Article
Food Science & Technology
Natalia Zofia Maryniak, Ana Isabel Sancho, Egon Bech Hansen, Katrine Lindholm Bggh
Summary: Cow's milk allergy is the most prevalent type of food allergy among infants. There is a growing demand for more options for infant feeding, especially for the prevention and management of cow's milk allergy. Milk from other mammalian sources and proteins from plant sources have gained increased interest due to their potentially lower allergenicity.
Article
Nutrition & Dietetics
Yvan Vandenplas, Katerina Bajerova, Christophe Dupont, Philippe Eigenmann, Mikael Kuitunen, Rosan Meyer, Carmen Ribes-Koninckx, Silvia Salvatore, Raanan Shamir, Hania Szajewska
Summary: CoMiSS was developed 7 years ago as a tool to increase awareness among healthcare professionals about the possibility of infant symptoms being related to cow's milk. Based on extensive research, an updated CoMiSS with lowered required cutoff and adaptation for non-toilet trained children has been proposed. However, further studies are needed to evaluate its effectiveness and regional differences. It is important to note that CoMiSS is an awareness tool and not a diagnostic test.
Review
Nutrition & Dietetics
Katerina Bajerova, Silvia Salvatore, Christophe Dupont, Philippe Eigenmann, Mikael Kuitunen, Rosan Meyer, Carmen Ribes-Koninckx, Raanan Shamir, Hania Szajewska, Yvan Vandenplas
Summary: This review summarizes the current evidence on the Cow's Milk-related Symptom Score (CoMiSS), which is a clinical tool used to assess symptoms possibly related to cow's milk intake. It found that CoMiSS can be used to predict the response to a cow's milk-free diet in infants and diagnose cow's milk allergy in children.
Article
Chemistry, Analytical
Lucila Brusa, Mabel Tudino, Jonatan Schlotthauer, Mirna Sigrist
Summary: A method based on flow injection hydride generation atomic absorption spectrometry (FI-HGAAS) with an on-line pre-reduction of Se(VI) to Se(IV) was optimized and developed to determine phosphate-extractable Se. The method can eliminate interferences caused by organic matter and provide comparable results to ICP-MS.
Article
Chemistry, Applied
Xiaodan Wang, Huiquan Zhu, Wenyuan Zhang, Yumeng Zhang, Pu Zhao, Shuwen Zhang, Xiaoyang Pang, Jacques Vervoort, Jing Lu, Jiaping Lv
Summary: In this study, the triglyceride and fatty acid composition of different types of milk samples and infant formulae were analyzed using UPLC-ESI-MS and GC techniques. The results showed that the triglyceride and fatty acid composition varied significantly among different milk samples. Furthermore, the fatty acid profiles of human milk and yak milk were unique, which has implications for optimizing dairy product composition.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Article
Chemistry, Applied
Yan Liu, Yan Liu, Qian Liu, Junying Zhao, Weicang Qiao, Bin Liu, Baoyu Yang, Lijun Chen
Summary: Phospholipids play a crucial role in infant nutrition and cognitive development. It is believed that infant formula has lower levels of phospholipid species, content, and milk fat globule structural integrity compared to human milk. Through qualitative and quantitative analyses, it was found that the levels of phosphatidylethanolamine and sphingomyelin were significantly lower in infant formula than in human milk. Different types of infant formula showed variations in phospholipid species and content, with cow's milk-based formula having the highest number of species. The size, zeta potential, and amount of milk fat globules in infant formula were also lower than those in human milk. These findings can be used to improve the design of infant formula to better mimic human milk.
Article
Allergy
Tetsuhiro Sakihara, Kenta Otsuji, Yohei Arakaki, Kazuya Hamada, Shiro Sugiura, Komei Ito
Summary: Early discontinuation of cow's milk formula, particularly within the first month of life, is associated with the development of cow's milk allergy in infants who received cow's milk formula in the early days of life.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2022)
Article
Food Science & Technology
Natalia Zofia Maryniak, Mette Halkjaer Stage, Anne-Sofie Ravn Ballegaard, Ana Isabel Sancho, Egon Bech Hansen, Katrine Lindholm Bogh
Summary: Currently, there are no specific recommendations for using any particular infant formula to prevent cow's milk allergy. There is increasing interest in alternative infant formulas made from milk proteins from animals other than cows, but their ability to prevent cow's milk allergy has not been studied.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Chemistry, Analytical
Lindomar A. Portugal, Edwin Palacio, Rejane Frizzarin, Joao H. Santos Neto, Victor Cerda, Sergio L. C. Ferreira
Summary: This work proposes an automated strategy for the speciation of inorganic selenium in infusion tea samples. The system utilizes an MSFIA-CVG-AFS system and sodium tetrahydroborate for chemical vapor generation. The method involves an online prereduction step to convert selenium (VI) to selenium (IV) before determining the total selenium concentration. The chemical parameters were optimized using a fractional factorial design. The method exhibited low detection and quantification limits, with a linear range and good precision. This method was successfully applied to analyze inorganic selenium speciation in commercially purchased tea samples.
