Antitumor Effects of Vitamin D Analogs on Hamster and Mouse Melanoma Cell Lines in Relation to Melanin Pigmentation

Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways

(2014) Andrzej Slominski et al.   Anti-Cancer Agents in Medicinal Chemistry

The role of melanogenesis in regulation of melanoma behavior: Melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathways

(2014) A. Slominski et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D

(2014) Andrzej T. Slominski et al.   FASEB JOURNAL

Melanoma Resistance: A Bright Future for Academicians and a Challenge for Patient Advocates

(2014) Andrzej T. Slominski et al.   MAYO CLINIC PROCEEDINGS

In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland

(2014) Andrzej T. Slominski et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Vitamin D analogs combined with 5-fluorouracil in human HT-29 colon cancer treatment

(2014) MAGDALENA MILCZAREK et al.   ONCOLOGY REPORTS

The melanoma revolution: From UV carcinogenesis to a new era in therapeutics

(2014) J. A. Lo et al.   SCIENCE

Interaction of vitamin D with membrane-based signaling pathways

(2014) María Jesús Larriba et al.   Frontiers in Physiology

Melanogenesis affects overall and disease-free survival in patients with stage III and IV melanoma

(2013) Anna A. Brożyna et al.   HUMAN PATHOLOGY

Steroidogenesis in the skin: Implications for local immune functions

(2013) Andrzej Slominski et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions

(2013) Andrzej T. Slominski et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Extrarenal expression of the 25-hydroxyvitamin D-1-hydroxylase

(2012) J.S. Adams et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

New vitamin D analogs as potential therapeutics in melanoma

(2012) Paulina Szyszka et al.   Expert Review of Anticancer Therapy

In vivo evidence for a novel pathway of vitamin D3 metabolism initiated by P450scc and modified by CYP27B1

(2012) Andrzej T. Slominski et al.   FASEB JOURNAL

Expression of the vitamin D–activating enzyme 1α-hydroxylase (CYP27B1) decreases during melanoma progression

(2012) Anna A. Brożyna et al.   HUMAN PATHOLOGY

Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength

(2012) Tae-Kang Kim et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Role of the Vitamin D Receptor and ERp57 in Photoprotection by 1α,25-Dihydroxyvitamin D3

(2012) Vanessa B. Sequeira et al.   MOLECULAR ENDOCRINOLOGY

25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D

(2011) Glenville Jones et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Vitamin D and cancer: a review of molecular mechanisms

(2011) James C. Fleet et al.   BIOCHEMICAL JOURNAL

High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives

(2011) Z Janjetovic et al.   BRITISH JOURNAL OF CANCER

Expression of vitamin D receptor decreases during progression of pigmented skin lesions

(2011) Anna A. Brożyna et al.   HUMAN PATHOLOGY

Camptothecin-induced death of amelanotic and melanotic melanoma cells in different phases of cell cycle

(2011) M. CICHOREK   NEOPLASMA

L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functions

(2011) Andrzej Slominski et al.   Pigment Cell & Melanoma Research

Products of Vitamin D3 or 7-Dehydrocholesterol Metabolism by Cytochrome P450scc Show Anti-Leukemia Effects, Having Low or Absent Calcemic Activity

(2010) Andrzej T. Slominski et al.   PLoS One

Synthesis and photochemical transformation of 3β,21-dihydroxypregna-5,7-dien-20-one to novel secosteroids that show anti-melanoma activity

(2010) Michal A. Zmijewski et al.   STEROIDS

Crystal Structure of CYP24A1, a Mitochondrial Cytochrome P450 Involved in Vitamin D Metabolism

(2009) Andrew J. Annalora et al.   JOURNAL OF MOLECULAR BIOLOGY

20-Hydroxycholecalciferol, Product of Vitamin D3 Hydroxylation by P450scc, Decreases NF-κB Activity by Increasing IκBα Levels in Human Keratinocytes

(2009) Zorica Janjetovic et al.   PLoS One

Metabolism of Vitamin D2 to 17,20,24-Trihydroxyvitamin D2 by Cytochrome P450scc (CYP11A1)

(2008) M. N. Nguyen et al.   DRUG METABOLISM AND DISPOSITION

Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc

(2008) Robert C. Tuckey et al.   FEBS Journal

Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy

(2008) Anna A. Brożyna et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibitors of melanogenesis increase toxicity of cyclophosphamide and lymphocytes against melanoma cells

(2008) Andrzej Slominski et al.   INTERNATIONAL JOURNAL OF CANCER

20-Hydroxyvitamin D3, a Product of Vitamin D3 Hydroxylation by Cytochrome P450scc, Stimulates Keratinocyte Differentiation

(2008) Blazej Zbytek et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives

(2008) Michal A. Zmijewski et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3β, 17α, 20-triol and their bioactivity in melanoma cells

(2008) Michal A. Zmijewski et al.   STEROIDS