Article
Electrochemistry
Janis S. Borchers, Claire R. Campbell, Savanah B. Van Scoy, Morgan J. Clark, Robbyn K. Anand
Summary: An array of bipolar electrodes can be controlled by a single pair of driving electrodes, allowing for multiplexed analysis of multiple biomarkers or cells simultaneously. By utilizing signal amplification through redox cycling, the detection limit decreases by an order of magnitude, enabling multiplexed or spatially resolved sensing at the point of need.
Article
Chemistry, Analytical
Nurul Asyikeen Ab Mutalib, Yi Deng, An-Ju Hsueh, Koki Kariya, Toshiaki Kurihara, Hiroaki Suzuki
Summary: The research controlled the interfacial potential difference on bipolar electrodes by placing Ag/AgCl, coupling oxygen reduction with electrochemiluminescence (ECL) reaction. In an open bipolar system, ECL intensity depended on Ag/AgCl location and Cl- ion concentration. The study also demonstrated the effectiveness of Ag/AgCl in adjusting sensitivity to analytes like H2O2 and glucose in a closed bipolar system.
Article
Chemistry, Multidisciplinary
Xin He, Jue Wu, Zhuoying Zhu, Haodong Liu, Ning Li, Dong Zhou, Xu Hou, Jun Wang, Haowei Zhang, Dominic Bresser, Yanbao Fu, Matthew J. Crafton, Bryan D. McCloskey, Yan Chen, Ke An, Ping Liu, Anubhav Jain, Jie Li, Wanli Yang, Yong Yang, Martin Winter, Robert Kostecki
Summary: This study provides a comparative study of transition metals and oxygen redox activities in Li-rich materials operated at different current rates. It reveals a reaction gradient of lattice oxygen redox reactions and a dynamic compatibility between the oxidation processes of lattice oxygen and transition metals. The study also proposes a detailed mechanism of structural distortion and the role of oxygen vacancies in Li+ diffusion.
ENERGY & ENVIRONMENTAL SCIENCE
(2022)
Review
Chemistry, Multidisciplinary
Shan-Shan Li, Ai-Jun Wang, Pei-Xin Yuan, Li-Ping Mei, Lu Zhang, Jiu-Ju Feng
Summary: This article summarizes the activity modulation of heterometallic nanomaterials (HMNMs) and their recent applications in sensing, imaging, and therapy. It also provides an outlook on their future directions.
Article
Multidisciplinary Sciences
Joshua Zonca, Anna Folso, Alessandra Sciutti
Summary: Research suggests that within a social group, individuals are influenced by indirect reciprocity, and tend to rely more on the judgments of those who support their opinions, rather than considering the reliability of these judgments. This effect diminishes when individuals no longer expect future interactions with these individuals, indicating the emergence of downstream effects of indirect reciprocity mechanisms.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Multidisciplinary
Gang Liu, Yifa Chen, Yulu Chen, Yanqi Shi, Meiyu Zhang, Guodong Shen, Pengfei Qi, Jikun Li, Delong Ma, Fei Yu, Xianqiang Huang
Summary: This study explores the conversion of cheap organic raw materials into valuable chemicals for industrial rubber production through indirect electrocatalysis. By fabricating di-copper-substituted phosphotungstate-based foams, the researchers achieved successful synthesis of sulfenamides and disulfides. The optimal catalyst PW10Cu2@CMC showed excellent electrocatalytic performance and enabled scale-up production, with the resulting products serving as high-performance rubber vulcanization accelerators.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Gang Liu, Yifa Chen, Yulu Chen, Yanqi Shi, Meiyu Zhang, Guodong Shen, Pengfei Qi, Jikun Li, Delong Ma, Fei Yu, Xianqiang Huang
Summary: This study presents a promising strategy of indirect electrocatalytic conversion for the production of value-added chemicals for industrial rubber from cheap organic raw materials. A series of di-copper-substituted phosphotungstate-based foams were fabricated and successfully applied in the synthesis of sulfenamides and disulfides. The optimal catalyst exhibited excellent performance in producing H2 and constructing S-N/S-S bonds.