Article
Pediatrics
Brock A. Williams, Stephanie C. Erdle, Kelsey M. Cochrane, Kirstin Wingate, Kyla J. Hildebrand
Summary: Cow's milk allergy is a common food allergy in early childhood, affecting 2-5% of children worldwide. While most children eventually develop tolerance, selecting an appropriate alternative milk is crucial for their growth and development. The increasing variety of alternative milk products adds complexity for families and clinicians. This article aims to provide guidance to Canadian healthcare professionals on recommending the most suitable and nutritionally optimal alternatives for individuals with cow's milk allergy.
PAEDIATRICS & CHILD HEALTH
(2023)
Article
Nutrition & Dietetics
Narissara Suratannon, Panote Prapansilp, Athitaya Srinarongsook, Pornthep Tanpowpong, Pantipa Chatchatee, Krit Pongpirul
Summary: This study assessed the cost-effectiveness of different therapeutic infant formulas for managing cow's milk protein allergy (CMPA) in Thailand, which may reflect situations in developing countries throughout Asia. The results showed that extensively hydrolyzed casein formula with added probiotic Lacticaseibacillus rhamnosus (EHCF+LGG) was the most cost-effective strategy for managing non-breastfed infants with CMPA.
FRONTIERS IN NUTRITION
(2023)
Article
Allergy
Lamia Dahdah, Mieke Roelofs, Karen Knipping, Esther de Vries, Anneke Rijnierse, Johan Garssen, Paul L. P. Brand, Alessandro Fiocchi
Summary: This study evaluated the hypoallergenicity, growth, and gastrointestinal tolerability of a new extensively hydrolyzed whey-protein formula in children with cow's milk allergy. The results showed that all subjects tolerated the formula, and it was associated with normal growth and gastrointestinal tolerability.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Nutrition & Dietetics
Xiaoli Zhao, Suzan Thijssen, Hongbing Chen, Johan Garssen, Leon M. J. Knippels, Astrid Hogenkamp
Summary: Dietary selenium supplementation may modulate allergic responses to whey by decreasing specific antibody responses and mMCP-1 release.
Article
Allergy
Tetsuhiro Sakihara, Kenta Otsuji, Yohei Arakaki, Kazuya Hamada, Shiro Sugiura, Komei Ito
Summary: The study findings indicate that early introduction of cow's milk formula can effectively prevent the development of cow's milk allergy. This strategy can be implemented without competing with breastfeeding.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2021)
Article
Chemistry, Analytical
Michelle Buoso, Beatrice Campanella, Massimo Onor, Emanuela Pitzalis, Alessandro D'Ulivo
Summary: The use of BH intermediates as derivatization reagents significantly improves the tolerance to interference from transition metal ions in the generation of SbH3 and BiH3, and shows high tolerance in a wide range of acidity. The method has been successfully applied to the determination of Sb and Bi in complex samples, providing further understanding of the chemical behavior of borohydrides.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)
Article
Chemistry, Analytical
Moises Knochen, Juan Carlos Rodriguez-Silva, Javier Silva-Silva
Article
Food Science & Technology
Fiorella Iaquinta, Florencia Tissot, Lucimar Lopes Fialho, Joaquim A. Nobrega, Mariela Piston, Ignacio Machado
Summary: An optimized method using tetramethylammonium hydroxide for alkaline sample treatment was validated for the determination of Cu, Mo, and Zn in beef samples from Uruguay. The method involved multivariate experiments, flame atomic absorption spectrometry for Cu and Zn, and electrothermal atomic absorption spectrometry for Mo. The results showed statistical equivalence to certified values and total acid digestion, with analytical precision below 8%.
FOOD ANALYTICAL METHODS
(2021)
Article
Biochemistry & Molecular Biology
Javier Silva, Mariela Piston
Summary: An online preconcentration system was developed to simultaneously determine copper and manganese in water samples, using a sisal fiber-packed minicolumn and MIP OES. The optimal conditions for sample preparation were determined, leading to detection limits of 3.7 and 9.0 μg L-1 for Cu and Mn, respectively. The system showed a high enrichment factor and was synchronized with MIP OES for rapid and accurate analysis of samples.
