmission of these infectious pathogens.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2021)
Review
Biochemistry & Molecular Biology
Narges Hadjesfandiari, Mona Khorshidfar, Dana V. Devine
Summary: This review article examines the molecular differences impacting the quality of blood components, with a focus on factors affecting the quality of red blood cells and platelets, and emphasizes the importance of donor individual molecular and genetic profile in improving blood component quality.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Public, Environmental & Occupational Health
Raul Juarez-Vela, Manuel Quintana-Diaz, Antonio Rodriguez-Calvo, Jose Angel Santos-Sanchez, Maria Gero-Escapa, Elena Gallego-Curto, Pedro Jose Satustegui-Dorda, Juan Luis Sanchez-Gonzalez, Carlos Jerico, Regina Ruiz de Vinaspre-Hernandez, Guadalupe Gil-Fernandez, Jose Antonio Garcia-Erce
Summary: This study aimed to describe the factors associated with blood transfusion in polytraumatized patients admitted to the Intensive Care Unit (ICU). The results showed that transfused patients had higher severity scores and a higher incidence of kidney failure. Therefore, clinical practice guidelines regarding blood transfusion and its practices need to be considered.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Immunology
Juhye Roh, Jangwook Lee, Jinyoung Park, Hee Jung Kang, Young Kyung Lee, Han-Sung Kim, Yonggeun Cho
Summary: The COVID-19 outbreak led to a decreased utilization of blood products in hospitals due to social distancing measures and reduced blood donors. A retrospective study conducted in Korea found that there was a significant decrease in blood component transfusions and postoperative usage in 2020 compared to 2019. However, patient prognosis in terms of hospital stay and mortality did not show significant differences between the two years.
Review
Medicine, General & Internal
Mark Walsh, Ernest E. Moore, Hunter B. Moore, Scott Thomas, Hau C. Kwaan, Jacob Speybroeck, Mathew Marsee, Connor M. Bunch, John Stillson, Anthony V. Thomas, Annie Grisoli, John Aversa, Daniel Fulkerson, Stefani Vande Lune, Lucas Sjeklocha, Quincy K. Tran
Summary: This review examines the pathophysiology, geographic variation, and historical developments of fixed ratio versus whole blood resuscitation for hemorrhaging trauma patients. It introduces a physiologically driven and goal-directed alternative to guide blood component and factor concentrate administration to severely bleeding trauma patients, with a focus on major studies and upcoming comparative trials.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Immunology
Christos Gogos, Konstantinos Stamos, Nikolaos Tsanaxidis, Ioannis Styliadis, Ioanna Koniari, Sophia N. N. Kouni, Cesare de Gregorio, Nicholas G. G. Kounis
Summary: Kounis syndrome is a disease that affects the circulatory system and can result in spasms and blood clot formation. It can occur due to allergic or hypersensitivity reactions and involves the release of inflammatory mediators. The syndrome can affect various arteries, including the coronary arteries.
Review
Multidisciplinary Sciences
Jeanne Boudreaux
Summary: This article provides an overview of the current challenges and recommendations regarding transfusion management for thalassemia patients. It also discusses the components of blood safety and blood product modification for specific populations. The article describes adverse transfusion reactions and explores newer technologies to minimize the risk of transfusion-associated pathogens. Finally, the article briefly discusses research in blood storage and manufactured blood.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2023)
Article
Multidisciplinary Sciences
Jun Gong, Zhi Chen, Yi Zhang, Yi-yun Liu, Jun-cai Pu, Chun-yan Xiong, Si-wen Gui, Xiao-ling He, Hui-lai Wang, Xiao-gang Zhong
Summary: This study aimed to investigate the risk factors and develop a risk-factor model for postpartum hemorrhage (PPH) after cesarean delivery (CD). Through the application of multiple statistical models, 10 risk factors including placenta previa, gestational age, and prothrombin time were identified.
SCIENTIFIC REPORTS
(2022)
Review
Hematology
Jesus Rodriguez Corte, Cristina Candal-Pedreira, Alberto Ruano-Ravina, Monica Perez-Rios, Alejandro Rivero-de-Aguilar, Marisa Lopez Garcia, Leticia Hermida Porto, Leonor Varela-Lema
Summary: Home care is a healthcare alternative to hospitalisation, including procedures such as home blood transfusions. This study aimed to assess the safety and effectiveness of home blood transfusions, as well as patient acceptance and satisfaction. The results suggest that home blood transfusion is a feasible, safe, and well-accepted procedure. However, the limited quality of existing studies is a significant limitation in drawing definitive benefit-risk conclusions.