ADVANCED MATERIALS
(2023)
Article
Medicine, Research & Experimental
Liping Chen, Guihui Qin, Yuhong Liu, Moxin Li, Yue Li, Lun-Zhang Guo, Lidong Du, Weiming Zheng, Pei-Chun Wu, Yueh-Hsun Chuang, Xiaoyan Wang, Tzung-Dau Wang, Ja-An Annie Ho, Tzu-Ming Liu
Summary: The study identifies distinguishable features of prediabetic adipose tissues through metabolic imaging, providing a potential diagnostic method for prediabetes. In prediabetic adipose tissues, only adipocytes exhibit a low redox ratio of metabolic fluorescence and high free NAD(P)H fraction, which could be a risk indicator of prediabetic insulin resistance.
Review
Chemistry, Physical
Todd H. Lewis, Bo Zhang
Summary: Closed-bipolar electrochemical imaging (c-BPI) solves the tradeoff problem between optical response, spatial resolution, and photon efficiency in electrochemical heterogeneity imaging by coupling optical and electrochemical signals. Considering the potential for sensing ultra-transient events, we focus on fluorescence as a useful tool in c-BPI and examine the advantages and challenges of electrofluorogenic reporting strategies, providing solutions through direct and indirect approaches for electrochemical fluorescence imaging in closed-bipolar sensing systems.
CURRENT OPINION IN ELECTROCHEMISTRY
(2023)
Article
Chemistry, Physical
Hyunhong Kim, Hyeonjung Kim, Su Hwan Kim, Jong Mok Park, Yu Jin Jung, Sang Kyu Kwak, Jongnam Park
Summary: The research demonstrates that amine-mediated redox control of a catechol system can achieve conformal nanocoatings, helping reduce cohesion and enhance adhesion. These coatings exhibit very low roughness and thickness on flat substrates, and can be applied in various fields requiring nanoscale coating layers.
CHEMISTRY OF MATERIALS
(2021)
Review
Chemistry, Analytical
Ze-Jun Li, Cai-Yun Wang, Liang Xu, Zhen-Yu Zhang, Ying-Hao Tang, Tian-Yi Qin, Ya-Long Wang
Summary: Leucine aminopeptidase (LAP) is an important protease that hydrolyzes Leucine residues. It is involved in various physiological processes in the human body and abnormal levels of LAP are associated with diseases like cancer and drug-induced liver injury. Therefore, developing efficient technology to monitor LAP levels is crucial. This summary focuses on the organic small molecule fluorescence/chemiluminescence probes used for LAP detection in recent years, which have potential applications in cancer imaging, drug-induced liver injury, and bacterial detection.
Article
Nanoscience & Nanotechnology
Min A. Kim, Dan C. Sorescu, Shigeru Amemiya, Kenneth D. Jordan, Haitao Liu
Summary: This study reports the impact of mechanically applied elastic strain on the hydrogen evolution reaction (HER) activity of graphene under acidic conditions. A tensile strain of 0.2% on a graphene electrode leads to a 1-3% increase in the HER current. Theoretical calculations using a periodic graphene slab model predict an increase in the adsorption energy of the H atom with increasing tensile strain, which is consistent with the experimental observations of enhanced HER current density.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Chang Liu, Xiaowei Chi, Cheng Yang, Yu Liu
Summary: This study proposes a unique approach to increase the voltages of aqueous zinc batteries by using a tri-functional metallic bipolar electrode. The bipolar electrode not only participates in redox reactions but also functions as an electrical highway for charge transport. It can also replace expensive ion selective membrane to separate electrolytes with different pH, leading to high voltages of aqueous zinc batteries.