Article
Chemistry, Analytical
Mariela Piston, Ignacio Machado, Esteban Rodriguez-Arce, Isabel Dol
Summary: A green analytical method was developed for determining Cu and Zn in rice samples, using ozone-assisted extraction (OAE) in diluted acid media. The method was found to be simple, economical, and yielded results comparable to traditional methods.
JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY
(2021)
Article
Food Science & Technology
Fiorella Iaquinta, Lucimar Lopes Fialho, Joaquim A. Nobrega, Mariela Piston, Ignacio Machado
Summary: An analytical method for determination of Cd, Pb and Se in beef using ICP-MS was developed and validated in this study. Results showed that levels of Cd and Pb in beef from Uruguay were below international regulations, while Se content was relatively high, contributing to the daily intake of this essential element.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2021)
Article
Chemistry, Analytical
Alicia Mollo, Alexandra Sixto, Florencia Cora Jofre, Mariela Piston, Marianela Savio
Summary: A hydride generation nitrogen microwave induced plasma optical emission spectrometry (HG-MIP OES) system was developed for lead determination using specific additives and reductants in acidic medium. The study optimized operating conditions and conducted a detailed investigation of nitrogen plasma response. The method showed comparable performance to other atomic spectrometry techniques in terms of limits of detection and quantification.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Chemistry, Analytical
Pablo Gonzalez, Nicolas Perez, Moises Knochen
Summary: This paper presents the design and construction of an automated analyzer for on-site determination of nutrients in surface waters. The analyzer utilizes a pulsed flow analysis system with solenoid micropumps and employs photometric detection based on LEDs and photodiodes. It can detect orthophosphate, nitrite, and nitrate. The analyzer performs a complete analysis cycle every 6 hours and delivers the results to the end user via text messages.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Fiorella Iaquinta, Jessica Santander, Mariela Piston, Ignacio Machado
Summary: Four methods for efficient extraction of copper from bovine and ovine liver were optimized and validated in this study. The selected methods, assisted by an ultrasonic probe, demonstrated higher efficiency and faster extraction compared to other methods. The accuracy and precision of these methods were verified through the analysis of certified reference materials and the evaluation of microwave-assisted extraction. The results obtained from Uruguayan animal samples agreed with previous findings from different countries. The proposed methods provide simple alternatives for food surveillance and animal status monitoring, aligning with the principles of Green Chemistry. Furthermore, the study explored the effect of ultrasound on the particle size distribution of biological tissues in different media and compared the ultrasound-assisted extraction with magnetic stirring.
BRAZILIAN JOURNAL OF ANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Karolina Soca Rosas, Fernando Igoa, Jorge Castiglioni, Leopoldo Suescun, Carlos Kremer, Moises Knochen, Julia Torres
Summary: This study presents a low-cost in-situ luminescence measuring experimental array for solid-state sensing of vapors. The experimental array allows repeated activation and guest entrance, providing accurate and reproducible in-situ data. The results show that the presented method is simple, robust, and trustworthy, with minimal light-induced degradation of the tested materials.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Spectroscopy
P. Pizzorno, L. Falchi, N. Manay, M. Piston, V. Buhl
Summary: This analytical note presents a simple and economic method for quantifying arsenic species in urine, which is helpful for assessing the health risk of arsenic exposure through drinking water. The method's accuracy and precision are within acceptable ranges, with limits of detection and quantification of 1.8 and 5.4 μg/L, respectively. It can be considered as a viable alternative to expensive techniques for biomonitoring studies.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Article
Multidisciplinary Sciences
Javier Silva, Valery Buhl, Fiorella Iaquinta, Mariela Piston
Summary: Green Analytical Chemistry metrics include various criteria such as reagent amounts, toxicity, energy consumption, and waste generation. The Analytical Greenness metric (AGREE) and its variant for sample preparation (AGREEprep) cover different aspects related to environmental sustainability. White Analytical Chemistry considers environmental aspects as well as analytical and practical aspects in a holistic manner.
