Article
Chemistry, Analytical
Chungen Qian, Yujin Xiao, Jie Wang, Yiwei Li, Shunji Li, Bo Wei, Wei Du, Xiaojun Feng, Peng Chen, Bi-Feng Liu
Summary: Exosomes, along with their associated proteins and nucleic acids, are recognized as biomarkers for tumor diagnosis and prognosis. Detecting exosomes is challenging due to their small size and low concentration. A low-cost, rapid, and portable agarose-based microfluidic chip for exosome concentration and in situ exosomal microRNA detection was developed, providing a new avenue for early cancer detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Naresh Mandal, Victor Pakira, Nirmalya Samanta, Naren Das, Suman Chakraborty, Bidhan Pramanick, Chirasree RoyChaudhuri
Summary: The study introduces an affordable label free graphene FET sensor for PSA detection, integrated with a microfluidic platform, achieving high selectivity and sensitivity.
Article
Biophysics
Yongfeng Zhu, Xia Tong, Qisheng Wei, Guihan Cai, Yuanxin Cao, Chaoying Tong, Shuyun Shi, Fang Wang
Summary: A novel platform for multiplex enzyme detection was developed based on 3D origami microfluidic paper-based device, allowing simultaneous detection of two enzymes' activities without pretreatment procedures. The platform exhibited excellent selectivity, good precision, favorable linear range, and high accuracy, successfully detecting alkaline phosphatase and butyrylcholinesterase in human serum samples.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Food Science & Technology
Xuan Weng, Cheng Zhang, Hai Jiang
Summary: Rapid and accurate detection of foodborne pathogens is crucial for preventing outbreaks, and microfluidic nanobiosensors show promise in achieving this by reducing assay time, enhancing sensitivity, and improving accuracy.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Li Huang, Enben Su, Yuan Liu, Nongyue He, Yan Deng, Lian Jin, Zhu Chen, Song Li
Summary: The developed microfluidic chip in this study aims to improve the accuracy of the chromatography system, with significant improvements in detection sensitivity and determination correlation. By enhancing the mixing between the sample and microspheres, the coefficient of variation of the traditional strip can be effectively increased.
CHINESE CHEMICAL LETTERS
(2021)
Review
Chemistry, Analytical
Naseem Abbas, Sehyeon Song, Mi-Sook Chang, Myung-Suk Chun
Summary: Bacterial infections, specifically Escherichia coli (E. coli) O157:H7, pose a serious threat to public health and require rapid and accurate detection methods. Traditional approaches like PCR and ELISA have limitations in terms of time and cost. Microfluidic platforms based on SPR, electrochemical sensing, and RCA offer promising alternatives for the detection of pathogens, providing rapid and portable point-of-care diagnostic tools.
Review
Medicine, Research & Experimental
Trey W. Pittman, Daniel Balazs Decsi, Chamindie Punyadeera, Charles S. Henry
Summary: There has been a growing interest in using microfluidic devices for saliva analysis in recent years. This approach has the potential to provide more sensitive and selective analysis by collecting large quantities of saliva samples. The aim of this review is to provide an update on the use of microfluidic devices for salivary biomarker analysis.
Article
Chemistry, Analytical
Bryan Ang, Ruhollah Habibi, Ciaren Kett, Wai Hoe Chin, Kellie L. Tuck, Adrian Neild, Victor J. Cadarso
Summary: Microfluidic concentration technology can detect low concentrations of bacteria in samples, making it suitable for time-sensitive situations such as clinical settings and food quality control. By using a packed bed of micro-particles activated by surface acoustic waves, bacteria can be efficiently captured and recovered for further analysis.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Food Science & Technology
Xinyu Liao, Yue Zhang, Qiyi Zhang, Jianwei Zhou, Tian Ding, Jinsong Feng
Summary: This review systematically summarizes the advances in microfluidic systems for detecting foodborne pathogens, with a focus on different substrates and enabled functions. It discusses the integration of IoT for real-time food safety inspection and future directions in microfluidic technology for detecting and monitoring foodborne pathogens.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Biochemical Research Methods
Benjamin Krafft, Anna Tycova, Raphael D. Urban, Christian Dusny, Detlev Belder
Summary: This study introduces a disposable and low-cost lab-on-a-chip device utilizing a nanoporous membrane for the identification of bacterial pathogens in drinking water. The device showed promising results in rapid and reliable pathogen detection, making it suitable for common pathogens in spiked tap water.
Article
Biotechnology & Applied Microbiology
Pei-Wei Lee, Marissa Totten, Liben Chen, Fan-En Chen, Alexander Y. Trick, Kushagra Shah, Hoan Thanh Ngo, Mei Jin, Kuangwen Hsieh, Sean X. Zhang, Tza-Huei Wang
Summary: Candida auris is an emerging multidrug-resistant fungal pathogen that has spread widely. Researchers have developed a POC device based on Droplet magnetofluidics technology to quickly detect the presence of C. auris.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biophysics
Wan Wang, Shounian Ding, Zhijuan Wang, Qing Lv, Qing Zhang
Summary: In this study, a microfluidic paper-based analytical device (muPAD) was developed for the online isolation of proteins and electrochemical detection of lead ions (Pb(II)) in urine samples. Experimental parameters were optimized, leading to a maximum protein concentration of 300 mg L-1, a linear range of 10-500 µg L-1, and a detection limit of 9 µg L-1. The device's effectiveness was demonstrated through quantification of Pb(II) in urine samples, showing results consistent with atomic absorption spectrometry (AAS).