ENERGY & ENVIRONMENTAL MATERIALS
(2023)
Article
Cell Biology
Ester Mazepa, Ana Luiza Dorigan de Matos Furlanetto, Hulyana Brum, Lia Sumie Nakao, Pierina Alexandra Martinez, Silvia Maria Suter Correia Cadena, Maria Eliane Merlin Rocha, Elizabeth Sousa Cunha, Glaucia Regina Martinez
Summary: In this study, we found that the activity of secreted QSOX is higher in melanoma cells and is further increased after stimulation of melanogenesis. Depleting intracellular GSH disrupts the redox homeostasis and increases oxidative stress in the cells. These findings suggest that QSOX and GSH play important roles in melanogenesis and cellular adaptive response.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2023)
Article
Chemistry, Analytical
Meng Li, Haoran Li, Hua Su, Wei Wang
Summary: The study combines principles of surface plasmon resonance imaging (SPRi) and a closed bipolar electrode (CBPE) to image electron transfer at a semiconductor-metal interface. By utilizing a two-cell configuration, electron transfer at the interface can be visualized and the process can be optically monitored in real time using SPR signals.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Tatjana Safarik, Aleksandar Karajic, Stephane Reculusa, Philip N. Bartlett, Nicolas Mano, Alexander Kuhn
Summary: This study reports the electrochemical elaboration and characterization of a 3D coaxial macroporous twin-electrode, which is obtained by a low-cost bottom-up approach using nanoengineered highly organized porous material. The resulting electrode architecture allows for signal amplification in electroanalytical measurements and has potential applications in various (bio)electroanalytical fields.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Anne de Poulpiquet, Neso Sojic, Laurent Bouffier, Alexander Kuhn, Dodzi Zigah
Summary: Electrochemistry is an important topic taught in undergraduate chemistry programs, but students often find it difficult due to the combination of various physical concepts involved. Bipolar electrochemistry is of special interest for teaching purposes, as it has a simple setup and allows for the tuning of electrochemical reactions through manipulating the electric field. Basic experiments using a commercially available light emitting diode (LED) as a bipolar electrode are introduced here, illustrating the key parameters driving electrochemical reactions and providing an eye-catching introduction to general electrochemistry.
JOURNAL OF CHEMICAL EDUCATION
(2023)
Article
Chemistry, Physical
Ritu Toor, Lysandre Hourdin, Sharvina Shanmugathasan, Pauline Lefrancois, Stephane Arbault, Veronique Lapeyre, Laurent Bouffier, Jean-Paul Douliez, Valerie Ravaine, Adeline Perro
Summary: The design of enzymatic droplet-sized reactors is an important challenge with potential applications in medical diagnostics, water purification, bioengineering, and the food industry. This study demonstrates the construction of enzymatic reactors using coacervates formed by ampholyte polymer chains stabilized with agar. The coacervates can sequester and preserve the catalytic activity of enzymes such as glucose oxidase and catalase. The study investigates the enzymatic cascade reaction within the coacervates and provides new insights into the impact of proximity and confinement on enzymatic activity.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
Gerardo Salinas, Cara Lozon, Alexander Kuhn
Summary: The theory of electromagnetism has played a crucial role in understanding physicochemical phenomena and remains relevant in various scientific fields. Magnetohydrodynamics (MHD), which uses electromagnetism to induce physical flux in a fluid containing ions, has been explored in electrochemistry to create chiral structures and overcome mass transport limitations. This review discusses the principles of MHD convection and recent unconventional approaches to integrating magnetic fields in electrochemical systems.
CURRENT OPINION IN ELECTROCHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Paul Chassagne, Patrick Garrigue, Alexander Kuhn
Summary: Asymmetric modification of particles is a significant challenge in surface chemistry. This approach has potential applications in various fields including materials science, catalysis, self-assembly and drug delivery. However, there is currently a lack of straightforward synthesis methods for complex objects of this nature. In this study, bipolar electrochemistry is utilized to modify particles with different metal patches at predefined positions, allowing for highly controlled modifications in solution.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Supattra Somsri, Banyong Suwankaisorn, Krissanapat Yomthong, Wanmai Srisuwanno, Sorasak Klinyod, Alexander Kuhn, Chularat Wattanakit
Summary: Enantioselective catalysis is crucial in modern chemistry and pharmaceutical science. In this study, nanostructured metal layers imprinted with chiral information were developed as catalysts for the asymmetric synthesis of pharmaceutical compounds. The designed materials were successfully used as catalytically active stationary phases for continuous asymmetric flow synthesis. This work demonstrates the potential of producing real chiral pharmaceuticals at nanostructured metal surfaces.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Physical
Gerardo Salinas, Alexander Kuhn, Serena Arnaboldi
Summary: In this study, a simple and original self-propelled bimetallic Janus rotor was designed. The rotor is powered by the combination of a spontaneous electric and ionic current, generated by two coupled redox reactions, and a magnetic field placed orthogonal to the device surface. This design produces a magnetohydrodynamic vortex at each extremity of the rotor arm, generating an overall driving force for propulsion. The direction of the self-polarized object can be controlled by the direction of the electric current or the orientation of the external magnetic field, resulting in predictable motion.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Electrochemistry
Gerardo Salinas, Laurent Bouffier, Neso Sojic, Alexander Kuhn
Summary: Thermodynamics is an intriguing aspect of physical chemistry that is involved in various natural phenomena. The spontaneity of a chemical reaction is directly related to fundamental thermodynamic parameters such as the Gibbs free energy change. The visualization of electromotive force allows students to understand the underlying concepts of spontaneity in coupled reactions. This study introduces the thermodynamic concept of spontaneity to undergraduate students using the concepts of endogenous and exogenous bipolar electrochemistry. By encoding the chemical information of two coupled reactions through the light emission of a light-emitting diode used as a bipolar electrode, the thermodynamic information of the involved redox reactions can be directly read out.