Article
Agronomy
A. Sixto, A. Mollo, F. Ibanez, M. Piston
Summary: Vegetables, especially potatoes and sweet potatoes, are important sources of macro and micronutrients, but they can be contaminated with inorganic contaminants, causing concerns for food safety. This study focused on the presence of arsenic, cadmium, and lead in peeled and whole potatoes and sweet potatoes. The content of these contaminants was generally below the maximum allowed levels, but cadmium was detected in whole sweet potatoes and lead was present in most of the sweet potato samples analyzed. This highlights the importance of analyzing the whole vegetable and having methods available for assessing the risk of consuming these contaminants.
AGROCIENCIA URUGUAY
(2023)
Article
Multidisciplinary Sciences
Maria Cecilia Geisenblosen, Pedro Oyhantcabal, Mariela Piston
Summary: An analytical method using MP-AES was developed for sample preparation and determination of major elements in igneous rocks, providing a reliable alternative to traditional analytical procedures. This method was successfully applied to chemical classification of rocks from Uruguay.
Article
Chemistry, Multidisciplinary
Monica Pereira, Florencia Tissot, Ricardo Faccio, Facundo Ibanez, Mariela Piston
Summary: The study introduced a simple and economical UAE method for determining Cd and Pb levels in fruits and vegetables, with lower detection limits compared to MAE. Results from testing vegetable samples indicated that both UAE and MAE methods provided comparable results that met the maximum allowed concentration standards set by the WHO. Confocal optical images of the treated SRM revealed the effects of ultrasonic treatment on plant tissue, showing desaturation, erosion, and abrasion increasing with longer sonication times. The UAE method was found to meet and exceed the requirements of a standard method for ensuring food safety.
RESULTS IN CHEMISTRY
(2021)
Article
Chemistry, Analytical
Gang Qu, Yuxin Zhao, Qiaoli Zhang, Jina Wu, Xiaosen Li, Yang Yang, Shilei Liu
Summary: In this study, magnetic mesoporous materials combined with real-time in situ mass spectrometry were used for the high-throughput detection of hydrolyzed products of organophosphorus nerve agents. The method showed good linearity, low limits of detection and quantification, and high extraction recoveries. The magnetic preparation method used was quick, cost-effective, rugged, and safe. The results demonstrated the potential of this method for rapid and efficient determination of the target analytes in environmental samples.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Anna Hildebrand, Mariam Merchant, Danny O'Hare
Summary: Substandard and falsified artemisinin derivatives in antimalarials have caused significant deaths and economic losses. This study evaluates the feasibility of voltammetric methods for identifying and quantifying artemether. The findings suggest that electrochemical analysis shows promise as a method for artemether identification and quantification.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Marx Osorio Araujo Pereira, Alvaro Ferreira Junior, Edson Silvio Batista Rodrigues, Helena Mulser, Giovanna Nascimento de Mello e Silva, Wallans Torres Pio dos Santos, Eric de Souza Gil
Summary: Brazilian spotted fever (BSF) is a serious and rapidly evolving disease. A new impedimetric immunosensor was developed for rapid diagnosis by measuring specific antibodies in plasma. The sensor demonstrated selectivity and accuracy, and has potential for important applications in diagnostic testing.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Kathrin Schilling, Ronald A. Glabonjat, Olgica Balac, Marta Galvez-Fernandez, Arce Domingo-Relloso, Vesna Slavkovich, Jeff Goldsmith, Miranda R. Jones, Tiffany R. Sanchez, Ana Navas-Acien
Summary: Analysis of trace elements in urine is an important tool for assessing exposures, diagnosing nutritional status, and guiding public health and healthcare intervention. This study provides a sensitive method for analyzing 18 elements in urine samples, using only 100 μL. The results show good accuracy and sensitivity of the method.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Mengya Li, Shijie Liu, Shiliang Guo, Dong Liang, Miaoyun Li, Yaodi Zhu, Lijun Zhao, Jong-Hoon Lee, Gaiming Zhao, Yangyang Ma, Yanxia Liu
Summary: In this study, a magnetic flow device was developed to purify spores in a culture medium system. The device used magnetic nanoparticles to absorb vegetative cells, separating them from the spores. The achieved purity of the collected spores was over 95%. The study also demonstrated a rapid quantitative detection method using Raman spectroscopy.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Wanqiong Liu, Zixuan Wu, Jianwei Peng, Zebin Xu, Yong Liang
Summary: Metal-organic frameworks (MOFs) are effective carriers for molecular imprinting, but their poor dispersibility in aqueous solution is a significant drawback. In this study, we have applied amphiphilic block copolymers and molecularly imprinted technology on MOFs to improve the hydrophilicity of molecularly imprinted fluorescent materials.
ANALYTICAL METHODS
(2024)