BRITISH JOURNAL OF HAEMATOLOGY
(2022)
Review
Multidisciplinary Sciences
Glenn A. Gaesser, Siddhartha S. Angadi
Summary: Aerobic fitness and physical activity play a crucial role in improving cardiometabolic risk markers and reducing mortality risk, more effectively than weight-loss programs. Weight loss does not necessarily reduce mortality risk, while intentional increases in physical activity can bring more benefits.
Article
Clinical Neurology
Charles C. Yu, Mohsin Fidai, Travis Washington, Stephen Bartol, Gregory Graziano
Summary: This study compared the effects of intravenous (IV) and oral (PO) tranexamic acid (TXA) on perioperative blood loss in patients undergoing thoracolumbar fusion. The results showed that there was no significant difference in the reduction of hemoglobin between the IV and PO groups, but the IV group had a higher transfusion rate and longer length of stay.
Article
Endocrinology & Metabolism
Olga M. Fajardo, Katherine F. Chaves, Zhiguo Zhao, Howard L. Curlin, Lara F. B. Harvey, Ted L. Anderson
Summary: This study aimed to investigate the association between preoperative hematocrit levels and the risk of blood transfusion during laparotomic and laparoscopic myomectomy, based on myoma burden and surgical route. The study found that incremental increases in hematocrit levels significantly decreased the risk of blood transfusion during myomectomy.
JOURNAL OF CLINICAL DENSITOMETRY
(2023)
Article
Multidisciplinary Sciences
Ziya Isiksacan, Angelo D'Alessandro, Susan M. Wolf, David H. McKenna, Shannon N. Tessier, Erdem Kucukal, A. Aslihan Gokaltun, Nishaka William, Rebecca D. Sandlin, John Bischof, Narla Mohandas, Michael P. Busch, Caglar Elbuken, Umut A. Gurkan, Mehmet Toner, Jason P. Acker, Martin L. Yarmush, O. Berk Usta
Summary: Transfusion of red blood cells is a valuable and widespread treatment in modern medicine. Current practices in blood transfusion overlook the variability in stored red blood cell quality. It is necessary to rethink transfusion medicine workflows and utilize novel technologies for assessing red blood cell quality.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Medicine, General & Internal
Valerie Y. Chock, Haresh Kirpalani, Edward F. Bell, Sylvia Tan, Susan R. Hintz, M. Bethany Ball, Emily Smith, Abhik Das, Yvonne C. Loggins, Beena G. Sood, Lina F. Chalak, Myra H. Wyckoff, Stephen D. Kicklighter, Kathleen A. Kennedy, Ravi M. Patel, Waldemar A. Carlo, Karen J. Johnson, Kristi L. Watterberg, Pablo J. Sanchez, Abbot R. Laptook, Ruth B. Seabrook, C. Michael Cotten, Toni Mancini, Gregory M. Sokol, Robin K. Ohls, Anna Maria Hibbs, Brenda B. Poindexter, Anne Marie Reynolds, Sara B. DeMauro, Sanjay Chawla, Mariana Baserga, Michele C. Walsh, Rosemary D. Higgins, Krisa P. Van Meurs
Summary: This study investigates the effects of red blood cell transfusion on cerebral and mesenteric tissue saturation in preterm infants and explores the association with degree of anemia and death or neurodevelopmental impairment. The results show an increase in tissue saturation after transfusion, and lower pretransfusion cerebral saturation may be associated with adverse outcomes.
Article
Gastroenterology & Hepatology
Marc G. Ghany, Anna S. F. Lok, Jules L. Dienstag, Stephen M. Feinstone, Jay H. Hoofnagle, T. Jake Liang, Leonard B. Seeff, David E. Cohen, Jorge A. Bezerra, Raymond T. Chung
Summary: The 2020 Nobel Prize in Medicine or Physiology was awarded to Drs. Harvey Alter, Michael Houghton, and Charles Rice for their groundbreaking contributions to the discovery and characterization of the hepatitis C virus (HCV). Their achievements have revolutionized the treatment of HCV and offer guidance for future researchers in the field. This tribute not only highlights the laureates' work, but also provides insights and inspiration for young investigators.