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Marcin Dabrowski, Stephane Reculusa, Damien Thuau, Cedric Ayela, Alexander Kuhn
Summary: This article presents a novel and cost-effective strategy for enhancing the sensing performance of cantilever-shaped, mass-sensitive sensors. The strategy involves introducing macroporosity in the recognition unit. The sensors developed using this strategy are successfully used for air humidity monitoring and chemical sensing.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Chemistry, Physical
Gerardo Salinas, Serena Arnaboldi, Patrick Garrigue, Giorgia Bonetti, Roberto Cirilli, Tiziana Benincori, Alexander Kuhn
Summary: Chemistry on-the-fly is a concept that has been extensively studied in recent years for its potential in recognizing, quantifying, and converting chemical species in solution. This study proposes a promising approach for asymmetric synthesis using a combination of a magnetic field-enhanced self-electrophoretic propulsion mechanism and enantioselective redox chemistry. By employing Janus swimmers as redox-active elements, the conversion of a prochiral molecule into a specific enantiomer with high enantiomeric excess can be achieved spontaneously while the swimmers move. The magnetic field-enhanced self-mixing of the swimmers improves the reaction yield and conversion rate through the formation of local magnetohydrodynamic vortices.
FARADAY DISCUSSIONS
(2023)
Article
Chemistry, Multidisciplinary
Thitapond Nulek, Serena Arnaboldi, Gerardo Salinas, Giorgia Bonetti, Roberto Cirilli, Tiziana Benincori, Chularat Wattanakit, Adrian E. E. Flood, Alexander Kuhn
Summary: Preferential crystallization induced by chiral surfaces is used to isolate enantiopure antipodes. In this study, inherently chiral oligomers are used for enantioselective crystallization of asparagine and glutamic acid, which have no structural correlation with the template. This approach shows versatility and has potential applications in the resolution of pharmaceutical compounds.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Sabrina Bichon, Priscilla Staigre, Sebastien Gounel, Tatjana Safarik, Cristina Carucci, Alexander Kuhn, Nicolas Mano
Summary: The researchers have developed a strategy to stabilize and maintain enzyme activity in mixed-solvent systems by using engineered enzymes and tuned osmium-based redox polymers. They have validated this approach and demonstrated the wide applicability of the electrode in various organic solvents.
JOURNAL OF CATALYSIS
(2023)
Article
Chemistry, Physical
Yuhan Huang, David Talaga, Patrick Garrigue, Gerardo Salinas, Gary S. Cooney, Stephane Reculusa, Alexander Kuhn, Laurent Bouffier, Sebastien Bonhommeau
Summary: Potentiostatic electrodeposition was used to manufacture gold-coated AFM tips for TERS applications. The growth of the gold film was initiated by instantaneous nucleation on the doped-silicon tip surface. This cost-effective method allowed the production of robust AFM-TERS probes with localized surface plasmon resonances, achieving a yield of 53%. These probes enable TERS mapping of graphene oxide flakes and carbon nanotubes with lateral resolution below 20 nm, independent of the curvature radius of the metallized tip apex.
CHEMICAL PHYSICS LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Miaoxia Liu, Gerardo Salinas, Jing Yu, Antoine Cornet, Haidong Li, Alexander Kuhn, Neso Sojic
Summary: Multimodal imaging is a powerful approach that integrates multiple optical modalities in a single device, with potential applications in various fields. In this study, we developed wireless multimodal light-emitting chemical systems by coupling two light sources based on different physical principles. The results provide a novel alternative for designing autonomous hybrid systems with multimodal and multicolor optical readouts for complex bio-chemical systems.