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Manpreet Kaur, Dorin Harpaz, Evgeni Eltzov
Summary: A gelatin-based colorimetric assay was developed for the rapid detection of Bacillus cereus in food. The assay is low-cost, simple, and portable, and has a comparable detection range to existing methods.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Albert Alvarez-Carulla, Yaiza Montes-Cebrian, Jordi Colomer-Farrarons, Pere Lluis Miribel-Catala
Summary: A novel self-powered, point-of-care, low-power electronic method for sample concentration measurement using galvanic cell, provides digital user-readable result without external devices, validated with NaCl solution as electrolyte, and exhibits a maximum coefficient of variation of 6.1%.
Article
Chemistry, Analytical
Suhyeon Kim, Hyoryung Nam, Eunji Lee, Ji-Won Huh, You-Me Kim, Hyungkook Jeon, Geunbae Lim
Summary: We have developed a multifunctional microfluidic device that can lyse cells and separate intracellular components, offering advantages of simple fabrication, low cost, and bubble-free operation. The device utilizes an amplified electric field in the ion-depletion region formed by ion concentration polarization, allowing for sequential processing of cell lysis and separation of nano-sized components.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Multidisciplinary
Yanan Ma, Yang Yue, Hang Zhang, Feng Cheng, Wanqiu Zhao, Jiangyu Rao, Shijun Luo, Jie Wang, Xueliang Jiang, Zhitian Liu, Nishuang Liu, Yihua Gao
Article
Chemistry, Multidisciplinary
Jie Wang, Yue Dong, Yiwei Li, Wei Li, Kai Cheng, Yuan Qian, Guoqiang Xu, Xiaoshuai Zhang, Liang Hu, Peng Chen, Wei Du, Xiaojun Feng, Yuan-Di Zhao, Zhihong Zhang, Bi-Feng Liu
ADVANCED FUNCTIONAL MATERIALS
(2018)
Article
Biophysics
Liang Hu, Anle Ge, Xixian Wang, Shanshan Wang, Xinpei Yue, Jie Wang, Xiaojun Feng, Wei Du, Bi-Feng Liu
BIOSENSORS & BIOELECTRONICS
(2018)
Article
Chemistry, Analytical
Jie Wang, Wei Li, Lin Ban, Wei Du, Xiaojun Feng, Bi-Feng Liu
SENSORS AND ACTUATORS B-CHEMICAL
(2018)
Article
Chemistry, Analytical
Peng Chen, Shuangqian Yan, Jie Wang, Yiran Guo, Yue Dong, Xiaojun Feng, Xuemei Zeng, Yiwei Li, Wei Du, Bi-Feng Liu
ANALYTICAL CHEMISTRY
(2019)
Article
Chemistry, Analytical
Yachao Wang, Jinchi Zhu, Peng Chen, Yiwei Li, Shuangqian Yan, Jie Wang, Wei Du, Bi-Feng Liu
SENSORS AND ACTUATORS B-CHEMICAL
(2019)
Article
Biochemical Research Methods
Yike Wu, Qiuyue Sha, Chang Wang, Bi-Feng Liu, Song Wang, Xin Liu
JOURNAL OF CHROMATOGRAPHY A
(2019)
Article
Multidisciplinary Sciences
Yue Dong, Jie Wang, Xukui Guo, Shanshan Yang, Mehmet Ozgun Ozen, Peng Chen, Xin Liu, Wei Du, Fei Xiao, Utkan Demirci, Bi-Feng Liu
NATURE COMMUNICATIONS
(2019)
Review
Chemistry, Multidisciplinary
Fernando Soto, Jie Wang, Rajib Ahmed, Utkan Demirci
Review
Chemistry, Multidisciplinary
Jie Wang, Peng Ma, Daniel H. Kim, Bi-Feng Liu, Utkan Demirci
Summary: Exosomes, nano-sized extracellular vesicles secreted by cells, have revolutionized various areas such as liquid biopsies, cancer biology, drug delivery, and immunotherapy. Microfluidic platforms show promise in overcoming the limitations of conventional techniques by offering high precision processing, microscale liquid handling, and integration with various functional units for efficient exosome separation and sensing.
Article
Chemistry, Analytical
Chungen Qian, Yujin Xiao, Jie Wang, Yiwei Li, Shunji Li, Bo Wei, Wei Du, Xiaojun Feng, Peng Chen, Bi-Feng Liu
Summary: Exosomes, along with their associated proteins and nucleic acids, are recognized as biomarkers for tumor diagnosis and prognosis. Detecting exosomes is challenging due to their small size and low concentration. A low-cost, rapid, and portable agarose-based microfluidic chip for exosome concentration and in situ exosomal microRNA detection was developed, providing a new avenue for early cancer detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Review
Automation & Control Systems
Fernando Soto, Jie Wang, Shreya Deshmukh, Utkan Demirci
Summary: The article introduces the latest developments in externally driven assembly of synthetic and biological components, emphasizing the importance of reversibility in creating multiscale systems. By controlling magnetic, acoustic, optical, and electric fields, the assembly of biological and synthetic subunits can be reprogrammed. The article also highlights the ability to dynamically actuate assembly configurations by modulating the properties of external stimuli, and presents design principles for reconfigurable structures.
ADVANCED INTELLIGENT SYSTEMS
(2021)
Article
Chemistry, Multidisciplinary
Yue Dong, Lu Wang, Jie Wang, Shijie Wang, Yu Wang, Dongdong Jin, Peng Chen, Wei Du, Li Zhang, Bi-Feng Liu
Article
Chemistry, Multidisciplinary
Jie Wang, Rajib Ahmed, Yitian Zeng, Kaiyu Fu, Fernando Soto, Bob Sinclair, Hyongsok Tom Soh, Utkan Demirci
Article
Chemistry, Multidisciplinary
Yue Dong, Chen Yi, Shanshan Yang, Jie Wang, Peng Chen, Xin Liu, Wei Du, Song Wang, Bi-Feng Liu